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Search
101.
Kang, Sin-Hwa; Phan, Thai; Bolas, Mark; Krum, David M.
User Perceptions of a Virtual Human Over Mobile Video Chat Interactions Book Section
In: Human-Computer Interaction. Novel User Experiences, vol. 9733, pp. 107–118, Springer International Publishing, Cham, Switzerland, 2016, ISBN: 978-3-319-39512-8 978-3-319-39513-5.
@incollection{kang_user_2016,
title = {User Perceptions of a Virtual Human Over Mobile Video Chat Interactions},
author = {Sin-Hwa Kang and Thai Phan and Mark Bolas and David M. Krum},
url = {http://download.springer.com/static/pdf/913/chp%253A10.1007%252F978-3-319-39513-5_10.pdf?originUrl=http%3A%2F%2Flink.springer.com%2Fchapter%2F10.1007%2F978-3-319-39513-5_10&token2=exp=1474906977 acl=%2Fstatic%2Fpdf%2F913%2Fchp%25253A10.1007%25252F978-3-319-39513-5_10.pdf%3ForiginUrl%3Dhttp%253A%252F%252Flink.springer.com%252Fchapter%252F10.1007%252F978-3-319-39513-5_10* hmac=14d38ee320936bf1edfc65a0d3fcc0855c42e0baba46e0f3a9a81293698b8b68},
isbn = {978-3-319-39512-8 978-3-319-39513-5},
year = {2016},
date = {2016-06-01},
booktitle = {Human-Computer Interaction. Novel User Experiences},
volume = {9733},
pages = {107–118},
publisher = {Springer International Publishing},
address = {Cham, Switzerland},
abstract = {We believe that virtual humans, presented over video chat services, such as Skype, and delivered using smartphones, can be an effective way to deliver innovative applications where social interactions are important, such as counseling and coaching. To explore this subject, we have built a hardware and software apparatus that allows virtual humans to initiate, receive, and interact over video calls using Skype or any similar service. With this platform, we conducted two experiments to investigate the applications and characteristics of virtual humans that interact over mobile video. In Experiment 1, we investigated user reactions to the physical realism of the background scene in which a virtual human was displayed. In Experiment 2, we examined how virtual characters can establish and maintain longer term relationships with users, using ideas from Social Exchange Theory to strengthen bonds between interactants. Experiment 2 involved repeated interactions with a virtual human over a period of time. Both studies used counseling-style interactions with users. The results demonstrated that males were more attracted socially to a virtual human that was presented over a realistic background than a featureless background while females were more socially attracted to a virtual human with a less realistic featureless background. The results further revealed that users felt the virtual human was a compassionate partner when they interacted with the virtual human over multiple calls, rather than just a single call.},
keywords = {},
pubstate = {published},
tppubtype = {incollection}
}
We believe that virtual humans, presented over video chat services, such as Skype, and delivered using smartphones, can be an effective way to deliver innovative applications where social interactions are important, such as counseling and coaching. To explore this subject, we have built a hardware and software apparatus that allows virtual humans to initiate, receive, and interact over video calls using Skype or any similar service. With this platform, we conducted two experiments to investigate the applications and characteristics of virtual humans that interact over mobile video. In Experiment 1, we investigated user reactions to the physical realism of the background scene in which a virtual human was displayed. In Experiment 2, we examined how virtual characters can establish and maintain longer term relationships with users, using ideas from Social Exchange Theory to strengthen bonds between interactants. Experiment 2 involved repeated interactions with a virtual human over a period of time. Both studies used counseling-style interactions with users. The results demonstrated that males were more attracted socially to a virtual human that was presented over a realistic background than a featureless background while females were more socially attracted to a virtual human with a less realistic featureless background. The results further revealed that users felt the virtual human was a compassionate partner when they interacted with the virtual human over multiple calls, rather than just a single call.
102.
Nolin, Pierre; Stipanicic, Annie; Henry, Mylène; Lachapelle, Yves; Lussier-Desrochers, Dany; Rizzo, Albert “Skip”; Allain, Philippe
ClinicaVR: Classroom-CPT: A virtual reality tool for assessing attention and inhibition in children and adolescents Journal Article
In: Computers in Human Behavior, vol. 59, pp. 327–333, 2016, ISSN: 07475632.
@article{nolin_clinicavr_2016,
title = {ClinicaVR: Classroom-CPT: A virtual reality tool for assessing attention and inhibition in children and adolescents},
author = {Pierre Nolin and Annie Stipanicic and Mylène Henry and Yves Lachapelle and Dany Lussier-Desrochers and Albert “Skip” Rizzo and Philippe Allain},
url = {http://linkinghub.elsevier.com/retrieve/pii/S0747563216300759},
doi = {10.1016/j.chb.2016.02.023},
issn = {07475632},
year = {2016},
date = {2016-06-01},
journal = {Computers in Human Behavior},
volume = {59},
pages = {327–333},
abstract = {Having garnered interest both in clinic and research areas, the Virtual Classroom (Rizzo et al., 2000) assesses children's attention in a virtual context. The Digital MediaWorks team (www.dmw.ca) has evolved the original basic classroom concept over a number of iterations to form the ClinicaVR Suite containing the Classroom-CPT as one of its components. The present study has three aims: investigate certain validity and reliability aspects of the tool; examine the relationship between performance in the virtual test and the attendant sense of presence and cybersickness experienced by participants; assess potential effects of gender and age on performance in the test. The study was conducted with 102 children and adolescents from Grade 2 to Grade 10. All participants were enrolled in a regular school program. Results support both concurrent and construct validity as well as temporal stability of ClinicaVR: Classroom-Continuous Performance Test (CPT). Gender exerted no effect on performance, while age did. The test did not cause much cybersickness. We recommend ClinicaVR: Classroom-CPT as an assessment tool for selective and sustained attention, and inhibition, in clinic and research domains.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Having garnered interest both in clinic and research areas, the Virtual Classroom (Rizzo et al., 2000) assesses children's attention in a virtual context. The Digital MediaWorks team (www.dmw.ca) has evolved the original basic classroom concept over a number of iterations to form the ClinicaVR Suite containing the Classroom-CPT as one of its components. The present study has three aims: investigate certain validity and reliability aspects of the tool; examine the relationship between performance in the virtual test and the attendant sense of presence and cybersickness experienced by participants; assess potential effects of gender and age on performance in the test. The study was conducted with 102 children and adolescents from Grade 2 to Grade 10. All participants were enrolled in a regular school program. Results support both concurrent and construct validity as well as temporal stability of ClinicaVR: Classroom-Continuous Performance Test (CPT). Gender exerted no effect on performance, while age did. The test did not cause much cybersickness. We recommend ClinicaVR: Classroom-CPT as an assessment tool for selective and sustained attention, and inhibition, in clinic and research domains.
103.
Mühlberger, Andreas; Jekel, K.; Probst, Thomas; Schecklmann, Martin; Conzelmann, A.; Andreatta, M.; Rizzo, A. A.; Pauli, P.; Romanos, M.
The Influence of Methylphenidate on Hyperactivity and Attention Deficits in Children With ADHD: A Virtual Classroom Test Journal Article
In: Journal of attention disorders, 2016.
@article{muhlberger_influence_2016,
title = {The Influence of Methylphenidate on Hyperactivity and Attention Deficits in Children With ADHD: A Virtual Classroom Test},
author = {Andreas Mühlberger and K. Jekel and Thomas Probst and Martin Schecklmann and A. Conzelmann and M. Andreatta and A. A. Rizzo and P. Pauli and M. Romanos},
url = {http://journals.sagepub.com/doi/abs/10.1177/1087054716647480},
doi = {10.1177/1087054716647480},
year = {2016},
date = {2016-05-01},
journal = {Journal of attention disorders},
abstract = {This study compares the performance in a continuous performance test within a virtual reality classroom (CPT-VRC) between medicated children with ADHD, unmedicated children with ADHD, and healthy children. Method:N = 94 children with ADHD (n = 26 of them received methylphenidate and n = 68 were unmedicated) and n = 34 healthy children performed the CPT-VRC. Omission errors, reaction time/variability, commission errors, and body movements were assessed. Furthermore, ADHD questionnaires were administered and compared with the CPT-VRC measures. Results: The unmedicated ADHD group exhibited more omission errors and showed slower reaction times than the healthy group. Reaction time variability was higher in the unmedicated ADHD group compared with both the healthy and the medicated ADHD group. Omission errors and reaction time variability were associated with inattentiveness ratings of experimenters. Head movements were correlated with hyperactivity ratings of parents and experimenters. Conclusion: Virtual reality is a promising technology to assess ADHD symptoms in an ecologically valid environment.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
This study compares the performance in a continuous performance test within a virtual reality classroom (CPT-VRC) between medicated children with ADHD, unmedicated children with ADHD, and healthy children. Method:N = 94 children with ADHD (n = 26 of them received methylphenidate and n = 68 were unmedicated) and n = 34 healthy children performed the CPT-VRC. Omission errors, reaction time/variability, commission errors, and body movements were assessed. Furthermore, ADHD questionnaires were administered and compared with the CPT-VRC measures. Results: The unmedicated ADHD group exhibited more omission errors and showed slower reaction times than the healthy group. Reaction time variability was higher in the unmedicated ADHD group compared with both the healthy and the medicated ADHD group. Omission errors and reaction time variability were associated with inattentiveness ratings of experimenters. Head movements were correlated with hyperactivity ratings of parents and experimenters. Conclusion: Virtual reality is a promising technology to assess ADHD symptoms in an ecologically valid environment.
104.
TALBOT, Thomas B.; KALISCH, Nicolai; CHRISTOFFERSEN, Kelly; LUCAS, Gale; FORBELL, Eric
Natural Language Understanding Performance & Use Considerations in Virtual Medical Encounters. Journal Article
In: Medicine Meets Virtual Reality 22: NextMed/MMVR22, vol. 220, pp. 407–413, 2016.
@article{talbot_natural_2016,
title = {Natural Language Understanding Performance & Use Considerations in Virtual Medical Encounters.},
author = {Thomas B. TALBOT and Nicolai KALISCH and Kelly CHRISTOFFERSEN and Gale LUCAS and Eric FORBELL},
url = {http://books.google.com/books?hl=en&lr=&id=sLgtDAAAQBAJ&oi=fnd&pg=PA407&dq=%22through+regular+web+browsers+and+is+capable+of+multiple+types+of%22+%22practice+targeting+diagnostic+interviews.+A+natural+language+interview%22+%22narrative+statement+based+upon+dialog+context.+The+dialog+manager%27s%22+&ots=Ej8L8hxLlb&sig=GMnqEb5n7CB9x1lWE4gfe5_4n8o},
doi = {10.3233/978-1-61499-625-5-407},
year = {2016},
date = {2016-04-01},
journal = {Medicine Meets Virtual Reality 22: NextMed/MMVR22},
volume = {220},
pages = {407–413},
abstract = {A virtual standardized patient (VSP) prototype was tested for natural language understanding (NLU) performance. The conversational VSP was evaluated in a controlled 61 subject study over four repetitions of a patient case. The prototype achieved more than 92% appropriate response rate from naïve users on their first attempt and results were stable by their fourth case repetition. This level of performance exceeds prior efforts and is at a level comparable of accuracy as seen in human conversational patient training, with caveats. This level of performance was possible due to the use of a unified medical taxonomy underpinning that allows virtual patient language training to be applied to all cases in our system as opposed to benefiting a single patient case.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
A virtual standardized patient (VSP) prototype was tested for natural language understanding (NLU) performance. The conversational VSP was evaluated in a controlled 61 subject study over four repetitions of a patient case. The prototype achieved more than 92% appropriate response rate from naïve users on their first attempt and results were stable by their fourth case repetition. This level of performance exceeds prior efforts and is at a level comparable of accuracy as seen in human conversational patient training, with caveats. This level of performance was possible due to the use of a unified medical taxonomy underpinning that allows virtual patient language training to be applied to all cases in our system as opposed to benefiting a single patient case.
105.
RIZZO, Albert; LUCAS, Gale; GRATCH, Jonathan; STRATOU, Giota; MORENCY, Louis-Philippe; CHAVEZ, Kenneth; SHILLING, Russ; SCHERER, Stefan
Automatic Behavior Analysis During a Clinical Interview with a Virtual Human. Journal Article
In: Medicine Meets Virtual Reality 22: NextMed/MMVR22, vol. 220, pp. 316–322, 2016.
@article{rizzo_automatic_2016,
title = {Automatic Behavior Analysis During a Clinical Interview with a Virtual Human.},
author = {Albert RIZZO and Gale LUCAS and Jonathan GRATCH and Giota STRATOU and Louis-Philippe MORENCY and Kenneth CHAVEZ and Russ SHILLING and Stefan SCHERER},
url = {http://books.google.com/books?hl=en&lr=&id=sLgtDAAAQBAJ&oi=fnd&pg=PA316&dq=%22captured+across+a+20+minute+interview.+Results+from+of+sample+of+service%22+%22technology+for+clinical+purposes.+Recent+shifts+in+the+social+and%22+%22needed+to+create+VH+systems+is+now+driving+application+development+across%22+&ots=Ej8M4iuPfb&sig=Ad6Z3DPSwN3qA2gMDKWPe1YTPhg},
year = {2016},
date = {2016-04-01},
journal = {Medicine Meets Virtual Reality 22: NextMed/MMVR22},
volume = {220},
pages = {316–322},
abstract = {SimSensei is a Virtual Human (VH) interviewing platform that uses off-the-shelf sensors (i.e., webcams, Microsoft Kinect and a microphone) to capture and interpret real-time audiovisual behavioral signals from users interacting with the VH system. The system was specifically designed for clinical interviewing and health care support by providing a face-to-face interaction between a user and a VH that can automatically react to the inferred state of the user through analysis of behavioral signals gleaned from the user’s facial expressions, body gestures and vocal parameters. Akin to how non-verbal behavioral signals have an impact on human-to-human interaction and communication, SimSensei aims to capture and infer user state from signals generated from user non-verbal communication to improve engagement between a VH and a user and to quantify user state from the data captured across a 20 minute interview. Results from of sample of service members (SMs) who were interviewed before and after a deployment to Afghanistan indicate that SMs reveal more PTSD symptoms to the VH than they report on the Post Deployment Health Assessment. Pre/Post deployment facial expression analysis indicated more sad expressions and few happy expressions at post deployment.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
SimSensei is a Virtual Human (VH) interviewing platform that uses off-the-shelf sensors (i.e., webcams, Microsoft Kinect and a microphone) to capture and interpret real-time audiovisual behavioral signals from users interacting with the VH system. The system was specifically designed for clinical interviewing and health care support by providing a face-to-face interaction between a user and a VH that can automatically react to the inferred state of the user through analysis of behavioral signals gleaned from the user’s facial expressions, body gestures and vocal parameters. Akin to how non-verbal behavioral signals have an impact on human-to-human interaction and communication, SimSensei aims to capture and infer user state from signals generated from user non-verbal communication to improve engagement between a VH and a user and to quantify user state from the data captured across a 20 minute interview. Results from of sample of service members (SMs) who were interviewed before and after a deployment to Afghanistan indicate that SMs reveal more PTSD symptoms to the VH than they report on the Post Deployment Health Assessment. Pre/Post deployment facial expression analysis indicated more sad expressions and few happy expressions at post deployment.
106.
Krum, David M.; Kang, Sin-Hwa; Phan, Thai; Dukes, Lauren Cairco; Bolas, Mark
Head Mounted Projection for Enhanced Gaze in Social Interactions Proceedings Article
In: 2016 IEEE Virtual Reality (VR), pp. 209–210, IEEE, Greenville, SC, 2016.
@inproceedings{krum_head_2016,
title = {Head Mounted Projection for Enhanced Gaze in Social Interactions},
author = {David M. Krum and Sin-Hwa Kang and Thai Phan and Lauren Cairco Dukes and Mark Bolas},
url = {http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7504727},
doi = {10.1109/VR.2016.7504727},
year = {2016},
date = {2016-03-01},
booktitle = {2016 IEEE Virtual Reality (VR)},
pages = {209–210},
publisher = {IEEE},
address = {Greenville, SC},
abstract = {Projected displays can present life-sized imagery of a virtual human character that can be seen by multiple observers. However, typical projected displays can only render that virtual human from a single viewpoint, regardless of whether head tracking is employed. This results in the virtual human being rendered from an incorrect perspective for most individuals. This could cause perceptual miscues, such as the “Mona Lisa” effect, causing the virtual human to appear as if it is simultaneously gazing and pointing at all observers regardless of their location. This may be detrimental to training scenarios in which all trainees must accurately assess where the virtual human is looking or pointing a weapon. We discuss our investigations into the presentation of eye gaze using REFLCT, a previously introduced head mounted projective display. REFLCT uses head tracked, head mounted projectors and retroreflective screens to present personalized, perspective correct imagery to multiple users without the occlusion of a traditional head mounted display. We examined how head mounted projection for enhanced presentation of eye gaze might facilitate or otherwise affect social interactions during a multi-person guessing game of “Twenty Questions.”},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
Projected displays can present life-sized imagery of a virtual human character that can be seen by multiple observers. However, typical projected displays can only render that virtual human from a single viewpoint, regardless of whether head tracking is employed. This results in the virtual human being rendered from an incorrect perspective for most individuals. This could cause perceptual miscues, such as the “Mona Lisa” effect, causing the virtual human to appear as if it is simultaneously gazing and pointing at all observers regardless of their location. This may be detrimental to training scenarios in which all trainees must accurately assess where the virtual human is looking or pointing a weapon. We discuss our investigations into the presentation of eye gaze using REFLCT, a previously introduced head mounted projective display. REFLCT uses head tracked, head mounted projectors and retroreflective screens to present personalized, perspective correct imagery to multiple users without the occlusion of a traditional head mounted display. We examined how head mounted projection for enhanced presentation of eye gaze might facilitate or otherwise affect social interactions during a multi-person guessing game of “Twenty Questions.”
107.
Cukor, Judith; Gerardi, Maryrose; Alley, Stephanie; Reist, Christopher; Roy, Michael; Rothbaum, Barbara O.; Difede, JoAnn; Rizzo, Albert
Virtual Reality Exposure Therapy for Combat-Related PTSD Book Section
In: Posttraumatic Stress Disorder and Related Diseases in Combat Veterans, pp. 69–83, Springer International Publishing, Cham, Switzerland, 2016, ISBN: 978-3-319-22984-3 978-3-319-22985-0.
@incollection{cukor_virtual_2016,
title = {Virtual Reality Exposure Therapy for Combat-Related PTSD},
author = {Judith Cukor and Maryrose Gerardi and Stephanie Alley and Christopher Reist and Michael Roy and Barbara O. Rothbaum and JoAnn Difede and Albert Rizzo},
url = {http://link.springer.com/10.1007/978-3-319-22985-0_7},
isbn = {978-3-319-22984-3 978-3-319-22985-0},
year = {2016},
date = {2016-01-01},
booktitle = {Posttraumatic Stress Disorder and Related Diseases in Combat Veterans},
pages = {69–83},
publisher = {Springer International Publishing},
address = {Cham, Switzerland},
abstract = {War is perhaps one of the most challenging situations that a human being can experience. The physical, emotional, cognitive, and psychological demands of a combat environment place enormous stress on even the best-prepared military personnel. Numerous reports indicate that the incidence of posttraumatic stress disorder (PTSD) in returning Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) military personnel is significant. This has served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD that leverage the unique features available with virtual reality (VR) technology. VR-delivered exposure therapy for PTSD is currently being used to treat combatand terrorist attack-related PTSD with initial reports of positive outcomes. This chapter presents a brief overview and rationale for the use of VR exposure for combat-related PTSD and describes the Virtual Iraq/Afghanistan exposure therapy system. This includes a short review of the previous literature, a description of the system components and the treatment protocol, and a case presentation. VR offers an alternative format for delivering exposure-based therapies for PTSD that may appeal to certain service members and veterans who grew up “digital” and who might be inclined to seek treatment in this fashion.},
keywords = {},
pubstate = {published},
tppubtype = {incollection}
}
War is perhaps one of the most challenging situations that a human being can experience. The physical, emotional, cognitive, and psychological demands of a combat environment place enormous stress on even the best-prepared military personnel. Numerous reports indicate that the incidence of posttraumatic stress disorder (PTSD) in returning Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) military personnel is significant. This has served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD that leverage the unique features available with virtual reality (VR) technology. VR-delivered exposure therapy for PTSD is currently being used to treat combatand terrorist attack-related PTSD with initial reports of positive outcomes. This chapter presents a brief overview and rationale for the use of VR exposure for combat-related PTSD and describes the Virtual Iraq/Afghanistan exposure therapy system. This includes a short review of the previous literature, a description of the system components and the treatment protocol, and a case presentation. VR offers an alternative format for delivering exposure-based therapies for PTSD that may appeal to certain service members and veterans who grew up “digital” and who might be inclined to seek treatment in this fashion.
108.
Scherer, Stefan; Lucas, Gale M.; Gratch, Jonathan; Rizzo, Albert Skip; Morency, Louis-Philippe
Self-reported symptoms of depression and PTSD are associated with reduced vowel space in screening interviews Journal Article
In: IEEE Transactions on Affective Computing, vol. 7, no. 1, pp. 59–73, 2016, ISSN: 1949-3045.
@article{scherer_self-reported_2016,
title = {Self-reported symptoms of depression and PTSD are associated with reduced vowel space in screening interviews},
author = {Stefan Scherer and Gale M. Lucas and Jonathan Gratch and Albert Skip Rizzo and Louis-Philippe Morency},
url = {http://ieeexplore.ieee.org/document/7117386/?arnumber=7117386},
doi = {10.1109/TAFFC.2015.2440264},
issn = {1949-3045},
year = {2016},
date = {2016-01-01},
journal = {IEEE Transactions on Affective Computing},
volume = {7},
number = {1},
pages = {59–73},
abstract = {Reduced frequency range in vowel production is a well documented speech characteristic of individuals’ with psychological and neurological disorders. Affective disorders such as depression and post-traumatic stress disorder (PTSD) are known to influence motor control and in particular speech production. The assessment and documentation of reduced vowel space and reduced expressivity often either rely on subjective assessments or on analysis of speech under constrained laboratory conditions (e.g.sustained vowel production, reading tasks). These constraints render the analysis of such measures expensive and impractical. Within this work, we investigate an automatic unsupervised machine learning based approach to assess a speaker’s vowel space. Our experiments are based on recordings of 253 individuals. Symptoms of depression and PTSD are assessed using standard self-assessment questionnaires and their cut-off scores. The experiments show a significantly reduced vowel space in subjects that scored positively on the questionnaires. We show the measure’s statistical robustness against varying demographics of individuals and articulation rate. The reduced vowel space for subjects with symptoms of depression can be explained by the common condition of psychomotor retardation influencing articulation and motor control. These findings could potentially support treatment of affective disorders, like depression and PTSD in the future.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Reduced frequency range in vowel production is a well documented speech characteristic of individuals’ with psychological and neurological disorders. Affective disorders such as depression and post-traumatic stress disorder (PTSD) are known to influence motor control and in particular speech production. The assessment and documentation of reduced vowel space and reduced expressivity often either rely on subjective assessments or on analysis of speech under constrained laboratory conditions (e.g.sustained vowel production, reading tasks). These constraints render the analysis of such measures expensive and impractical. Within this work, we investigate an automatic unsupervised machine learning based approach to assess a speaker’s vowel space. Our experiments are based on recordings of 253 individuals. Symptoms of depression and PTSD are assessed using standard self-assessment questionnaires and their cut-off scores. The experiments show a significantly reduced vowel space in subjects that scored positively on the questionnaires. We show the measure’s statistical robustness against varying demographics of individuals and articulation rate. The reduced vowel space for subjects with symptoms of depression can be explained by the common condition of psychomotor retardation influencing articulation and motor control. These findings could potentially support treatment of affective disorders, like depression and PTSD in the future.
109.
Venek, Verena; Scherer, Stefan; Morency, Louis-Philippe; Rizzo, Albert; Pestian, John
Adolescent Suicidal Risk Assessment in Clinician-Patient Interaction Journal Article
In: IEEE Transactions on Affective Computing, vol. PP, no. 99, 2016, ISSN: 1949-3045.
@article{venek_adolescent_2016,
title = {Adolescent Suicidal Risk Assessment in Clinician-Patient Interaction},
author = {Verena Venek and Stefan Scherer and Louis-Philippe Morency and Albert Rizzo and John Pestian},
url = {http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7384418},
doi = {10.1109/TAFFC.2016.2518665},
issn = {1949-3045},
year = {2016},
date = {2016-01-01},
journal = {IEEE Transactions on Affective Computing},
volume = {PP},
number = {99},
abstract = {Youth suicide is a major public health problem. It is the third leading cause of death in the United States for ages 13 through 18. Many adolescents that face suicidal thoughts or make a suicide plan never seek professional care or help. Within this work, we evaluate both verbal and nonverbal responses to a five-item ubiquitous questionnaire to identify and assess suicidal risk of adolescents. We utilize a machine learning approach to identify suicidal from non-suicidal speech as well as characterize adolescents that repeatedly attempted suicide in the past. Our findings investigate both verbal and nonverbal behavior information of the face-to-face clinician-patient interaction. We investigate 60 audio-recorded dyadic clinician-patient interviews of 30 suicidal (13 repeaters and 17 non-repeaters) and 30 non-suicidal adolescents. The interaction between clinician and adolescents is statistically analyzed to reveal differences between suicidal vs. non-suicidal adolescents and to investigate suicidal repeaters’ behaviors in comparison to suicidal non-repeaters. By using a hierarchical classifier we were able to show that the verbal responses to the ubiquitous questions sections of the interviews were useful to discriminate suicidal and non-suicidal patients. However, to additionally classify suicidal repeaters and suicidal non-repeaters more information especially nonverbal information is required.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Youth suicide is a major public health problem. It is the third leading cause of death in the United States for ages 13 through 18. Many adolescents that face suicidal thoughts or make a suicide plan never seek professional care or help. Within this work, we evaluate both verbal and nonverbal responses to a five-item ubiquitous questionnaire to identify and assess suicidal risk of adolescents. We utilize a machine learning approach to identify suicidal from non-suicidal speech as well as characterize adolescents that repeatedly attempted suicide in the past. Our findings investigate both verbal and nonverbal behavior information of the face-to-face clinician-patient interaction. We investigate 60 audio-recorded dyadic clinician-patient interviews of 30 suicidal (13 repeaters and 17 non-repeaters) and 30 non-suicidal adolescents. The interaction between clinician and adolescents is statistically analyzed to reveal differences between suicidal vs. non-suicidal adolescents and to investigate suicidal repeaters’ behaviors in comparison to suicidal non-repeaters. By using a hierarchical classifier we were able to show that the verbal responses to the ubiquitous questions sections of the interviews were useful to discriminate suicidal and non-suicidal patients. However, to additionally classify suicidal repeaters and suicidal non-repeaters more information especially nonverbal information is required.
110.
Rizzo, Albert; Talbot, Thomas
Virtual Reality Standardized Patients for Clinical Training Book Section
In: The Digital Patient, pp. 255–272, John Wiley & Sons, Inc, Hoboken, NJ, 2016, ISBN: 978-1-118-95278-8 978-1-118-95275-7.
@incollection{rizzo_virtual_2016,
title = {Virtual Reality Standardized Patients for Clinical Training},
author = {Albert Rizzo and Thomas Talbot},
url = {http://doi.wiley.com/10.1002/9781118952788.ch18},
isbn = {978-1-118-95278-8 978-1-118-95275-7},
year = {2016},
date = {2016-01-01},
booktitle = {The Digital Patient},
pages = {255–272},
publisher = {John Wiley & Sons, Inc},
address = {Hoboken, NJ},
abstract = {There are several quite distinct educational approaches that are all called a virtual patient. It includes case presentations, interactive patient scenarios, virtual patient games, human standardized patients (HSPs), high-fidelity software simulations, high-fidelity manikins, and virtual human (VH) conversational agents. VH conversations are possible that include an avatar that responds to pre-selected choices; such an interview is called a structured encounter. Most VSPs attempted to date have been on traditional computers. With the increased prevalence of mobile devices, it is logical to consider the migration of VSP technology to phones and tablets. Future distant recognition (DSR) systems will require a high level of individual speaker discrimination and will likely adopt microphone array-based acoustic beam forming technology. Future success may no longer be rate-limited by the pace of technology, but by the creativity and innovation of educators who will create compelling VSP experiences and curricula.},
keywords = {},
pubstate = {published},
tppubtype = {incollection}
}
There are several quite distinct educational approaches that are all called a virtual patient. It includes case presentations, interactive patient scenarios, virtual patient games, human standardized patients (HSPs), high-fidelity software simulations, high-fidelity manikins, and virtual human (VH) conversational agents. VH conversations are possible that include an avatar that responds to pre-selected choices; such an interview is called a structured encounter. Most VSPs attempted to date have been on traditional computers. With the increased prevalence of mobile devices, it is logical to consider the migration of VSP technology to phones and tablets. Future distant recognition (DSR) systems will require a high level of individual speaker discrimination and will likely adopt microphone array-based acoustic beam forming technology. Future success may no longer be rate-limited by the pace of technology, but by the creativity and innovation of educators who will create compelling VSP experiences and curricula.
111.
Pynadath, David V.; Wang, Ning; Merchant, Chirag
Toward Acquiring a Human Behavior Model of Competition vs. Cooperation Proceedings Article
In: Interservice/Industry Training, Simulation, and Education Conference (I/ITSEC) 2015, National Training and Simulation Association, Orlando, Florida, 2015.
@inproceedings{pynadath_toward_2015,
title = {Toward Acquiring a Human Behavior Model of Competition vs. Cooperation},
author = {David V. Pynadath and Ning Wang and Chirag Merchant},
url = {http://www.iitsecdocs.com/search},
year = {2015},
date = {2015-12-01},
booktitle = {Interservice/Industry Training, Simulation, and Education Conference (I/ITSEC) 2015},
publisher = {National Training and Simulation Association},
address = {Orlando, Florida},
abstract = {One of the challenges in modeling human behavior is accurately capturing the conditions under which people will behave selfishly or selflessly. Researchers have been unable to craft purely cooperative (or competitive) scenarios without significant numbers of subjects displaying unintended selfish (or selfless) behavior (e.g., Rapoport & Chammah, 1965). In this work, rather than try to further isolate competitive vs. cooperative behavior, we instead construct an experimental setting that deliberately includes both, in a way that fits within an operational simulation model. Using PsychSim, a multiagent social simulation framework with both Theory of Mind and decision theory, we have implemented an online resource allocation game called “Team of Rivals”, where four players seek to defeat a common enemy. The players have individual pools of resources which they can allocate toward that common goal. In addition to their progress toward this common goal, the players also receive individual feedback, in terms of the number of resources they own and have won from the enemy. By giving the players both an explicit cooperative goal and implicit feedback on potential competitive goals, we give them room to behave anywhere on the spectrum between these two extremes. Furthermore, by moving away from the more common two-player laboratory settings (e.g., Prisoner’s Dilemma), we can observe differential behavior across the richer space of possible interpersonal relationships. We discuss the design of the game that allows us to observe and analyze these relationships from human behavior data acquired through this game. We then describe decision-theoretic agents that can simulate hypothesized variations on human behavior. Finally, we present results of a preliminary playtest of the testbed and discuss the gathered data.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
One of the challenges in modeling human behavior is accurately capturing the conditions under which people will behave selfishly or selflessly. Researchers have been unable to craft purely cooperative (or competitive) scenarios without significant numbers of subjects displaying unintended selfish (or selfless) behavior (e.g., Rapoport & Chammah, 1965). In this work, rather than try to further isolate competitive vs. cooperative behavior, we instead construct an experimental setting that deliberately includes both, in a way that fits within an operational simulation model. Using PsychSim, a multiagent social simulation framework with both Theory of Mind and decision theory, we have implemented an online resource allocation game called “Team of Rivals”, where four players seek to defeat a common enemy. The players have individual pools of resources which they can allocate toward that common goal. In addition to their progress toward this common goal, the players also receive individual feedback, in terms of the number of resources they own and have won from the enemy. By giving the players both an explicit cooperative goal and implicit feedback on potential competitive goals, we give them room to behave anywhere on the spectrum between these two extremes. Furthermore, by moving away from the more common two-player laboratory settings (e.g., Prisoner’s Dilemma), we can observe differential behavior across the richer space of possible interpersonal relationships. We discuss the design of the game that allows us to observe and analyze these relationships from human behavior data acquired through this game. We then describe decision-theoretic agents that can simulate hypothesized variations on human behavior. Finally, we present results of a preliminary playtest of the testbed and discuss the gathered data.
112.
Kang, Sin-Hwa; Krum, David M.; Phan, Thai; Bolas, Mark
"Hi, It's Me Again!": Virtual Coaches over Mobile Video Proceedings Article
In: Proceedings of the 3rd International Conference on Human-Agent Interaction, pp. 183–186, ACM, Daegu, Korea, 2015, ISBN: 978-1-4503-3527-0.
@inproceedings{kang_hi_2015,
title = {"Hi, It's Me Again!": Virtual Coaches over Mobile Video},
author = {Sin-Hwa Kang and David M. Krum and Thai Phan and Mark Bolas},
url = {http://dl.acm.org/citation.cfm?id=2814970},
isbn = {978-1-4503-3527-0},
year = {2015},
date = {2015-10-01},
booktitle = {Proceedings of the 3rd International Conference on Human-Agent Interaction},
pages = {183–186},
publisher = {ACM},
address = {Daegu, Korea},
abstract = {We believe that virtual humans presented over video chat services, such as Skype via smartphones, can be an effective way to deliver innovative applications where social interactions are important, such as counseling and coaching. We hypothesize that the context of a smartphone communication channel, i.e. how a virtual human is presented within a smartphone app, and indeed, the nature of that app, can profoundly affect how a real human perceives the virtual human. We have built an apparatus that allows virtual humans to initiate, receive, and interact over video calls using Skype or any similar service. With this platform, we are examining effective designs and social implications of virtual humans that interact over mobile video. The current study examines a relationship involving repeated counseling-style interactions with a virtual human, leveraging the virtual human’s ability to call and interact with a real human on multiple occasions over a period of time. The results and implications of this preliminary study suggest that repeated interactions may improve perceived social characteristics of the virtual human.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
We believe that virtual humans presented over video chat services, such as Skype via smartphones, can be an effective way to deliver innovative applications where social interactions are important, such as counseling and coaching. We hypothesize that the context of a smartphone communication channel, i.e. how a virtual human is presented within a smartphone app, and indeed, the nature of that app, can profoundly affect how a real human perceives the virtual human. We have built an apparatus that allows virtual humans to initiate, receive, and interact over video calls using Skype or any similar service. With this platform, we are examining effective designs and social implications of virtual humans that interact over mobile video. The current study examines a relationship involving repeated counseling-style interactions with a virtual human, leveraging the virtual human’s ability to call and interact with a real human on multiple occasions over a period of time. The results and implications of this preliminary study suggest that repeated interactions may improve perceived social characteristics of the virtual human.
113.
Kang, Sin-Hwa; Feng, Andrew W.; Leuski, Anton; Casas, Dan; Shapiro, Ari
The Effect of An Animated Virtual Character on Mobile Chat Interactions Book Section
In: Proceedings of the 3rd International Conference on Human-Agent Interaction, pp. 105–112, ACM, Daegu, Korea, 2015, ISBN: 978-1-4503-3527-0.
@incollection{kang_effect_2015,
title = {The Effect of An Animated Virtual Character on Mobile Chat Interactions},
author = {Sin-Hwa Kang and Andrew W. Feng and Anton Leuski and Dan Casas and Ari Shapiro},
url = {http://dl.acm.org/citation.cfm?id=2814957},
isbn = {978-1-4503-3527-0},
year = {2015},
date = {2015-10-01},
booktitle = {Proceedings of the 3rd International Conference on Human-Agent Interaction},
pages = {105–112},
publisher = {ACM},
address = {Daegu, Korea},
abstract = {This study explores presentation techniques for a 3D animated chat-based virtual human that communicates engagingly with users. Interactions with the virtual human occur via a smartphone outside of the lab in natural settings. Our work compares the responses of users who interact with no image or a static image of a virtual character as opposed to the animated visage of a virtual human capable of displaying appropriate nonverbal behavior. We further investigate users’ responses to the animated character’s gaze aversion which displayed the character’s act of looking away from users and was presented as a listening behavior. The findings of our study demonstrate that people tend to engage in conversation more by talking for a longer amount of time when they interact with a 3D animated virtual human that averts its gaze, compared to an animated virtual human that does not avert its gaze, a static image of a virtual character, or an audio-only interface.},
keywords = {},
pubstate = {published},
tppubtype = {incollection}
}
This study explores presentation techniques for a 3D animated chat-based virtual human that communicates engagingly with users. Interactions with the virtual human occur via a smartphone outside of the lab in natural settings. Our work compares the responses of users who interact with no image or a static image of a virtual character as opposed to the animated visage of a virtual human capable of displaying appropriate nonverbal behavior. We further investigate users’ responses to the animated character’s gaze aversion which displayed the character’s act of looking away from users and was presented as a listening behavior. The findings of our study demonstrate that people tend to engage in conversation more by talking for a longer amount of time when they interact with a 3D animated virtual human that averts its gaze, compared to an animated virtual human that does not avert its gaze, a static image of a virtual character, or an audio-only interface.
114.
Rizzo, Albert "Skip"; Shilling, Russell; Forbell, Eric; Scherer, Stefan; Gratch, Jonathan; Morency, Louis-Philippe
Autonomous Virtual Human Agents for Healthcare Information Support and Clinical Interviewing Book Section
In: pp. 53–79, Elsevier, Inc., Philadelphia, PA, 2015, ISBN: 978-0-12-420248-1.
@incollection{rizzo_autonomous_2015,
title = {Autonomous Virtual Human Agents for Healthcare Information Support and Clinical Interviewing},
author = {Albert "Skip" Rizzo and Russell Shilling and Eric Forbell and Stefan Scherer and Jonathan Gratch and Louis-Philippe Morency},
url = {http://www.sciencedirect.com/science/article/pii/B9780124202481000039},
isbn = {978-0-12-420248-1},
year = {2015},
date = {2015-10-01},
pages = {53–79},
publisher = {Elsevier, Inc.},
address = {Philadelphia, PA},
abstract = {Over the last 20 years, a virtual revolution has taken place in the use of Virtual Reality simulation technology for clinical purposes. Recent shifts in the social and scientific landscape have now set the stage for the next major movement in Clinical Virtual Reality with the “birth” of intelligent virtual human (VH) agents. Seminal research and development has appeared in the creation of highly interactive, artificially intelligent and natural language capable VHs that can engage real human users in a credible fashion. VHs can now be designed to perceive and act in a virtual world, engage in face-to-face spoken dialogues, and in some cases they are capable of exhibiting human-like emotional reactions. This chapter will detail our applications in this area where a virtual human can provide private online healthcare information and support (i.e., SimCoach) and where a VH can serve the role as a clinical interviewer (i.e., SimSensei).},
keywords = {},
pubstate = {published},
tppubtype = {incollection}
}
Over the last 20 years, a virtual revolution has taken place in the use of Virtual Reality simulation technology for clinical purposes. Recent shifts in the social and scientific landscape have now set the stage for the next major movement in Clinical Virtual Reality with the “birth” of intelligent virtual human (VH) agents. Seminal research and development has appeared in the creation of highly interactive, artificially intelligent and natural language capable VHs that can engage real human users in a credible fashion. VHs can now be designed to perceive and act in a virtual world, engage in face-to-face spoken dialogues, and in some cases they are capable of exhibiting human-like emotional reactions. This chapter will detail our applications in this area where a virtual human can provide private online healthcare information and support (i.e., SimCoach) and where a VH can serve the role as a clinical interviewer (i.e., SimSensei).
115.
Stratou, Giota; Morency, Louis-Philippe; DeVault, David; Hartholt, Arno; Fast, Edward; Lhommet, Margaux; Lucas, Gale; Morbini, Fabrizio; Georgila, Kallirroi; Scherer, Stefan; Gratch, Jonathan; Stacy, Marcella; Traum, David; Rizzo, Albert
A Demonstration of the Perception System in SimSensei, a Virtual Human Application for Healthcare Interviews Proceedings Article
In: Affective Computing and Intelligent Interaction (ACII), 2015 International Conference on, pp. 787–789, IEEE, Xi'an, China, 2015.
@inproceedings{stratou_demonstration_2015,
title = {A Demonstration of the Perception System in SimSensei, a Virtual Human Application for Healthcare Interviews},
author = {Giota Stratou and Louis-Philippe Morency and David DeVault and Arno Hartholt and Edward Fast and Margaux Lhommet and Gale Lucas and Fabrizio Morbini and Kallirroi Georgila and Stefan Scherer and Jonathan Gratch and Marcella Stacy and David Traum and Albert Rizzo},
url = {http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=7344661},
doi = {10.1109/ACII.2015.7344661},
year = {2015},
date = {2015-09-01},
booktitle = {Affective Computing and Intelligent Interaction (ACII), 2015 International Conference on},
pages = {787–789},
publisher = {IEEE},
address = {Xi'an, China},
abstract = {We present the SimSensei system, a fully automatic virtual agent that conducts interviews to assess indicators of psychological distress. With this demo, we focus our attention on the perception part of the system, a multimodal framework which captures and analyzes user state behavior for both behavioral understanding and interactional purposes. We will demonstrate real-time user state sensing as a part of the SimSensei architecture and discuss how this technology enabled automatic analysis of behaviors related to psychological distress.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
We present the SimSensei system, a fully automatic virtual agent that conducts interviews to assess indicators of psychological distress. With this demo, we focus our attention on the perception part of the system, a multimodal framework which captures and analyzes user state behavior for both behavioral understanding and interactional purposes. We will demonstrate real-time user state sensing as a part of the SimSensei architecture and discuss how this technology enabled automatic analysis of behaviors related to psychological distress.
116.
Wang, Ning; Pynadath, David V.; Unnikrishnan, K. V.; Shankar, Santosh; Merchant, Chirag
Intelligent Agents for Virtual Simulation of Human-Robot Interaction Proceedings Article
In: Virtual, Augmented and Mixed Reality, pp. 228 – 239, Springer International Publishing, Los Angeles, CA, 2015, ISBN: 978-3-319-21066-7 978-3-319-21067-4.
@inproceedings{wang_intelligent_2015,
title = {Intelligent Agents for Virtual Simulation of Human-Robot Interaction},
author = {Ning Wang and David V. Pynadath and K. V. Unnikrishnan and Santosh Shankar and Chirag Merchant},
url = {http://ict.usc.edu/pubs/Intelligent%20Agents%20for%20Virtual%20Simulation%20of%20Human-Robot%20Interaction.pdf},
doi = {10.1007/978-3-319-21067-4 24},
isbn = {978-3-319-21066-7 978-3-319-21067-4},
year = {2015},
date = {2015-08-01},
booktitle = {Virtual, Augmented and Mixed Reality},
volume = {9179},
pages = {228 – 239},
publisher = {Springer International Publishing},
address = {Los Angeles, CA},
series = {Lecture Notes in Computer Science},
abstract = {To study how robots can work better with humans as a team, we have designed an agent-based online testbed that supports virtual simulation of domain-independent human-robot interaction. The simulation is implemented as an online game where humans and virtual robots work together in simulated scenarios. This testbed allows researchers to carry out human-robot interaction studies and gain better understanding of, for example, how a robot’s communication can improve human-robot team performance by fostering better trust relationships among humans and their robot teammates. In this paper, we discuss the requirements, challenges and the design of such human-robot simulation. We illustrate its operation with an example human-robot joint reconnaissance task.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
To study how robots can work better with humans as a team, we have designed an agent-based online testbed that supports virtual simulation of domain-independent human-robot interaction. The simulation is implemented as an online game where humans and virtual robots work together in simulated scenarios. This testbed allows researchers to carry out human-robot interaction studies and gain better understanding of, for example, how a robot’s communication can improve human-robot team performance by fostering better trust relationships among humans and their robot teammates. In this paper, we discuss the requirements, challenges and the design of such human-robot simulation. We illustrate its operation with an example human-robot joint reconnaissance task.
117.
Scherer, Stefan; Lucas, Gale; Gratch, Jonathan; Rizzo, Albert; Morency, Louis-Philippe
Self-reported symptoms of depression and PTSD are associated with reduced vowel space in screening interviews Journal Article
In: IEEE Transactions on Affective Computing (in press; doi: 10.1109/TAFFC.2015.2440264), no. 99, 2015, ISSN: 1949-3045.
@article{scherer_self-reported_2015,
title = {Self-reported symptoms of depression and PTSD are associated with reduced vowel space in screening interviews},
author = {Stefan Scherer and Gale Lucas and Jonathan Gratch and Albert Rizzo and Louis-Philippe Morency},
url = {http://ict.usc.edu/pubs/Self-reported%20symptoms%20of%20depression%20and%20PTSD%20are%20associated%20with%20reduced%20vowel%20space%20in%20screening%20interviews.pdf},
doi = {10.1109/TAFFC.2015.2440264},
issn = {1949-3045},
year = {2015},
date = {2015-06-01},
journal = {IEEE Transactions on Affective Computing (in press; doi: 10.1109/TAFFC.2015.2440264)},
number = {99},
abstract = {Reduced frequency range in vowel production is a well documented speech characteristic of individuals with psychological and neurological disorders. Affective disorders such as depression and post-traumatic stress disorder (PTSD) are known to influence motor control and in particular speech production. The assessment and documentation of reduced vowel space and reduced expressivity often either rely on subjective assessments or on analysis of speech under constrained laboratory conditions (e.g. sustained vowel production, reading tasks). These constraints render the analysis of such measures expensive and impractical. Within this work, we investigate an automatic unsupervised machine learning based approach to assess a speaker’s vowel space. Our experiments are based on recordings of 253 individuals. Symptoms of depression and PTSD are assessed using standard self-assessment questionnaires and their cut-off scores. The experiments show a significantly reduced vowel space in subjects that scored positively on the questionnaires. We show the measure’s statistical robustness against varying demographics of individuals and articulation rate. The reduced vowel space for subjects with symptoms of depression can be explained by the common condition of psychomotor retardation influencing articulation and motor control. These findings could potentially support treatment of affective disorders, like depression and PTSD in the future.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Reduced frequency range in vowel production is a well documented speech characteristic of individuals with psychological and neurological disorders. Affective disorders such as depression and post-traumatic stress disorder (PTSD) are known to influence motor control and in particular speech production. The assessment and documentation of reduced vowel space and reduced expressivity often either rely on subjective assessments or on analysis of speech under constrained laboratory conditions (e.g. sustained vowel production, reading tasks). These constraints render the analysis of such measures expensive and impractical. Within this work, we investigate an automatic unsupervised machine learning based approach to assess a speaker’s vowel space. Our experiments are based on recordings of 253 individuals. Symptoms of depression and PTSD are assessed using standard self-assessment questionnaires and their cut-off scores. The experiments show a significantly reduced vowel space in subjects that scored positively on the questionnaires. We show the measure’s statistical robustness against varying demographics of individuals and articulation rate. The reduced vowel space for subjects with symptoms of depression can be explained by the common condition of psychomotor retardation influencing articulation and motor control. These findings could potentially support treatment of affective disorders, like depression and PTSD in the future.
118.
Rizzo, Albert; Cukor, Judith; Gerardi, Maryrose; Alley, Stephanie; Reist, Chris; Roy, Mike; Rothbaum, Barbara O.; Difede, JoAnn
Virtual Reality Exposure for PTSD Due to Military Combat and Terrorist Attacks Journal Article
In: Journal of Contemporary Psychotherapy, pp. 1 –10, 2015, ISSN: 0022-0116, 1573-3564.
@article{rizzo_virtual_2015,
title = {Virtual Reality Exposure for PTSD Due to Military Combat and Terrorist Attacks},
author = {Albert Rizzo and Judith Cukor and Maryrose Gerardi and Stephanie Alley and Chris Reist and Mike Roy and Barbara O. Rothbaum and JoAnn Difede},
url = {http://ict.usc.edu/pubs/Virtual%20Reality%20Exposure%20for%20PTSD%20Due%20to%20Military%20Combat%20and%20Terrorist%20Attacks.pdf},
doi = {10.1007/s10879-015-9306-3},
issn = {0022-0116, 1573-3564},
year = {2015},
date = {2015-05-01},
journal = {Journal of Contemporary Psychotherapy},
pages = {1 –10},
abstract = {Humans exposed to war and terrorist attacks are at risk for the development of posttraumatic stress disorder (PTSD). Numerous reports indicate that the incidence of PTSD in both returning Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) military personnel and survivors of the 9/11 World Trade Center (WTC) attacks is significant. These situations have served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD and other related psychosocial conditions. Virtual reality (VR) delivered exposure therapy for PTSD is currently being used to treat combat and terrorist attack related PTSD with initial reports of positive outcomes. This paper presents an overview and rationale for the use of VR exposure therapy with anxiety disorders and PTSD and describes the status of two systems (Virtual Iraq/Afghanistan and Virtual World Trade Center) developed for this purpose.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Humans exposed to war and terrorist attacks are at risk for the development of posttraumatic stress disorder (PTSD). Numerous reports indicate that the incidence of PTSD in both returning Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) military personnel and survivors of the 9/11 World Trade Center (WTC) attacks is significant. These situations have served to motivate research on how to better develop and disseminate evidence-based treatments for PTSD and other related psychosocial conditions. Virtual reality (VR) delivered exposure therapy for PTSD is currently being used to treat combat and terrorist attack related PTSD with initial reports of positive outcomes. This paper presents an overview and rationale for the use of VR exposure therapy with anxiety disorders and PTSD and describes the status of two systems (Virtual Iraq/Afghanistan and Virtual World Trade Center) developed for this purpose.
119.
Andreatta, Pamela; Klotz, Jessica J.; Madsen, James M.; Hurst, Charles G.; Talbot, Thomas B.
Outcomes From Two Forms of Training for First-Responder Competency in Cholinergic Crisis Management Journal Article
In: Military Medicine, vol. 180, no. 4, pp. 468–474, 2015, ISSN: 0026-4075, 1930-613X.
@article{andreatta_outcomes_2015,
title = {Outcomes From Two Forms of Training for First-Responder Competency in Cholinergic Crisis Management},
author = {Pamela Andreatta and Jessica J. Klotz and James M. Madsen and Charles G. Hurst and Thomas B. Talbot},
url = {http://ict.usc.edu/pubs/Outcomes%20From%20Two%20Forms%20of%20Training%20for%20First-Responder%20Competency%20in%20Cholinergic%20Crisis%20Management.pdf},
doi = {10.7205/MILMED-D-14-00290},
issn = {0026-4075, 1930-613X},
year = {2015},
date = {2015-04-01},
journal = {Military Medicine},
volume = {180},
number = {4},
pages = {468–474},
abstract = {Military and civilian first responders must be able to recognize and effectively manage mass disaster casualties. Clinical management of injuries resulting from nerve agents provides different challenges for first responders than those of conventional weapons. We evaluated the impact of a mixed-methods training program on competency acquisition in cholinergic crisis clinical management using multimedia with either live animal or patient actor examples, and hands-on practice using SimMan3G mannequin simulators. A purposively selected sample of 204 civilian and military first responders who had not previously completed nerve agent training were assessed pre- and post-training for knowledge, performance, self-efficacy, and affective state. We conducted analysis of variance with repeated measures; statistical significance p textbackslashtextbackslashtextless 0.05. Both groups had significant performance improvement across all assessment dimensions: knowledge textbackslashtextbackslashtextgreater 20%, performance textbackslashtextbackslashtextgreater 50%, self-efficacy textbackslashtextbackslashtextgreater 34%, and affective state textbackslashtextbackslashtextgreater 15%. There were no significant differences between the live animal and patient actor groups. These findings could aid in the specification of training for first-responder personnel in military and civilian service. Although less comprehensive than U.S. Army Medical Research Institute of Chemical Defense courses, the training outcomes associated with this easily distributed program demonstrate its value in increasing the competency of first responders in recognizing and managing a mass casualty cholinergic event.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Military and civilian first responders must be able to recognize and effectively manage mass disaster casualties. Clinical management of injuries resulting from nerve agents provides different challenges for first responders than those of conventional weapons. We evaluated the impact of a mixed-methods training program on competency acquisition in cholinergic crisis clinical management using multimedia with either live animal or patient actor examples, and hands-on practice using SimMan3G mannequin simulators. A purposively selected sample of 204 civilian and military first responders who had not previously completed nerve agent training were assessed pre- and post-training for knowledge, performance, self-efficacy, and affective state. We conducted analysis of variance with repeated measures; statistical significance p textbackslashtextbackslashtextless 0.05. Both groups had significant performance improvement across all assessment dimensions: knowledge textbackslashtextbackslashtextgreater 20%, performance textbackslashtextbackslashtextgreater 50%, self-efficacy textbackslashtextbackslashtextgreater 34%, and affective state textbackslashtextbackslashtextgreater 15%. There were no significant differences between the live animal and patient actor groups. These findings could aid in the specification of training for first-responder personnel in military and civilian service. Although less comprehensive than U.S. Army Medical Research Institute of Chemical Defense courses, the training outcomes associated with this easily distributed program demonstrate its value in increasing the competency of first responders in recognizing and managing a mass casualty cholinergic event.
120.
Highland, Krista B.; Costanzo, Michelle E.; Jovanovic, Tanja; Norrholm, Seth D.; Ndiongue, Rochelle B.; Reinhardt, Brian J.; Rothbaum, Barbara; Rizzo, Albert A.; Roy, Michael J.
Catecholamine responses to virtual combat: implications for post-traumatic stress and dimensions of functioning Journal Article
In: Frontiers in Psychology, vol. 6, 2015, ISSN: 1664-1078.
@article{highland_catecholamine_2015,
title = {Catecholamine responses to virtual combat: implications for post-traumatic stress and dimensions of functioning},
author = {Krista B. Highland and Michelle E. Costanzo and Tanja Jovanovic and Seth D. Norrholm and Rochelle B. Ndiongue and Brian J. Reinhardt and Barbara Rothbaum and Albert A. Rizzo and Michael J. Roy},
url = {http://ict.usc.edu/pubs/Catecholamine%20responses%20to%20virtual%20combat%20-%20implications%20for%20post-traumatic%20stress%20and%20dimensions%20of%20functioning.pdf},
doi = {10.3389/fpsyg.2015.00256},
issn = {1664-1078},
year = {2015},
date = {2015-03-01},
journal = {Frontiers in Psychology},
volume = {6},
abstract = {Posttraumatic stress disorder (PTSD) symptoms can result in functional impairment among service members (SMs), even in those without a clinical diagnosis. The variability in outcomes may be related to underlying catecholamine mechanisms. Individuals with PTSD tend to have elevated basal catecholamine levels, though less is known regarding catecholamine responses to trauma-related stimuli. We assessed whether catecholamine responses to a virtual combat environment impact the relationship between PTSD symptom clusters and elements of functioning. Eighty-seven clinically healthy SMs, within 2 months after deployment to Iraq or Afghanistan, completed self-report measures, viewed virtual-reality (VR) combat sequences, and had sequential blood draws. Norepinephrine responses to VR combat exposure moderated the relationship between avoidance symptoms and scales of functioning including physical functioning, physical-role functioning, and vitality. Among those with high levels of avoidance, norepinephrine change was inversely associated with functional status, whereas a positive correlation was observed for those with low levels of avoidance. Our findings represent a novel use of a virtual environment to display combat-related stimuli to returning SMs to elucidate mind-body connections inherent in their responses. The insight gained improves our understanding of post-deployment symptoms and quality of life in SMs and may facilitate enhancements in treatment. Further research is needed to validate these findings in other populations and to define the implications for treatment effectiveness.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Posttraumatic stress disorder (PTSD) symptoms can result in functional impairment among service members (SMs), even in those without a clinical diagnosis. The variability in outcomes may be related to underlying catecholamine mechanisms. Individuals with PTSD tend to have elevated basal catecholamine levels, though less is known regarding catecholamine responses to trauma-related stimuli. We assessed whether catecholamine responses to a virtual combat environment impact the relationship between PTSD symptom clusters and elements of functioning. Eighty-seven clinically healthy SMs, within 2 months after deployment to Iraq or Afghanistan, completed self-report measures, viewed virtual-reality (VR) combat sequences, and had sequential blood draws. Norepinephrine responses to VR combat exposure moderated the relationship between avoidance symptoms and scales of functioning including physical functioning, physical-role functioning, and vitality. Among those with high levels of avoidance, norepinephrine change was inversely associated with functional status, whereas a positive correlation was observed for those with low levels of avoidance. Our findings represent a novel use of a virtual environment to display combat-related stimuli to returning SMs to elucidate mind-body connections inherent in their responses. The insight gained improves our understanding of post-deployment symptoms and quality of life in SMs and may facilitate enhancements in treatment. Further research is needed to validate these findings in other populations and to define the implications for treatment effectiveness.
Filter
2007
Kenny, Patrick G.; Parsons, Thomas D.; Gratch, Jonathan; Leuski, Anton; Rizzo, Albert
Virtual Patients for Clinical Therapist Skills Training Proceedings Article
In: Lecture Notes in Artificial Intelligence; Proceedings of the 7th International Conference on Intelligent Virtual Agents (IVA), pp. 197–210, Paris, France, 2007.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@inproceedings{kenny_virtual_2007-1,
title = {Virtual Patients for Clinical Therapist Skills Training},
author = {Patrick G. Kenny and Thomas D. Parsons and Jonathan Gratch and Anton Leuski and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Virtual%20Patients%20for%20Clinical%20Therapist%20Skills%20Training.pdf},
year = {2007},
date = {2007-01-01},
booktitle = {Lecture Notes in Artificial Intelligence; Proceedings of the 7th International Conference on Intelligent Virtual Agents (IVA)},
volume = {4722},
pages = {197–210},
address = {Paris, France},
abstract = {Virtual humans offer an exciting and powerful potential for rich interactive experiences. Fully embodied virtual humans are growing in capability, ease, and utility. As a result, they present an opportunity for expanding research into burgeoning virtual patient medical applications. In this paper we consider the ways in which one may go about building and applying virtual human technology to the virtual patient domain. Specifically we aim to show that virtual human technology may be used to help develop the interviewing and diagnostics skills of developing clinicians. Herein we proffer a description of our iterative design process and preliminary results to show that virtual patients may be a useful adjunct to psychotherapy education.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {inproceedings}
}
Virtual humans offer an exciting and powerful potential for rich interactive experiences. Fully embodied virtual humans are growing in capability, ease, and utility. As a result, they present an opportunity for expanding research into burgeoning virtual patient medical applications. In this paper we consider the ways in which one may go about building and applying virtual human technology to the virtual patient domain. Specifically we aim to show that virtual human technology may be used to help develop the interviewing and diagnostics skills of developing clinicians. Herein we proffer a description of our iterative design process and preliminary results to show that virtual patients may be a useful adjunct to psychotherapy education.
Parsons, Thomas D.; Bowerly, Todd; Buckwalter, John Galen; Rizzo, Albert
In: Child Neuropsychology, vol. 13, pp. 363–381, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_controlled_2007,
title = {A controlled clinical comparison of attention performance in children with ADHD in a virtual reality classroom compared to standard neuropsychological methods},
author = {Thomas D. Parsons and Todd Bowerly and John Galen Buckwalter and Albert Rizzo},
url = {http://ict.usc.edu/pubs/A%20CONTROLLED%20CLINICAL%20COMPARISON%20OF%20ATTENTION%20PERFORMANCE%20IN%20CHILDREN%20WITH%20ADHD%20IN%20A%20VIRTUAL%20REALITY%20CLASSROOM%20COMPARED%20TO%20STANDARD%20NEUROPSYCHOLOGICAL%20METHODS.pdf},
doi = {10.1080/13825580600943473},
year = {2007},
date = {2007-01-01},
journal = {Child Neuropsychology},
volume = {13},
pages = {363–381},
abstract = {In this initial pilot study, a controlled clinical comparison was made of attention performance in children with attention deficit-hyperactivity disorder (ADHD) in a virtual reality (VR) classroom. Ten boys diagnosed with ADHD and ten normal control boys participated in the study. Groups did not significantly differ in mean age, grade level, ethnicity, or handedness. No participants reported simulator sickness following VR exposure. Children with ADHD exhibited more omission errors, commission errors, and overall body movement than normal control children in the VR classroom. Children with ADHD were more impacted by distraction in the VR classroom. VR classroom measures were correlated with traditional ADHD assessment tools and the flatscreen CPT. Of note, the small sample size incorporated in each group and higher WISC-III scores of normal controls might have some bearing on the overall interpretation of results. These data suggested that the Virtual Classroom had good potential for controlled performance assessment within an ecologically valid environment and appeared to parse out significant effects due to the presence of distraction stimuli.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
In this initial pilot study, a controlled clinical comparison was made of attention performance in children with attention deficit-hyperactivity disorder (ADHD) in a virtual reality (VR) classroom. Ten boys diagnosed with ADHD and ten normal control boys participated in the study. Groups did not significantly differ in mean age, grade level, ethnicity, or handedness. No participants reported simulator sickness following VR exposure. Children with ADHD exhibited more omission errors, commission errors, and overall body movement than normal control children in the VR classroom. Children with ADHD were more impacted by distraction in the VR classroom. VR classroom measures were correlated with traditional ADHD assessment tools and the flatscreen CPT. Of note, the small sample size incorporated in each group and higher WISC-III scores of normal controls might have some bearing on the overall interpretation of results. These data suggested that the Virtual Classroom had good potential for controlled performance assessment within an ecologically valid environment and appeared to parse out significant effects due to the presence of distraction stimuli.
Miller, Karen J.; Parsons, Thomas D.; Whybrow, Peter C.; Herle, Katja; Rasgon, Natalie; Herle, Andre; Martinez, Dorothy; Silverman, Dan H.; Bauer, Michael
Verbal Memory Retrieval Deficits Associated With Untreated Hypothyroidism Journal Article
In: Journal of Neuropsychiatry and Clinical Neurosciences, vol. 19, no. 2, pp. 132–136, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{miller_verbal_2007,
title = {Verbal Memory Retrieval Deficits Associated With Untreated Hypothyroidism},
author = {Karen J. Miller and Thomas D. Parsons and Peter C. Whybrow and Katja Herle and Natalie Rasgon and Andre Herle and Dorothy Martinez and Dan H. Silverman and Michael Bauer},
url = {http://ict.usc.edu/pubs/Verbal%20Memory%20Retrieval%20Deficits%20Associated%20With%20Untreated%20Hypothyroidism.pdf},
year = {2007},
date = {2007-01-01},
journal = {Journal of Neuropsychiatry and Clinical Neurosciences},
volume = {19},
number = {2},
pages = {132–136},
abstract = {The effects of inadequate thyroid hormone availability to the brain on adult cognitive function are poorly understood. This study assessed the effects of hypothyroidism on cognitive function using a standard neuropsychological battery in 14 patients suffering from untreated hypothyroidism and complaining of subjective cognitive difï¬culties in comparison with 10 age-matched healthy comparison subjects. Signiï¬cant differences between groups were limited to verbal memory retrieval as measured by the California Verbal Learning Test (CVLT). On short delay free recall, long delay free recall, and long delay cued recall, signiï¬cant differences remained between groups despite the limited statistical power of this study. There were no signiï¬cant results found between groups on attentional or nonverbal tasks. Results suggest that hypothyroid-related memory deï¬cits are not attributable to an attentional deï¬cit but rather to speciï¬c retrieval deï¬cits.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The effects of inadequate thyroid hormone availability to the brain on adult cognitive function are poorly understood. This study assessed the effects of hypothyroidism on cognitive function using a standard neuropsychological battery in 14 patients suffering from untreated hypothyroidism and complaining of subjective cognitive difï¬culties in comparison with 10 age-matched healthy comparison subjects. Signiï¬cant differences between groups were limited to verbal memory retrieval as measured by the California Verbal Learning Test (CVLT). On short delay free recall, long delay free recall, and long delay cued recall, signiï¬cant differences remained between groups despite the limited statistical power of this study. There were no signiï¬cant results found between groups on attentional or nonverbal tasks. Results suggest that hypothyroid-related memory deï¬cits are not attributable to an attentional deï¬cit but rather to speciï¬c retrieval deï¬cits.
Robertson, R. Kevin; Parsons, Thomas D.; Rogers, Steven A.; Braaten, Alyssa J.; Robertson, Wendy T.; Wilson, Susan; Hall, Colin D.
Assessing health-related quality of life in NeuroAIDS: some psychometric properties of the Neurological Quality of Life Questionnaire (NeuroQOL) Journal Article
In: Journal of Clinical Neuroscience, vol. 14, pp. 416+423, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{robertson_assessing_2007,
title = {Assessing health-related quality of life in NeuroAIDS: some psychometric properties of the Neurological Quality of Life Questionnaire (NeuroQOL)},
author = {R. Kevin Robertson and Thomas D. Parsons and Steven A. Rogers and Alyssa J. Braaten and Wendy T. Robertson and Susan Wilson and Colin D. Hall},
url = {http://ict.usc.edu/pubs/Assessing%20health-related%20quality%20of%20life%20in%20NeuroAIDS-%20some%20psychometric%20properties%20of%20the%20Neurological%20Quality%20of%20Life%20Questionnaire%20(NeuroQOL).pdf},
year = {2007},
date = {2007-01-01},
journal = {Journal of Clinical Neuroscience},
volume = {14},
pages = {416+423},
abstract = {Several studies were undertaken to assess the psychometric properties (reliability and initial convergent and discriminant construct validity) of the Neurological Quality of Life Questionnaire (NeuroQOL). The NeuroQOL contains 114 items answered in self report Likert format, with higher scores reflecting better quality of life. Study one compared the questionnaire with existing quality of life measures (Symptom Distress Scale, Sickness Impact Profile) and disease stage, psychological, neuropsychological and neurological measures, and a significant correlation was also fount with each domain. The internal consistency reliability (alpha = 0.96), split half reliability (r12 = 0.97), and test-retest reliability (coefficients were 0.78 for 6 months and 0.67 for one year intervals between test and retest) were all found to high and adequately stable. Overall, these results indicate acceptable reliability and initial construct valididty for the NeuroQOL.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Several studies were undertaken to assess the psychometric properties (reliability and initial convergent and discriminant construct validity) of the Neurological Quality of Life Questionnaire (NeuroQOL). The NeuroQOL contains 114 items answered in self report Likert format, with higher scores reflecting better quality of life. Study one compared the questionnaire with existing quality of life measures (Symptom Distress Scale, Sickness Impact Profile) and disease stage, psychological, neuropsychological and neurological measures, and a significant correlation was also fount with each domain. The internal consistency reliability (alpha = 0.96), split half reliability (r12 = 0.97), and test-retest reliability (coefficients were 0.78 for 6 months and 0.67 for one year intervals between test and retest) were all found to high and adequately stable. Overall, these results indicate acceptable reliability and initial construct valididty for the NeuroQOL.
Rizzo, Albert; Graap, Ken; McLay, Robert N.; Perlman, Karen; Rothbaum, Barbara O.; Reger, Greg; Parsons, Thomas D.; Difede, JoAnn; Pair, Jarrell
Virtual Iraq: Initial Case Reports from a VR Exposure Therapy Application for Combat-Related Post Traumatic Stress Disorder Journal Article
In: Virtual Rehabilitation, vol. 27, pp. 124–130, 2007.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@article{rizzo_virtual_2007,
title = {Virtual Iraq: Initial Case Reports from a VR Exposure Therapy Application for Combat-Related Post Traumatic Stress Disorder},
author = {Albert Rizzo and Ken Graap and Robert N. McLay and Karen Perlman and Barbara O. Rothbaum and Greg Reger and Thomas D. Parsons and JoAnn Difede and Jarrell Pair},
url = {http://ict.usc.edu/pubs/Virtual%20Iraq-%20Initial%20Case%20Reports%20from%20a%20VR%20Exposure%20Therapy%20Application%20for%20Combat-Related%20Post%20Traumatic%20Stress%20Disorder.pdf},
year = {2007},
date = {2007-01-01},
journal = {Virtual Rehabilitation},
volume = {27},
pages = {124–130},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale and brief description of a Virtual Iraq PTSD VR therapy application and present initial findings from two successfully treated patients. The VR treatment environment was created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far, Virtual Iraq consists of a series of customizable virtual scenarios designed to represent relevant Middle Eastern VR contexts for exposure therapy, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system deployed in Iraq and tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center and the results from two successfully treated patients are presented along with a delineation of our future plans for research and clinical care using this application.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {article}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale and brief description of a Virtual Iraq PTSD VR therapy application and present initial findings from two successfully treated patients. The VR treatment environment was created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far, Virtual Iraq consists of a series of customizable virtual scenarios designed to represent relevant Middle Eastern VR contexts for exposure therapy, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system deployed in Iraq and tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center and the results from two successfully treated patients are presented along with a delineation of our future plans for research and clinical care using this application.
Parsons, Thomas D.; Rizzo, Albert; Bamattre, Jacob; Brennan, John
Virtual Reality Cognitive Performance Assessment Test Journal Article
In: Annual Review of CyberTherapy and Telemedicine, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_virtual_2007,
title = {Virtual Reality Cognitive Performance Assessment Test},
author = {Thomas D. Parsons and Albert Rizzo and Jacob Bamattre and John Brennan},
url = {http://ict.usc.edu/pubs/Virtual%20Reality%20Cognitive%20Performance%20Assessment%20Test.pdf},
year = {2007},
date = {2007-01-01},
journal = {Annual Review of CyberTherapy and Telemedicine},
abstract = {Virtual Reality Cognitive Performance Assessment Test (VRCPAT) is a virtual environment based measure of learning and memory. We examined convergent and discriminant validity and hypothesized that the VRCPAT’s Total Learning and Memory scores would correlate with other neuropsychological measures involving learning and memory, but not with measures involving potential confounds (i.e., Executive Functions; Attention; and Processing Speed). Using a sequential hierarchical strategy, each stage of test development did not proceed until specified criteria were met. The 15 minute VRCPAT battery and a 1.5 hour in-person neuropsychological assessment were conducted with a randomly selected sample of 20 healthy adults that included equivalent distributions of men and women from ethnically diverse populations. Results supported both convergent and discriminant validity. That is, findings suggest that the VRCPAT measures a capacity that is 1) consistent with that assessed by traditional paper and pencil measures involving learning and memory; and 2) inconsistent with that assessed by traditional paper and pencil measures assessing neurocognitive domains traditionally assumed to be other than learning and memory. We conclude that the VRCPAT is a valid test that provides a unique opportunity to reliably and efficiently study memory function within an ecologically valid environment.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Virtual Reality Cognitive Performance Assessment Test (VRCPAT) is a virtual environment based measure of learning and memory. We examined convergent and discriminant validity and hypothesized that the VRCPAT’s Total Learning and Memory scores would correlate with other neuropsychological measures involving learning and memory, but not with measures involving potential confounds (i.e., Executive Functions; Attention; and Processing Speed). Using a sequential hierarchical strategy, each stage of test development did not proceed until specified criteria were met. The 15 minute VRCPAT battery and a 1.5 hour in-person neuropsychological assessment were conducted with a randomly selected sample of 20 healthy adults that included equivalent distributions of men and women from ethnically diverse populations. Results supported both convergent and discriminant validity. That is, findings suggest that the VRCPAT measures a capacity that is 1) consistent with that assessed by traditional paper and pencil measures involving learning and memory; and 2) inconsistent with that assessed by traditional paper and pencil measures assessing neurocognitive domains traditionally assumed to be other than learning and memory. We conclude that the VRCPAT is a valid test that provides a unique opportunity to reliably and efficiently study memory function within an ecologically valid environment.
Parsons, Thomas D.; Rogers, Steven A.; Hall, Colin D.; Robertson, R. Kevin
Motor Based Assessment of Neurocognitive Functioning in Resource-Limited International Settings. Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 29, pp. 59–66, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_motor_2007,
title = {Motor Based Assessment of Neurocognitive Functioning in Resource-Limited International Settings.},
author = {Thomas D. Parsons and Steven A. Rogers and Colin D. Hall and R. Kevin Robertson},
url = {http://ict.usc.edu/pubs/Motor%20based%20assessment%20of%20neurocognitive%20functioning%20in%20resource-limited%20Iinternational%20settings.pdf},
year = {2007},
date = {2007-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {29},
pages = {59–66},
abstract = {This study compared variance accounted for by neuropsychological tests in both a brief motor battery and in a comprehensive neuropsychological battery. 327 HIV + subjects received a comprehensive cognitive battery and a shorter battery (Timed Gait, Grooved Pegboard, and Fingertapping). A significant correlation existed between the motor component tests and the more comprehensive battery (52% of variance). Adding Digit symbol and Trailmaking increased the amount of variance accounted for (73%). Motor battery sensitivity to impairment diagnosis was 0.79 and specificity was 0.76. A motor battery may have broader utility to diagnose and monitor HIV related neurocognitive disorders in international settings.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
This study compared variance accounted for by neuropsychological tests in both a brief motor battery and in a comprehensive neuropsychological battery. 327 HIV + subjects received a comprehensive cognitive battery and a shorter battery (Timed Gait, Grooved Pegboard, and Fingertapping). A significant correlation existed between the motor component tests and the more comprehensive battery (52% of variance). Adding Digit symbol and Trailmaking increased the amount of variance accounted for (73%). Motor battery sensitivity to impairment diagnosis was 0.79 and specificity was 0.76. A motor battery may have broader utility to diagnose and monitor HIV related neurocognitive disorders in international settings.
Iudicello, Jennifer E.; Woods, Steven Paul; Parsons, Thomas D.; Moran, Lisa M.; Carey, Catherine L.; Grant, Igor
Verbal fluency in HIV infection: A meta-analytic review Journal Article
In: Journal of the International Neuropsychological Society, vol. 13, pp. 183–189, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{iudicello_verbal_2007,
title = {Verbal fluency in HIV infection: A meta-analytic review},
author = {Jennifer E. Iudicello and Steven Paul Woods and Thomas D. Parsons and Lisa M. Moran and Catherine L. Carey and Igor Grant},
url = {http://ict.usc.edu/pubs/Verbal%20fluency%20in%20HIV%20infection-%20A%20meta-analytic%20review.pdf},
doi = {10.10170S1355617707070221},
year = {2007},
date = {2007-01-01},
journal = {Journal of the International Neuropsychological Society},
volume = {13},
pages = {183–189},
abstract = {Given the largely prefrontostriatal neuropathogenesis of HIV-associated neurobehavioral deficits, it is often presumed that HIV infection leads to greater impairment on letter versus category fluency. A meta-analysis of the HIV verbal fluency literature was conducted (k 5 37, n 5 7110) to assess this hypothesis and revealed generally small effect sizes for both letter and category fluency, which increased in magnitude with advancing HIV disease severity. Across all studies, the mean effect size of category fluency was slightly larger than that of letter fluency. However, the discrepancy between category and letter fluency dissipated in a more conservative analysis of only those studies that included both tests. Thus, HIV-associated impairments in letter and category fluency are of similar magnitude, suggesting that mild word generation deficits are evident in HIV, regardless of whether traditional letter or semantic cues are used to guide the word search and retrieval process.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Given the largely prefrontostriatal neuropathogenesis of HIV-associated neurobehavioral deficits, it is often presumed that HIV infection leads to greater impairment on letter versus category fluency. A meta-analysis of the HIV verbal fluency literature was conducted (k 5 37, n 5 7110) to assess this hypothesis and revealed generally small effect sizes for both letter and category fluency, which increased in magnitude with advancing HIV disease severity. Across all studies, the mean effect size of category fluency was slightly larger than that of letter fluency. However, the discrepancy between category and letter fluency dissipated in a more conservative analysis of only those studies that included both tests. Thus, HIV-associated impairments in letter and category fluency are of similar magnitude, suggesting that mild word generation deficits are evident in HIV, regardless of whether traditional letter or semantic cues are used to guide the word search and retrieval process.
Macedonio, Mary F.; Parsons, Thomas D.; Digiuseppe, Raymond A.; Wiederhold, Brenda K.; Rizzo, Albert
Immersiveness and Physiological Arousal within Panoramic Video-Based Virtual Reality Journal Article
In: CyberPsychology and Behavior, vol. 10, no. 4, pp. 508–515, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{macedonio_immersiveness_2007,
title = {Immersiveness and Physiological Arousal within Panoramic Video-Based Virtual Reality},
author = {Mary F. Macedonio and Thomas D. Parsons and Raymond A. Digiuseppe and Brenda K. Wiederhold and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Immersiveness%20and%20Physiological%20Arousal%20within%20Panoramic%20Video-Based%20Virtual%20Reality.pdf},
year = {2007},
date = {2007-01-01},
journal = {CyberPsychology and Behavior},
volume = {10},
number = {4},
pages = {508–515},
abstract = {In this paper, we discuss findings from a study that used panoramic video-based virtual environments (PVVEs) to induce self-reported anger. The study assessed "immersiveness" and physiological correlates of anger arousal (i.e., heart rate, blood pressure, galvanic skin response [GSR], respiration, and skin temperature). Results indicate that over time, panoramic video-based virtual scenarios can be, at the very least, physiologically arousing. Further, it can be affirmed from the results that hypnotizability, as defined by the applied measures, interacts with group on physiological arousal measures. Hence, physiological arousal appeared to be moderated by participant hypnotizability and absorption levels.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
In this paper, we discuss findings from a study that used panoramic video-based virtual environments (PVVEs) to induce self-reported anger. The study assessed "immersiveness" and physiological correlates of anger arousal (i.e., heart rate, blood pressure, galvanic skin response [GSR], respiration, and skin temperature). Results indicate that over time, panoramic video-based virtual scenarios can be, at the very least, physiologically arousing. Further, it can be affirmed from the results that hypnotizability, as defined by the applied measures, interacts with group on physiological arousal measures. Hence, physiological arousal appeared to be moderated by participant hypnotizability and absorption levels.
Buckwalter, John Galen; Geiger, A. M.; Parsons, Thomas D.; Handler, J.; Howes, J.; Lehmer, R. R.
Cognitive Effects of Short-term Use of Raloxifene: A Randomized Clinical Trial Journal Article
In: International Journal of Neuroscience, vol. 117, pp. 1579–1590, 2007.
Abstract | Links | BibTeX | Tags: MedVR
@article{buckwalter_cognitive_2007,
title = {Cognitive Effects of Short-term Use of Raloxifene: A Randomized Clinical Trial},
author = {John Galen Buckwalter and A. M. Geiger and Thomas D. Parsons and J. Handler and J. Howes and R. R. Lehmer},
url = {http://ict.usc.edu/pubs/Cognitive%20Effects%20of%20Short-term%20Use%20of%20Raloxifene-%20A%20Randomized%20Clinical%20Trial.pdf},
year = {2007},
date = {2007-01-01},
journal = {International Journal of Neuroscience},
volume = {117},
pages = {1579–1590},
abstract = {Two questions regarding findings from the Women's Health Initiative are (1) What is the effect of various hormonal regimens including selective estrogen receptor modulators? and (2) Is the negative effect on cognitive functioning related to the older age (65+years) if the women? This study addresses these two questions in a short-term randomized trial of the effects of raloxifene versus alendronate on cognition. The study found only one significant interaction where the raloxifene and alendronate group changed differently across the two testing occasions. Hence, raloxifene does not have any impact, positive or negative, on short-term cognitive functioning when compared to alendronate.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Two questions regarding findings from the Women's Health Initiative are (1) What is the effect of various hormonal regimens including selective estrogen receptor modulators? and (2) Is the negative effect on cognitive functioning related to the older age (65+years) if the women? This study addresses these two questions in a short-term randomized trial of the effects of raloxifene versus alendronate on cognition. The study found only one significant interaction where the raloxifene and alendronate group changed differently across the two testing occasions. Hence, raloxifene does not have any impact, positive or negative, on short-term cognitive functioning when compared to alendronate.
Robertson, R. Kevin; Smurzynski, Marlene; Parsons, Thomas D.; Wu, Kunling; Bosch, Ronald J.; Wu, Julia; McArthur, Justin C.; Collier, Ann C.; Evans, Scott R.; Ellis, Ron J.
The Prevalence and Incidence of Neurocognitive Impairment in the HAART Era Journal Article
In: AIDS, vol. 21, pp. 1915–1921, 2007, ISSN: 0269-9370.
Abstract | Links | BibTeX | Tags: MedVR
@article{robertson_prevalence_2007,
title = {The Prevalence and Incidence of Neurocognitive Impairment in the HAART Era},
author = {R. Kevin Robertson and Marlene Smurzynski and Thomas D. Parsons and Kunling Wu and Ronald J. Bosch and Julia Wu and Justin C. McArthur and Ann C. Collier and Scott R. Evans and Ron J. Ellis},
url = {http://ict.usc.edu/pubs/The%20prevalence%20and%20incidence%20of%20neurocognitive%20impairment%20in%20the%20HAART%20era.pdf},
issn = {0269-9370},
year = {2007},
date = {2007-01-01},
journal = {AIDS},
volume = {21},
pages = {1915–1921},
abstract = {Objectives: HAART suppresses HIV viral replication and restores immune function. The effects of HAART on neurological disease are less well understood. The aim of this study was to assess the prevalence and incidence of neurocognitive impairment in individuals who initiated HAART as part of an AIDS clinical trial. Design: A prospective cohort study of HIV-positive patients enrolled in randomized antiretroviral trials, the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) study. Methods: We examined the association between baseline and demographic characteristics and neurocognitive impairment among 1160 subjects enrolled in the ALLRT study. Results: A history of immunosuppression (nadir CD4 cell count textbackslashtextbackslashtextbackslashtextbackslashtextless 200 cells/ml) was associated with an increase in prevalent neurocognitive impairment. There were no signiï¬cant virological and immunological predictors of incident neurocognitive impairment. Current immune status (low CD4 cell count) was associated with sustained prevalent impairment. Conclusion: The association of previous advanced immunosuppression with prevalent and sustained impairment suggests that there is a non-reversible component of neural injury that tracks with a history of disease progression. The association of sustained impairment with worse current immune status (low CD4 cell count) suggests that restoring immunocompetence increases the likelihood of neurocognitive recovery. Finally, the lack of association between incident neurocognitive impairment and virological and immunological indicators implies that neural injury continues in some patients regardless of the success of antiretroviral therapy on these laboratory measures.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Objectives: HAART suppresses HIV viral replication and restores immune function. The effects of HAART on neurological disease are less well understood. The aim of this study was to assess the prevalence and incidence of neurocognitive impairment in individuals who initiated HAART as part of an AIDS clinical trial. Design: A prospective cohort study of HIV-positive patients enrolled in randomized antiretroviral trials, the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) study. Methods: We examined the association between baseline and demographic characteristics and neurocognitive impairment among 1160 subjects enrolled in the ALLRT study. Results: A history of immunosuppression (nadir CD4 cell count textbackslashtextbackslashtextbackslashtextbackslashtextless 200 cells/ml) was associated with an increase in prevalent neurocognitive impairment. There were no signiï¬cant virological and immunological predictors of incident neurocognitive impairment. Current immune status (low CD4 cell count) was associated with sustained prevalent impairment. Conclusion: The association of previous advanced immunosuppression with prevalent and sustained impairment suggests that there is a non-reversible component of neural injury that tracks with a history of disease progression. The association of sustained impairment with worse current immune status (low CD4 cell count) suggests that restoring immunocompetence increases the likelihood of neurocognitive recovery. Finally, the lack of association between incident neurocognitive impairment and virological and immunological indicators implies that neural injury continues in some patients regardless of the success of antiretroviral therapy on these laboratory measures.
2006
Rizzo, Albert; Pair, Jarrell; Parsons, Thomas D.; Liewer, Matt; Graap, Ken; Difede, JoAnn; Rothbaum, Barbara O.; Reger, Greg; Roy, Michael
A Virtual Reality Therapy Application for OEF/OIF Combat-related Post Traumatic Stress Disorder Proceedings Article
In: Proceedings of the 25th Army Science Conference, Orlando, FL, 2006.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@inproceedings{rizzo_virtual_2006-1,
title = {A Virtual Reality Therapy Application for OEF/OIF Combat-related Post Traumatic Stress Disorder},
author = {Albert Rizzo and Jarrell Pair and Thomas D. Parsons and Matt Liewer and Ken Graap and JoAnn Difede and Barbara O. Rothbaum and Greg Reger and Michael Roy},
url = {http://ict.usc.edu/pubs/A%20VIRTUAL%20REALITY%20THERAPY%20APPLICATION%20FOR%20OEF%20OIF%20COMBAT-RELATED%20POST%20TRAUMATIC%20STRESS%20DISORDER.pdf},
year = {2006},
date = {2006-11-01},
booktitle = {Proceedings of the 25th Army Science Conference},
address = {Orlando, FL},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system in Iraq tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center. Other sites are preparing to use the application for a variety of PTSD and VR research purposes.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system in Iraq tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center. Other sites are preparing to use the application for a variety of PTSD and VR research purposes.
Marsella, Stacy C.; Carnicke, Sharon Marie; Gratch, Jonathan; Okhmatovskaia, Anna; Rizzo, Albert
An Exploration of Delsartes Structural Acting System Proceedings Article
In: Proceedings of the 6th International Conference on Intelligent Virtual Agents (IVA), pp. 80–92, Marina del Rey, CA, 2006.
Abstract | Links | BibTeX | Tags: MedVR, Social Simulation, Virtual Humans
@inproceedings{marsella_exploration_2006,
title = {An Exploration of Delsartes Structural Acting System},
author = {Stacy C. Marsella and Sharon Marie Carnicke and Jonathan Gratch and Anna Okhmatovskaia and Albert Rizzo},
url = {http://ict.usc.edu/pubs/An%20Exploration%20of%20Delsarte%E2%80%99s%20Structural%20Acting%20System.pdf},
year = {2006},
date = {2006-08-01},
booktitle = {Proceedings of the 6th International Conference on Intelligent Virtual Agents (IVA)},
pages = {80–92},
address = {Marina del Rey, CA},
abstract = {The designers of virtual agents often draw on a large research literature in psychology, linguistics and human ethology to design embodied agents that can interact with people. In this paper, we consider a structural acting system developed by Francois Delsarte as a possible resource in designing the nonverbal behavior of embodied agents. Using human subjects,we evaluate one component of the system, Delsarte's Cube, that addresses the meaning of differing attitudes of the hand in gestures.},
keywords = {MedVR, Social Simulation, Virtual Humans},
pubstate = {published},
tppubtype = {inproceedings}
}
The designers of virtual agents often draw on a large research literature in psychology, linguistics and human ethology to design embodied agents that can interact with people. In this paper, we consider a structural acting system developed by Francois Delsarte as a possible resource in designing the nonverbal behavior of embodied agents. Using human subjects,we evaluate one component of the system, Delsarte's Cube, that addresses the meaning of differing attitudes of the hand in gestures.
Parsons, Thomas D.; Rogers, Steven A.; Braaten, Alyssa J.; Woods, Steven Paul; Tröster, Alexander I.
Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis Journal Article
In: Lancet Neurology, vol. 5, pp. 578–588, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_cognitive_2006,
title = {Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis},
author = {Thomas D. Parsons and Steven A. Rogers and Alyssa J. Braaten and Steven Paul Woods and Alexander I. Tröster},
url = {http://ict.usc.edu/pubs/Cognitive%20sequelae%20of%20subthalamic%20nucleus%20deep%20brain%20stimulation%20in%20Parkinson%E2%80%99s%20disease-%20a%20meta-analysis.pdf},
year = {2006},
date = {2006-06-01},
journal = {Lancet Neurology},
volume = {5},
pages = {578–588},
abstract = {Summary: Background Deep brain stimulation of the subthalamic nucleus (STN DBS) is an increasingly common treatment for Parkinson's disease. Qualitative reviews have concluded that diminished verbal fluency is common after STN DBS, but that changes in global cognitive abilities, attention, executive functions, and memory are only inconsistently observed and, when present, often nominal or transient. We did a quantitative meta-analysis to improve understanding of the variability and clinical signiï¬cance of cognitive dysfunction after STN DBS. Methods: We searched MedLine, PsycLIT, and ISI Web of Science electronic databases for articles published between 1990 and 2006, and extracted information about number of patients, exclusion criteria, conï¬rmation of target by microelectrode recording, veriï¬cation of electrode placement via radiographic means, stimulation parameters, assessment time points, assessment measures, whether patients were on levodopa or dopaminomimetics, and summary statistics needed for computation of effect sizes. We used the random-effects meta-analytical model to assess continuous outcomes before and after STN DBS. Findings: Of 40 neuropsychological studies identiï¬ed, 28 cohort studies (including 612 patients) were eligible for inclusion in the meta-analysis. After adjusting for heterogeneity of variance in study effect sizes, the random effects meta-analysis revealed signiï¬cant, albeit small, declines in executive functions and verbal learning and memory. Moderate declines were only reported in semantic (Cohen's d 0·73) and phonemic verbal fluency (0·51). Changes in verbal fluency were not related to patient age, disease duration, stimulation parameters, or change in dopaminomimetic dose after surgery. Interpretation: STN DBS, in selected patients, seems relatively safe from a cognitive standpoint. However, diffculty in identiï¬cation of factors underlying changes in verbal fluency draws attention to the need for uniform and detailed reporting of patient selection, demographic, disease, treatment, surgical, stimulation, and clinical outcome parameters.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Summary: Background Deep brain stimulation of the subthalamic nucleus (STN DBS) is an increasingly common treatment for Parkinson's disease. Qualitative reviews have concluded that diminished verbal fluency is common after STN DBS, but that changes in global cognitive abilities, attention, executive functions, and memory are only inconsistently observed and, when present, often nominal or transient. We did a quantitative meta-analysis to improve understanding of the variability and clinical signiï¬cance of cognitive dysfunction after STN DBS. Methods: We searched MedLine, PsycLIT, and ISI Web of Science electronic databases for articles published between 1990 and 2006, and extracted information about number of patients, exclusion criteria, conï¬rmation of target by microelectrode recording, veriï¬cation of electrode placement via radiographic means, stimulation parameters, assessment time points, assessment measures, whether patients were on levodopa or dopaminomimetics, and summary statistics needed for computation of effect sizes. We used the random-effects meta-analytical model to assess continuous outcomes before and after STN DBS. Findings: Of 40 neuropsychological studies identiï¬ed, 28 cohort studies (including 612 patients) were eligible for inclusion in the meta-analysis. After adjusting for heterogeneity of variance in study effect sizes, the random effects meta-analysis revealed signiï¬cant, albeit small, declines in executive functions and verbal learning and memory. Moderate declines were only reported in semantic (Cohen's d 0·73) and phonemic verbal fluency (0·51). Changes in verbal fluency were not related to patient age, disease duration, stimulation parameters, or change in dopaminomimetic dose after surgery. Interpretation: STN DBS, in selected patients, seems relatively safe from a cognitive standpoint. However, diffculty in identiï¬cation of factors underlying changes in verbal fluency draws attention to the need for uniform and detailed reporting of patient selection, demographic, disease, treatment, surgical, stimulation, and clinical outcome parameters.
Parsons, Thomas D.; Tucker, Karen A.; Hall, Colin D.; Robertson, Wendy T.; Eron, Joseph J.; Fried, Michael W.; Robertson, R. Kevin
Neurocognitive functioning and HAART in HIV and hepatitis C virus co-infection Journal Article
In: AIDS, vol. 20, pp. 1591–1595, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_neurocognitive_2006,
title = {Neurocognitive functioning and HAART in HIV and hepatitis C virus co-infection},
author = {Thomas D. Parsons and Karen A. Tucker and Colin D. Hall and Wendy T. Robertson and Joseph J. Eron and Michael W. Fried and R. Kevin Robertson},
url = {http://ict.usc.edu/pubs/Neurocognitive%20functioning%20and%20HAART%20in%20HIV%20and%20hepatitis%20C%20virus%20co-infection.pdf},
year = {2006},
date = {2006-05-01},
journal = {AIDS},
volume = {20},
pages = {1591–1595},
abstract = {Objectives: This study examined the effects of HAART on neurocognitive functioning in persons with hepatitis C virus (HCV) and HIV co-infection. Design: A prospective study examining neurocognitive performance before and after HAART initiation. Method: Participant groups included a mono-infected group (45 HIV/HCV-participants) and a co-infected group (20 HIV/HCV participants). A neuropsychological battery (attention/concentration, psychomotor speed, executive functioning, verbal memory, visual memory, ï¬ne motor, and gross motor functioning) was used to evaluate all participants. After 6 months of HAART, 31 HIV mono-infected and 13 HCV/ HIV co-infected participants were reevaluated. Results: Neurocognitive functioning by domain revealed signiï¬cantly worse performance in the co-infected group when compared to the monoinfected group on domains of visual memory and ï¬ne motor functioning. Assessment of neurocognitive functioning after antiretroviral therapy revealed that the co-infected group was no longer performing worse than the monoinfected group. Conclusions: The ï¬ndings of the current study suggest that persons with HCV/HIV co-infection may have greater neurocognitive declines than persons with HIV infection alone. HCV/HIV co-infection may accelerate the progression of HIV related neurocognitive decline.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Objectives: This study examined the effects of HAART on neurocognitive functioning in persons with hepatitis C virus (HCV) and HIV co-infection. Design: A prospective study examining neurocognitive performance before and after HAART initiation. Method: Participant groups included a mono-infected group (45 HIV/HCV-participants) and a co-infected group (20 HIV/HCV participants). A neuropsychological battery (attention/concentration, psychomotor speed, executive functioning, verbal memory, visual memory, ï¬ne motor, and gross motor functioning) was used to evaluate all participants. After 6 months of HAART, 31 HIV mono-infected and 13 HCV/ HIV co-infected participants were reevaluated. Results: Neurocognitive functioning by domain revealed signiï¬cantly worse performance in the co-infected group when compared to the monoinfected group on domains of visual memory and ï¬ne motor functioning. Assessment of neurocognitive functioning after antiretroviral therapy revealed that the co-infected group was no longer performing worse than the monoinfected group. Conclusions: The ï¬ndings of the current study suggest that persons with HCV/HIV co-infection may have greater neurocognitive declines than persons with HIV infection alone. HCV/HIV co-infection may accelerate the progression of HIV related neurocognitive decline.
Rizzo, Albert; Pair, Jarrell; Graap, Ken; Manson, Brian; McNerney, Peter J.; Wiederhold, Brenda K.; Wiederhold, Mark; Spira, James
A Virtual Reality Exposure Therapy Application for Iraq War Military Personnel with Post Traumatic Stress Disorder: From Training to Toy to Treatment Proceedings Article
In: NATO Advanced Research Workshop on Novel Approached to the Diagnosis and Treatment of Posttraumatic Stress Disorder, 2006.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@inproceedings{rizzo_virtual_2006,
title = {A Virtual Reality Exposure Therapy Application for Iraq War Military Personnel with Post Traumatic Stress Disorder: From Training to Toy to Treatment},
author = {Albert Rizzo and Jarrell Pair and Ken Graap and Brian Manson and Peter J. McNerney and Brenda K. Wiederhold and Mark Wiederhold and James Spira},
url = {http://ict.usc.edu/pubs/A%20Virtual%20Reality%20Exposure%20Therapy%20Application%20for%20Iraq%20War%20Military%20Personnel%20with%20Post%20Traumatic%20Stress%20Disorder-%20From%20Training%20to%20Toy%20to%20Treatment.pdf},
year = {2006},
date = {2006-03-01},
booktitle = {NATO Advanced Research Workshop on Novel Approached to the Diagnosis and Treatment of Posttraumatic Stress Disorder},
abstract = {Post Traumatic Stress Disorder is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to specify the rationale, design and development of a Virtual Iraq PTSD VR application that has been created from the virtual assets that were initially developed for a combat tactical training simulation, which then served as the inspiration for the X-Box game entitled Full Spectrum Warrior.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to specify the rationale, design and development of a Virtual Iraq PTSD VR application that has been created from the virtual assets that were initially developed for a combat tactical training simulation, which then served as the inspiration for the X-Box game entitled Full Spectrum Warrior.
Pair, Jarrell; Allen, Brian; Dautricourt, Matthieu; Treskunov, Anton; Liewer, Matt; Graap, Ken; Reger, Greg; Rizzo, Albert
A Virtual Reality Exposure Therapy Application for Iraq War Post Traumatic Stress Disorder Proceedings Article
In: Proceedings of the IEEE VR 2006 Conference, pp. 64–71, Alexandria, VA, 2006.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@inproceedings{pair_virtual_2006,
title = {A Virtual Reality Exposure Therapy Application for Iraq War Post Traumatic Stress Disorder},
author = {Jarrell Pair and Brian Allen and Matthieu Dautricourt and Anton Treskunov and Matt Liewer and Ken Graap and Greg Reger and Albert Rizzo},
url = {http://ict.usc.edu/pubs/A%20Virtual%20Reality%20Exposure%20Therapy%20Application%20for%20Iraq%20War%20Post%20Traumatic%20Stress%20Disorder.pdf},
year = {2006},
date = {2006-03-01},
booktitle = {Proceedings of the IEEE VR 2006 Conference},
pages = {64–71},
address = {Alexandria, VA},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-Centered tests with the application are currently underway at the Naval Medical Center–San Diego and within an Army Combat Stress Control Team in Iraq with clinical trials scheduled to commence in February 2006.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-Centered tests with the application are currently underway at the Naval Medical Center–San Diego and within an Army Combat Stress Control Team in Iraq with clinical trials scheduled to commence in February 2006.
Buxbaum, Laurel J.; Palermo, Maryann; Mastrogiovanni, Dina; Read, Mary Schmidt; Rosenberg-Pitonyak, Ellen; Rizzo, Albert; Coslett, H. Branch
Assessment of Spatial Neglect with a Virtual Wheelchair Navigation Task Proceedings Article
In: 5th Annual International Workshop on Virtual Rehabilitation, New York, NY, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@inproceedings{buxbaum_assessment_2006,
title = {Assessment of Spatial Neglect with a Virtual Wheelchair Navigation Task},
author = {Laurel J. Buxbaum and Maryann Palermo and Dina Mastrogiovanni and Mary Schmidt Read and Ellen Rosenberg-Pitonyak and Albert Rizzo and H. Branch Coslett},
url = {http://ict.usc.edu/pubs/Assessment%20of%20Spatial%20Neglect%20with%20a%20Virtual%20Wheelchair%20Navigation%20Task.pdf},
year = {2006},
date = {2006-01-01},
booktitle = {5th Annual International Workshop on Virtual Rehabilitation},
address = {New York, NY},
abstract = {We report data from 9 participants with right hemisphere stroke on a new virtual reality (VR) wheelchair navigation test designed to assess lateralized spatial attention and neglect. The test consists of a virtual winding path along which participants must navigate (or be navigated by an experimenter) as they name objects encountered along the way. There are 4 VR task conditions, obtained by crossing the factors array complexity (Simple, Complex) and Driver (Participant, Experimenter). Participants performed the VR task, a real-life wheelchair navigation task, and a battery of tests assessing arousal, visual attention under secondary task demands, and neglect. The VR test showed sensitivity to both array complexity and driver, with best performance occurring in the Experimenter Navigated, Simple Array condition. The VR test also showed high correlations with the wheelchair navigation test, and these correlations were in many instances higher than those between traditional clinical neglect tests and the wheelchair navigation task. Moreover, the VR test detected lateralized attention deficits in participants whose performance was within the normal range on other neglect tests. We conclude that the VR task is sensitive to factors likely to affect the severity of neglect in the daily environment, and shows promise as an efficient, easily administered measure of real-life wheelchair navigation.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {inproceedings}
}
We report data from 9 participants with right hemisphere stroke on a new virtual reality (VR) wheelchair navigation test designed to assess lateralized spatial attention and neglect. The test consists of a virtual winding path along which participants must navigate (or be navigated by an experimenter) as they name objects encountered along the way. There are 4 VR task conditions, obtained by crossing the factors array complexity (Simple, Complex) and Driver (Participant, Experimenter). Participants performed the VR task, a real-life wheelchair navigation task, and a battery of tests assessing arousal, visual attention under secondary task demands, and neglect. The VR test showed sensitivity to both array complexity and driver, with best performance occurring in the Experimenter Navigated, Simple Array condition. The VR test also showed high correlations with the wheelchair navigation test, and these correlations were in many instances higher than those between traditional clinical neglect tests and the wheelchair navigation task. Moreover, the VR test detected lateralized attention deficits in participants whose performance was within the normal range on other neglect tests. We conclude that the VR task is sensitive to factors likely to affect the severity of neglect in the daily environment, and shows promise as an efficient, easily administered measure of real-life wheelchair navigation.
Nelson, Nathaniel W.; Parsons, Thomas D.; Grote, Christopher L.; Smith, Clifford A.; II, James R. Sisung
The MMPI-2 Fake Bad Scale: Concordance and Specificity of True and Estimated Scores Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 28, pp. 1–12, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{nelson_mmpi-2_2006,
title = {The MMPI-2 Fake Bad Scale: Concordance and Specificity of True and Estimated Scores},
author = {Nathaniel W. Nelson and Thomas D. Parsons and Christopher L. Grote and Clifford A. Smith and James R. Sisung II},
url = {http://ict.usc.edu/pubs/The%20MMPI-2%20Fake%20Bad%20Scale-%20Concordance%20and%20Specificity%20of%20True%20and%20Estimated%20Scores.pdf},
doi = {10.1080/13803390490919272},
year = {2006},
date = {2006-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {28},
pages = {1–12},
series = {1380-339},
abstract = {A number of recent studies have supported the use of the MMPI-2 Fake Bad Scale (FBS) as a measure of negative response bias, the scale at times demonstrating greater sensitivity to negative response bias than other MMPI-2 validity scales. However, clinicians may not always have access to True FBS (T-FBS) scores, such as when True-False answer sheets are unavailable or published research studies do not report FBS raw scores. Under these conditions, Larrabee (2003a) suggests a linear regression formula that provides estimated FBS (E-FBS) scores derived from weighted validity and clinical T-Scores. The present study intended to validate this regression formula of MMPI-2 E-FBS scores and demonstrate its specificity in a sample of non-litigating, clinically referred, medically intractable epilepsy patients. We predicted that the E-FBS scores would correlate highly (textbackslashtextbackslashtextbackslashtextbackslashtextgreater.70) with the T-FBS scores, that the E-FBS would show comparable correlations with MMPI-2 validity and clinical scales relative to the T-FBS, and that the E-FBS would show an adequate ability to match T-FBS scores using a variety of previously suggested T-FBS raw score cutoffs. Overall, E-FBS scores correlated very highly with T-FBS scores (r = .78, p textbackslashtextbackslashtextbackslashtextbackslashtextless .0001), though correlations were especially high for women (r = .85, p textbackslashtextbackslashtextbackslashtextbackslashtextless .0001) compared to men (r = .62, p textbackslashtextbackslashtextbackslashtextbackslashtextless .001). Thirty-one of 32 (96.9%) comparisons made between E-FBS/T-FBS correlates with other MMPI-2 scales were nonsignificant. When matching to T-FBS "high" and "low" scores, the E-FBS scores demonstrated the highest hit rate (92.5%) through use of Lees-Haley's (1992) revised cutoffs for men and women. These same cutoffs resulted in excellent overall specificity for both the T-FBS scores (92.5%) and E-FBS scores (90.6%). The authors conclude that the E-FBS represents an adequate estimate of T-FBS scores in the current epilepsy sample. Use of E-FBS scores may be especially useful when clinicians conduct the MMPI-2 short form, which does not include all of the 43 FBS items but does include enough items to compute each of the validity and clinical T-Scores. Future studies should examine E-FBS sensitivity in compensation-seekers with incomplete effort.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
A number of recent studies have supported the use of the MMPI-2 Fake Bad Scale (FBS) as a measure of negative response bias, the scale at times demonstrating greater sensitivity to negative response bias than other MMPI-2 validity scales. However, clinicians may not always have access to True FBS (T-FBS) scores, such as when True-False answer sheets are unavailable or published research studies do not report FBS raw scores. Under these conditions, Larrabee (2003a) suggests a linear regression formula that provides estimated FBS (E-FBS) scores derived from weighted validity and clinical T-Scores. The present study intended to validate this regression formula of MMPI-2 E-FBS scores and demonstrate its specificity in a sample of non-litigating, clinically referred, medically intractable epilepsy patients. We predicted that the E-FBS scores would correlate highly (textbackslashtextbackslashtextbackslashtextbackslashtextgreater.70) with the T-FBS scores, that the E-FBS would show comparable correlations with MMPI-2 validity and clinical scales relative to the T-FBS, and that the E-FBS would show an adequate ability to match T-FBS scores using a variety of previously suggested T-FBS raw score cutoffs. Overall, E-FBS scores correlated very highly with T-FBS scores (r = .78, p textbackslashtextbackslashtextbackslashtextbackslashtextless .0001), though correlations were especially high for women (r = .85, p textbackslashtextbackslashtextbackslashtextbackslashtextless .0001) compared to men (r = .62, p textbackslashtextbackslashtextbackslashtextbackslashtextless .001). Thirty-one of 32 (96.9%) comparisons made between E-FBS/T-FBS correlates with other MMPI-2 scales were nonsignificant. When matching to T-FBS "high" and "low" scores, the E-FBS scores demonstrated the highest hit rate (92.5%) through use of Lees-Haley's (1992) revised cutoffs for men and women. These same cutoffs resulted in excellent overall specificity for both the T-FBS scores (92.5%) and E-FBS scores (90.6%). The authors conclude that the E-FBS represents an adequate estimate of T-FBS scores in the current epilepsy sample. Use of E-FBS scores may be especially useful when clinicians conduct the MMPI-2 short form, which does not include all of the 43 FBS items but does include enough items to compute each of the validity and clinical T-Scores. Future studies should examine E-FBS sensitivity in compensation-seekers with incomplete effort.
Parsons, Thomas D.; Kratz, K. M.; Thompson, E.; Stanczyk, F. Z.; Buckwalter, John Galen
DHEA Supplementation and Cognition in Postmenopausal Women Journal Article
In: International Journal of Neuroscience, vol. 16, pp. 141–155, 2006, ISSN: 0020-7454.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_dhea_2006,
title = {DHEA Supplementation and Cognition in Postmenopausal Women},
author = {Thomas D. Parsons and K. M. Kratz and E. Thompson and F. Z. Stanczyk and John Galen Buckwalter},
url = {http://ict.usc.edu/pubs/DHEA%20Supplementation%20and%20Cognition%20in%20Postmenopausal%20Women.pdf},
doi = {10.1080/00207450500341506},
issn = {0020-7454},
year = {2006},
date = {2006-01-01},
journal = {International Journal of Neuroscience},
volume = {16},
pages = {141–155},
abstract = {Previous work has suggested that DHEA supplementation may have adverse cognitive effects in elderly women. This article analyzed 24-h measurements of DHEA, DHEAS, and cortisol to determine if cognitive decrease with treatment is mediated by DHEA’s impact on endogenous cortisol. It was found that DHEA administration increased cortisol at several hours during the day. In the treatment group, cortisol was positively associated with cognition at study completion. An increase in negative associations between DHEA(S) levels and cognition was found at completion. Increased cortisol does not explain the cognitive deficits associated with DHEA, suggesting a direct negative effect of exogenous DHEA on cognition.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Previous work has suggested that DHEA supplementation may have adverse cognitive effects in elderly women. This article analyzed 24-h measurements of DHEA, DHEAS, and cortisol to determine if cognitive decrease with treatment is mediated by DHEA’s impact on endogenous cortisol. It was found that DHEA administration increased cortisol at several hours during the day. In the treatment group, cortisol was positively associated with cognition at study completion. An increase in negative associations between DHEA(S) levels and cognition was found at completion. Increased cortisol does not explain the cognitive deficits associated with DHEA, suggesting a direct negative effect of exogenous DHEA on cognition.
Feintuch, Uri; Liat, Raz; Hwang, Jane; Josman, Naomi; Katz, Noomi; Kizony, Rachel; Rand, Debbie; Rizzo, Albert; Shahar, Meir; Yongseok, Jang; Weiss, Patrice L. (Tamar)
Integrating haptic-tactile feedback into a video capture based VE for rehabilitation Journal Article
In: CyberPsychology and Behavior, vol. 9, no. 2, pp. 129–132, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{feintuch_integrating_2006,
title = {Integrating haptic-tactile feedback into a video capture based VE for rehabilitation},
author = {Uri Feintuch and Raz Liat and Jane Hwang and Naomi Josman and Noomi Katz and Rachel Kizony and Debbie Rand and Albert Rizzo and Meir Shahar and Jang Yongseok and Patrice L. (Tamar) Weiss},
url = {http://ict.usc.edu/pubs/Integrating%20Haptic-Tactile%20Feedback%20into%20a%20Video-Capture%E2%80%93Based%20Virtual%20Environment%20for%20Rehabilitation.pdf},
year = {2006},
date = {2006-01-01},
journal = {CyberPsychology and Behavior},
volume = {9},
number = {2},
pages = {129–132},
abstract = {Video-capture virtual reality (VR) systems are gaining popularity as intervention tools. Todate, these platforms offer visual and audio feedback but do not provide haptic feedback. Wecontend that adding haptic feedback may enhance the quality of intervention for various theoretical and empirical reasons. This study aims to integrate haptic-tactile feedback into avideo capture system (GX VR), which is currently applied for rehabilitation. The proposedmulti-modal system can deliver audio-visual as well as vibrotactile feedback. The latter isprovided via small vibratory discs attached to the patient's limbs. This paper describes thesystem, the guidelines of its design, and the ongoing usability study.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Video-capture virtual reality (VR) systems are gaining popularity as intervention tools. Todate, these platforms offer visual and audio feedback but do not provide haptic feedback. Wecontend that adding haptic feedback may enhance the quality of intervention for various theoretical and empirical reasons. This study aims to integrate haptic-tactile feedback into avideo capture system (GX VR), which is currently applied for rehabilitation. The proposedmulti-modal system can deliver audio-visual as well as vibrotactile feedback. The latter isprovided via small vibratory discs attached to the patient's limbs. This paper describes thesystem, the guidelines of its design, and the ongoing usability study.
Robertson, R. Kevin; Parsons, Thomas D.; Horst, Charles; Hall, Colin D.
Thoughts of death and suicidal ideation in nonpsychiatric human immunodeficiency virus seropositive individuals Journal Article
In: Death Studies, vol. 30, pp. 455–469, 2006, ISSN: 0748-1187.
Abstract | Links | BibTeX | Tags: MedVR
@article{robertson_thoughts_2006,
title = {Thoughts of death and suicidal ideation in nonpsychiatric human immunodeficiency virus seropositive individuals},
author = {R. Kevin Robertson and Thomas D. Parsons and Charles Horst and Colin D. Hall},
url = {http://ict.usc.edu/pubs/THOUGHTS%20OF%20DEATH%20AND%20SUICIDAL%20IDEATION%20IN%20NONPSYCHIATRIC%20HUMAN%20IMMUNODEFICIENCY%20VIRUS%20SEROPOSITIVE%20INDIVIDUALS.pdf},
doi = {10.1080/07481180600614435},
issn = {0748-1187},
year = {2006},
date = {2006-01-01},
journal = {Death Studies},
volume = {30},
pages = {455–469},
abstract = {The present study examines the prevalence of death thoughts and suicidality in HIV infection. Subjects (n = 246) were examined for psychiatric morbidity and suicidality. Compared to high risk HIV seronegatives, HIV seropositives (HIV•) had significantly increased frequency and severity of both suicidal ideation and death thoughts. Two-thirds of seropositives had suicidal ideation at some point; half of the seropositives reported suicide plans and one quarter suicide attempts; and third of seropositives reported current suicidal ideation. Suicidal ideation did not increase with advancing disease. The high prevalence of suicidal ideation suggests inclusion of its assessment in HIV treatment regardless of stage.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The present study examines the prevalence of death thoughts and suicidality in HIV infection. Subjects (n = 246) were examined for psychiatric morbidity and suicidality. Compared to high risk HIV seronegatives, HIV seropositives (HIV•) had significantly increased frequency and severity of both suicidal ideation and death thoughts. Two-thirds of seropositives had suicidal ideation at some point; half of the seropositives reported suicide plans and one quarter suicide attempts; and third of seropositives reported current suicidal ideation. Suicidal ideation did not increase with advancing disease. The high prevalence of suicidal ideation suggests inclusion of its assessment in HIV treatment regardless of stage.
Gold, Jeffrey I.; Kim, Seok Hyeon; Kant, Alexis J.; Joseph, Michael H.; Rizzo, Albert
Effectiveness of Virtual Reality for Pediatric Pain Distraction during IV Placement Journal Article
In: CyberPsychology and Behavior, vol. 9, no. 2, pp. 207–212, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{gold_effectiveness_2006,
title = {Effectiveness of Virtual Reality for Pediatric Pain Distraction during IV Placement},
author = {Jeffrey I. Gold and Seok Hyeon Kim and Alexis J. Kant and Michael H. Joseph and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Effectiveness%20of%20Virtual%20Reality%20for%20Pediatric%20Pain%20Distraction%20during%20IV%20Placement.pdf},
year = {2006},
date = {2006-01-01},
journal = {CyberPsychology and Behavior},
volume = {9},
number = {2},
pages = {207–212},
abstract = {The objective of this study was to test the efficacy and suitability of virtual reality (VR) as apain distraction for pediatric intravenous (IV) placement. Twenty children (12 boys, 8 girls) requiring IV placement for a magnetic resonance imaging/computed tomography (MRI/CT) scan were randomly assigned to two conditions: (1) VR distraction using Street Luge(5DT), presented via a head-mounted display, or (2) standard of care (topical anesthetic) with no distraction. Children, their parents, and nurses completed self-report questionnaires that assessed numerous health-related outcomes. Responses from the Faces Pain Scale–Revisedindicated a fourfold increase in affective pain within the control condition; by contrast, nosignificant differences were detected within the VR condition. Significant associations between multiple measures of anticipatory anxiety, affective pain, IV pain intensity, and measures of past procedural pain provided support for the complex interplay of a multimodalassessment of pain perception. There was also a sufficient amount of evidence supportingthe efficacy of Street Luge as a pediatric pain distraction tool during IV placement: an adequate level of presence, no simulator sickness, and significantly more child-, parent-, and nurse-reported satisfaction with pain management. VR pain distraction was positively endorsed by all reporters and is a promising tool for decreasing pain, and anxiety in childrenundergoing acute medical interventions. However, further research with larger sample sizesand other routine medical procedures is warranted.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The objective of this study was to test the efficacy and suitability of virtual reality (VR) as apain distraction for pediatric intravenous (IV) placement. Twenty children (12 boys, 8 girls) requiring IV placement for a magnetic resonance imaging/computed tomography (MRI/CT) scan were randomly assigned to two conditions: (1) VR distraction using Street Luge(5DT), presented via a head-mounted display, or (2) standard of care (topical anesthetic) with no distraction. Children, their parents, and nurses completed self-report questionnaires that assessed numerous health-related outcomes. Responses from the Faces Pain Scale–Revisedindicated a fourfold increase in affective pain within the control condition; by contrast, nosignificant differences were detected within the VR condition. Significant associations between multiple measures of anticipatory anxiety, affective pain, IV pain intensity, and measures of past procedural pain provided support for the complex interplay of a multimodalassessment of pain perception. There was also a sufficient amount of evidence supportingthe efficacy of Street Luge as a pediatric pain distraction tool during IV placement: an adequate level of presence, no simulator sickness, and significantly more child-, parent-, and nurse-reported satisfaction with pain management. VR pain distraction was positively endorsed by all reporters and is a promising tool for decreasing pain, and anxiety in childrenundergoing acute medical interventions. However, further research with larger sample sizesand other routine medical procedures is warranted.
Braaten, Alyssa J.; Parsons, Thomas D.; McCue, Robert; Sellers, Alfred; Burns, William J.
In: International Journal of Neuroscience, vol. 116, pp. 1271–1293, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{braaten_neurocognitive_2006,
title = {Neurocognitive Differential Diagnosis of Dementing Diseases: Alzheimers Demntia, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder},
author = {Alyssa J. Braaten and Thomas D. Parsons and Robert McCue and Alfred Sellers and William J. Burns},
url = {http://ict.usc.edu/pubs/NEUROCOGNITIVE%20DIFFERENTIAL%20DIAGNOSIS%20OF%20DEMENTING%20DISEASES-%20ALZHEIMER%E2%80%99S%20DEMENTIA,%20VASCULAR%20DEMENTIA,%20FRONTOTEMPORAL%20DEMENTIA,%20AND%20MAJOR%20DEPRESSIVE%20DISORDER.pdf},
year = {2006},
date = {2006-01-01},
journal = {International Journal of Neuroscience},
volume = {116},
pages = {1271–1293},
abstract = {Similarities in presentation of Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder, pose differential diagnosis challenges. The current study identiï¬es speciï¬c neuropsychological patterns of scores for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. Neuropsychological domains directly assessed in the study included: immediate memory, delayed memory, confrontational naming, verbal fluency, attention, concentration, and executive functioning. The results reveal speciï¬c neuropsychological comparative proï¬les for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. The identiï¬cation of these proï¬les will assist in the differential diagnosis of these disorders and aid in patient treatment.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Similarities in presentation of Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder, pose differential diagnosis challenges. The current study identiï¬es speciï¬c neuropsychological patterns of scores for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. Neuropsychological domains directly assessed in the study included: immediate memory, delayed memory, confrontational naming, verbal fluency, attention, concentration, and executive functioning. The results reveal speciï¬c neuropsychological comparative proï¬les for Dementia of Alzheimer's Type, Vascular Dementia, Frontotemporal Dementia, and Major Depressive Disorder. The identiï¬cation of these proï¬les will assist in the differential diagnosis of these disorders and aid in patient treatment.
Rizzo, Albert; Graap, Ken; Pair, Jarrell; Reger,; Treskunov, Anton; Parsons, Thomas D.
User-centered design driven development of a virtual reality therapy application for Iraq war combat-related post traumatic stress disorder Proceedings Article
In: Proceedings of the 2006 International Conference on Disability, Virtual Reality and Associated Technology, Esbjerg, Denmark, 2006.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@inproceedings{rizzo_user-centered_2006,
title = {User-centered design driven development of a virtual reality therapy application for Iraq war combat-related post traumatic stress disorder},
author = {Albert Rizzo and Ken Graap and Jarrell Pair and Reger and Anton Treskunov and Thomas D. Parsons},
url = {http://ict.usc.edu/pubs/User-centered%20design%20driven%20development%20of%20a%20virtual%20reality%20therapy%20application%20for%20Iraq%20war%20combat-related%20post%20traumatic%20stress%20disorder.pdf},
year = {2006},
date = {2006-01-01},
booktitle = {Proceedings of the 2006 International Conference on Disability, Virtual Reality and Associated Technology},
address = {Esbjerg, Denmark},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system in Iraq tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center. Other sites are preparing to use the application for a variety of PTSD and VR research purposes.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system in Iraq tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center. Other sites are preparing to use the application for a variety of PTSD and VR research purposes.
Parsons, Thomas D.; Braaten, Alyssa J.; Hall, Colin D.; Robertson, R. Kevin
Better quality of life with neuropsychological improvement on HAART Journal Article
In: Health and Quality of Life Outcomes, vol. 4, no. 11, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_better_2006,
title = {Better quality of life with neuropsychological improvement on HAART},
author = {Thomas D. Parsons and Alyssa J. Braaten and Colin D. Hall and R. Kevin Robertson},
url = {http://ict.usc.edu/pubs/Better%20quality%20of%20life%20with%20neuropsychological%20improvement%20on%20HAART.pdf},
year = {2006},
date = {2006-01-01},
journal = {Health and Quality of Life Outcomes},
volume = {4},
number = {11},
abstract = {Background: Successful highly active antiretroviral therapy (HAART) regimens have resulted in substantial improvements in the systemic health of HIV infected persons and increased survival times. Despite increased systemic health, the prevalence of minor HIV-associated cognitive impairment appears to be rising with increased longevity, and it remains to be seen what functional outcomes will result from these improvements. Cognitive impairment can dramatically impact functional ability and day-to-day productivity. We assessed the relationship of quality of life (QOL) and neuropsychological functioning with successful HAART treatment. Methods: In a prospective longitudinal study, subjects were evaluated before instituting HAART (naïve) or before changing HAART regimens because current therapy failed to maintain suppression of plasma viral load (treatment failure). Subjects underwent detailed neuropsychological and neurological examinations, as well as psychological evaluation sensitive to possible confounds. Re-evaluation was performed six months after institution of the new HAART regimen and/or if plasma viral load indicated treatment failure. At each evaluation, subjects underwent ultrasensitive HIV RNA quantitative evaluation in both plasma and cerebrospinal fluid. Results: HAART successes performed better than failures on measures exploring speed of mental processing (p textbackslashtextbackslashtextbackslashtextbackslashtextless .02). HAART failure was significantly associated with increased self-reports of physical health complaints (p textbackslashtextbackslashtextbackslashtextbackslashtextless .01) and substance abuse (p textbackslashtextbackslashtextbackslashtextbackslashtextless .01). An interesting trend emerged, in which HAART failures endorsed greater levels of psychological and cognitive complaints (p = 06). Analysis between neuropsychological measures and QOL scores revealed significant. correlation between QOL Total and processing speed (p textbackslashtextbackslashtextbackslashtextbackslashtextless .05), as well as flexibility (p textbackslashtextbackslashtextbackslashtextbackslashtextless .05). Conclusion: Our study investigated the relationship between HIV-associated neurocognitive impairment and quality of life. HAART failures experienced slower psychomotor processing, and had increased self-reports of physical health complaints and substance abuse. Contrariwise, HAART successes experienced improved mental processing, demonstrating the impact of successful treatment on functioning. With increasing life expectancy for those who are HIV seropositive, it is important to measure cognitive functioning in relation to the actual QOL these individuals report. The study results have implications for the optimal management of HIV-infected persons. Specific support or intervention may be beneficial for those who have failed HAART in order to decrease substance abuse and increase overall physical health.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
Background: Successful highly active antiretroviral therapy (HAART) regimens have resulted in substantial improvements in the systemic health of HIV infected persons and increased survival times. Despite increased systemic health, the prevalence of minor HIV-associated cognitive impairment appears to be rising with increased longevity, and it remains to be seen what functional outcomes will result from these improvements. Cognitive impairment can dramatically impact functional ability and day-to-day productivity. We assessed the relationship of quality of life (QOL) and neuropsychological functioning with successful HAART treatment. Methods: In a prospective longitudinal study, subjects were evaluated before instituting HAART (naïve) or before changing HAART regimens because current therapy failed to maintain suppression of plasma viral load (treatment failure). Subjects underwent detailed neuropsychological and neurological examinations, as well as psychological evaluation sensitive to possible confounds. Re-evaluation was performed six months after institution of the new HAART regimen and/or if plasma viral load indicated treatment failure. At each evaluation, subjects underwent ultrasensitive HIV RNA quantitative evaluation in both plasma and cerebrospinal fluid. Results: HAART successes performed better than failures on measures exploring speed of mental processing (p textbackslashtextbackslashtextbackslashtextbackslashtextless .02). HAART failure was significantly associated with increased self-reports of physical health complaints (p textbackslashtextbackslashtextbackslashtextbackslashtextless .01) and substance abuse (p textbackslashtextbackslashtextbackslashtextbackslashtextless .01). An interesting trend emerged, in which HAART failures endorsed greater levels of psychological and cognitive complaints (p = 06). Analysis between neuropsychological measures and QOL scores revealed significant. correlation between QOL Total and processing speed (p textbackslashtextbackslashtextbackslashtextbackslashtextless .05), as well as flexibility (p textbackslashtextbackslashtextbackslashtextbackslashtextless .05). Conclusion: Our study investigated the relationship between HIV-associated neurocognitive impairment and quality of life. HAART failures experienced slower psychomotor processing, and had increased self-reports of physical health complaints and substance abuse. Contrariwise, HAART successes experienced improved mental processing, demonstrating the impact of successful treatment on functioning. With increasing life expectancy for those who are HIV seropositive, it is important to measure cognitive functioning in relation to the actual QOL these individuals report. The study results have implications for the optimal management of HIV-infected persons. Specific support or intervention may be beneficial for those who have failed HAART in order to decrease substance abuse and increase overall physical health.
Miller, Karen J.; Parsons, Thomas D.; Whybrow, Peter C.; Herle, Katja; Rasgon, Natalie; Herle, Andre; Martinez, Dorothy; Silverman, Dan H.; Bauer, Michael
Memory Improvement with Treatment of Hypothyroidism Journal Article
In: International Journal of Neuroscience, vol. 16, no. 8, pp. 895–906, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{miller_memory_2006,
title = {Memory Improvement with Treatment of Hypothyroidism},
author = {Karen J. Miller and Thomas D. Parsons and Peter C. Whybrow and Katja Herle and Natalie Rasgon and Andre Herle and Dorothy Martinez and Dan H. Silverman and Michael Bauer},
url = {http://ict.usc.edu/pubs/Memory%20Improvement%20with%20Treatment%20of%20Hypothyroidism.pdf},
year = {2006},
date = {2006-01-01},
journal = {International Journal of Neuroscience},
volume = {16},
number = {8},
pages = {895–906},
abstract = {The consequences of inadequate thyroid hormone availability to the brain and treatment effects of levothyroxine function are still poorly understood. This study prospectively assessed the effects of thyroid replacement therapy on cognitive function in patients suffering from biochemical evidenced, untreated hypothyroidism. Significant effects between the untreated hypothyroid group and control group were limited to verbal memory retrieval. When assessing the effects of 3-month treatment, results revealed that the treated hypothyroid group had significant increased verbal memory retrieval. Results suggest that specific memory retrieval deficits associated with hypothyroidism can resolve after replacement therapy with levothyroxine.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The consequences of inadequate thyroid hormone availability to the brain and treatment effects of levothyroxine function are still poorly understood. This study prospectively assessed the effects of thyroid replacement therapy on cognitive function in patients suffering from biochemical evidenced, untreated hypothyroidism. Significant effects between the untreated hypothyroid group and control group were limited to verbal memory retrieval. When assessing the effects of 3-month treatment, results revealed that the treated hypothyroid group had significant increased verbal memory retrieval. Results suggest that specific memory retrieval deficits associated with hypothyroidism can resolve after replacement therapy with levothyroxine.
Tröster, Alexander I.; Parsons, Thomas D.
Sodium Amytal Testing and Language Journal Article
In: Encyclopedia of Language and Linguistics, vol. 11, pp. 500–503, 2006.
Abstract | Links | BibTeX | Tags: MedVR
@article{troster_sodium_2006,
title = {Sodium Amytal Testing and Language},
author = {Alexander I. Tröster and Thomas D. Parsons},
url = {http://ict.usc.edu/pubs/Sodium%20Amytal%20Testing%20and%20Language.pdf},
year = {2006},
date = {2006-01-01},
journal = {Encyclopedia of Language and Linguistics},
volume = {11},
pages = {500–503},
abstract = {The intracarotid amobarbital test (IAT) was first described by Juhn Wada and thus is often referred to as the 'Wada test.' Wada originally developed this technique to study the interhemispheric spread of epileptiform discharges in patients undergoing unilateral electroconvulsive therapy. Based on his observation that an expressive aphasia resulted when the language dominant hemisphere was injected with amobarbital, he reasoned that this technique might be useful in determining hemispheric language dominance in neurosurgical candidates (and thus minimize speech and language dysfunction in patients undergoing dominant hemisphere surgery).},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The intracarotid amobarbital test (IAT) was first described by Juhn Wada and thus is often referred to as the 'Wada test.' Wada originally developed this technique to study the interhemispheric spread of epileptiform discharges in patients undergoing unilateral electroconvulsive therapy. Based on his observation that an expressive aphasia resulted when the language dominant hemisphere was injected with amobarbital, he reasoned that this technique might be useful in determining hemispheric language dominance in neurosurgical candidates (and thus minimize speech and language dysfunction in patients undergoing dominant hemisphere surgery).
Woods, Steven Paul; Rippeth, Julie D.; Conover, Emily; Carey, Catherine L.; Parsons, Thomas D.; Tröster, Alexander I.
Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease Journal Article
In: The Clinical Neuropsychologist, vol. 20, pp. 27–38, 2006, ISSN: 1385-4046.
Abstract | Links | BibTeX | Tags: MedVR
@article{woods_statistical_2006,
title = {Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease},
author = {Steven Paul Woods and Julie D. Rippeth and Emily Conover and Catherine L. Carey and Thomas D. Parsons and Alexander I. Tröster},
url = {http://ict.usc.edu/pubs/STATISTICAL%20POWER%20OF%20STUDIES%20EXAMINING%20THE%20COGNITIVE%20EFFECTS%20OF%20SUBTHALAMIC%20NUCLEUS%20DEEP%20BRAIN%20STIMULATION%20IN%20PARKINSON%E2%80%99S%20DISEASE.pdf},
doi = {10.1080/13854040500203290},
issn = {1385-4046},
year = {2006},
date = {2006-01-01},
journal = {The Clinical Neuropsychologist},
volume = {20},
pages = {27–38},
abstract = {It has been argued that neuropsychological studies generally possess adequate statistical power to detect large effect sizes. However, low statistical power is problematic in neuropsychological research involving clinical populations and novel interventions for which available sample sizes are often limited. One notable example of this problem is evident in the literature regarding the cognitive sequelae of deep brain stimulation (DBS) of the subthalamic nucleus (STN) in persons with Parkinson's disease (PD). In the current review, a post hoc estimate of the statistical power of 30 studies examining cognitive effects of STN DBS in PD revealed adequate power to detect substantial cognitive declines (i.e., very large effect sizes), but surprisingly low estimated power to detect cognitive changes associated with conventionally small, medium, and large effect sizes. Such wide spread Type II error risk in the STN DBS cognitive outcomes literature may affect the clinical decision-making process as concerns the possible risk of postsurgical cognitive morbidity, as well as conceptual inferences to be drawn regarding the role of the STN in higher-level cognitive functions. Statistical and methodological recommendations (e.g., meta-analysis) are offered to enhance the power of current and future studies examining the neuropsychological sequelae of STN DBS in PD.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
It has been argued that neuropsychological studies generally possess adequate statistical power to detect large effect sizes. However, low statistical power is problematic in neuropsychological research involving clinical populations and novel interventions for which available sample sizes are often limited. One notable example of this problem is evident in the literature regarding the cognitive sequelae of deep brain stimulation (DBS) of the subthalamic nucleus (STN) in persons with Parkinson's disease (PD). In the current review, a post hoc estimate of the statistical power of 30 studies examining cognitive effects of STN DBS in PD revealed adequate power to detect substantial cognitive declines (i.e., very large effect sizes), but surprisingly low estimated power to detect cognitive changes associated with conventionally small, medium, and large effect sizes. Such wide spread Type II error risk in the STN DBS cognitive outcomes literature may affect the clinical decision-making process as concerns the possible risk of postsurgical cognitive morbidity, as well as conceptual inferences to be drawn regarding the role of the STN in higher-level cognitive functions. Statistical and methodological recommendations (e.g., meta-analysis) are offered to enhance the power of current and future studies examining the neuropsychological sequelae of STN DBS in PD.
Robertson, R. Kevin; Parsons, Thomas D.; Sidtis, John J.; Inman, Tina Hanlon; Robertson, Wendy T.; Hall, Colin D.; Price, Richard W.
Timed Gait Test: Normative Data for the Assessment of the AIDS Dementia Complex Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 28, pp. 1053–1064, 2006, ISSN: 1380-3395.
Abstract | Links | BibTeX | Tags: MedVR
@article{robertson_timed_2006,
title = {Timed Gait Test: Normative Data for the Assessment of the AIDS Dementia Complex},
author = {R. Kevin Robertson and Thomas D. Parsons and John J. Sidtis and Tina Hanlon Inman and Wendy T. Robertson and Colin D. Hall and Richard W. Price},
url = {http://ict.usc.edu/pubs/Timed%20Gait%20Test-%20Normative%20Data%20for%20the%20Assessment%20of%20the%20AIDS%20Dementia%20Complex.pdf},
doi = {10.1080/13803390500205684},
issn = {1380-3395},
year = {2006},
date = {2006-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {28},
pages = {1053–1064},
abstract = {The Timed Gait test is a standardized procedure assessing motor dysfunction of lower extremities and gait abnormalities associated with AIDS dementia complex. Heretofore, interpretations of Timed Gait results have been hampered by the lack of normative data. We provide results on this test derived from 1,549 subjects (HIV-seronegatives (HIV-) and seropositives (HIV+) classified according to ADC stage). Timed Gait was found to be a useful screening and assessment tool for evaluating ADC and correlated with clinical ADC staging as well as more extensive structured neurological and neuropsychological evaluations. Analysis of covariance results (with age and education as covariates) revealed symptomatic HIV+(SX) and AIDS groups having significantly slower Timed Gait scores than those in the HIV– and asymptomatic HIV+(ASX) groups. The SX group obtained significantly slower timed gait scores than those in the AIDS group. There was a significant increase in Timed Gait scores with each increase in dementia staging with the HIV- subjects having the fastest mean Timed Gait scores and the HIV+ dementia stage 2+ having the slowest. These normative data should prove useful in both recognition of ADC and treatment response. Given its minimal training requirements, the Timed Gait would have utility in resource limited settings.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The Timed Gait test is a standardized procedure assessing motor dysfunction of lower extremities and gait abnormalities associated with AIDS dementia complex. Heretofore, interpretations of Timed Gait results have been hampered by the lack of normative data. We provide results on this test derived from 1,549 subjects (HIV-seronegatives (HIV-) and seropositives (HIV+) classified according to ADC stage). Timed Gait was found to be a useful screening and assessment tool for evaluating ADC and correlated with clinical ADC staging as well as more extensive structured neurological and neuropsychological evaluations. Analysis of covariance results (with age and education as covariates) revealed symptomatic HIV+(SX) and AIDS groups having significantly slower Timed Gait scores than those in the HIV– and asymptomatic HIV+(ASX) groups. The SX group obtained significantly slower timed gait scores than those in the AIDS group. There was a significant increase in Timed Gait scores with each increase in dementia staging with the HIV- subjects having the fastest mean Timed Gait scores and the HIV+ dementia stage 2+ having the slowest. These normative data should prove useful in both recognition of ADC and treatment response. Given its minimal training requirements, the Timed Gait would have utility in resource limited settings.
2005
Morie, Jacquelyn; Iyer, Kumar; Luigi, Donat-Pierre; Williams, Josh; Dozois, Aimee; Rizzo, Albert
Development of a Data Management Tool for Investigating Multivariate Space and Free Will Experiences Journal Article
In: Applied Psychophysiology and Biofeedback, vol. 30, no. 3, pp. 319–331, 2005.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Worlds
@article{morie_development_2005,
title = {Development of a Data Management Tool for Investigating Multivariate Space and Free Will Experiences},
author = {Jacquelyn Morie and Kumar Iyer and Donat-Pierre Luigi and Josh Williams and Aimee Dozois and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Development%20of%20a%20Data%20Management%20Tool%20for%20Investigating%20Multivariate%20Space%20and%20Free%20Will%20Experiences%20in%20Virtual%20Reality.pdf},
year = {2005},
date = {2005-09-01},
journal = {Applied Psychophysiology and Biofeedback},
volume = {30},
number = {3},
pages = {319–331},
abstract = {While achieving realism has been a main goal in making convincing virtual reality (VR) environments, just what constitutes realism is still a question situated firmly in the research domain. VR has become mature enough to be used in therapeutic applications such as clinical exposure therapy with some success. We now need detailed scientific investigations to better understand why VR works for these types of cases, and how it could work for other key applications such as training. Just as in real life, it appears that the factors will be complex and multi-variate, and this plethoric situation presents exceptional challenges to the VR researcher. We would not want to lessen VR’s ability to replicate real world conditions in order to more easily study it, however, for by doing so we may compromise the very qualities that comprise its effectiveness. What is really needed are more robust tools to instrument, organize, and visualize the complex data generated by measurements of participant experiences in a realistic virtual world. We describe here our first study in an ongoing program of effective virtual environment research, the types of data we are dealing with, and a specific tool we have been compelled to create that allows us some measure of control over this data. We call this tool Phloem, after the botanical channels that plants use to transport, support and store nutrients.},
keywords = {MedVR, Virtual Worlds},
pubstate = {published},
tppubtype = {article}
}
While achieving realism has been a main goal in making convincing virtual reality (VR) environments, just what constitutes realism is still a question situated firmly in the research domain. VR has become mature enough to be used in therapeutic applications such as clinical exposure therapy with some success. We now need detailed scientific investigations to better understand why VR works for these types of cases, and how it could work for other key applications such as training. Just as in real life, it appears that the factors will be complex and multi-variate, and this plethoric situation presents exceptional challenges to the VR researcher. We would not want to lessen VR’s ability to replicate real world conditions in order to more easily study it, however, for by doing so we may compromise the very qualities that comprise its effectiveness. What is really needed are more robust tools to instrument, organize, and visualize the complex data generated by measurements of participant experiences in a realistic virtual world. We describe here our first study in an ongoing program of effective virtual environment research, the types of data we are dealing with, and a specific tool we have been compelled to create that allows us some measure of control over this data. We call this tool Phloem, after the botanical channels that plants use to transport, support and store nutrients.
Rizzo, Albert; Kim, Gerard J.; Yeh, Shih-Ching; Thiebaux, Marcus; Hwang, Jayne; Buckwalter, John Galen
Development of a Benchmarking Scenario for Testing 3D User Interface Devices and Interaction Methods Proceedings Article
In: Proceedings of the 11th International Conference on Human Computer Interaction, Las Vegas, NV, 2005.
Abstract | Links | BibTeX | Tags: MedVR
@inproceedings{rizzo_development_2005,
title = {Development of a Benchmarking Scenario for Testing 3D User Interface Devices and Interaction Methods},
author = {Albert Rizzo and Gerard J. Kim and Shih-Ching Yeh and Marcus Thiebaux and Jayne Hwang and John Galen Buckwalter},
url = {http://ict.usc.edu/pubs/Development%20of%20a%20Benchmarking%20Scenario%20for%20Testing%203D%20User%20Interface%20Devices%20and%20Interaction%20Methods.pdf},
year = {2005},
date = {2005-07-01},
booktitle = {Proceedings of the 11th International Conference on Human Computer Interaction},
address = {Las Vegas, NV},
abstract = {To address a part of the challenge of testing and comparing various 3D user interface devices and methods, we are currently developing and testing a VR 3D User Interface benchmarking scenario. The approach outlined in this paper focuses on the capture of human interaction performance on object selection and manipulation tasks using standardized and scalable block configurations that allow for measurement of speed and efficiency with any interaction device or method. The block configurations that we are using as benchmarking stimuli are accompanied by a pure mental rotation visuospatial assessment test. This feature will allow researchers to test usersX existing spatial abilities and statistically parcel out the variability due to innate ability, from the actual hands-on performance metrics. This statistical approach could lead to a more pure analysis of the ergonomic features of interaction devices and methods separate from existing user abilities. An initial test was conducted at two sites using this benchmarking system to make comparisons between 3D/gesture-based and 2D/mouse-based interactions for 3D selection and manipulation. Our preliminary results demonstrated, as expected, that the 3D/gesture based method in general outperformed the 2D/mouse interface. As well there were statistically significant performance differences between different user groups when categorized by their sex, visuospatial ability and educational background.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {inproceedings}
}
To address a part of the challenge of testing and comparing various 3D user interface devices and methods, we are currently developing and testing a VR 3D User Interface benchmarking scenario. The approach outlined in this paper focuses on the capture of human interaction performance on object selection and manipulation tasks using standardized and scalable block configurations that allow for measurement of speed and efficiency with any interaction device or method. The block configurations that we are using as benchmarking stimuli are accompanied by a pure mental rotation visuospatial assessment test. This feature will allow researchers to test usersX existing spatial abilities and statistically parcel out the variability due to innate ability, from the actual hands-on performance metrics. This statistical approach could lead to a more pure analysis of the ergonomic features of interaction devices and methods separate from existing user abilities. An initial test was conducted at two sites using this benchmarking system to make comparisons between 3D/gesture-based and 2D/mouse-based interactions for 3D selection and manipulation. Our preliminary results demonstrated, as expected, that the 3D/gesture based method in general outperformed the 2D/mouse interface. As well there were statistically significant performance differences between different user groups when categorized by their sex, visuospatial ability and educational background.
Alpaslan, Z. Y.; Yeh, S. -C.; Rizzo, Albert; Sawchuk, Alexander A.
Quantitative Comparison of Interaction with Shutter Glasses and Autostereoscopic Displays Proceedings Article
In: Stereoscopic Displays and Virtual Reality Systems XII Symposium, San Jose, CA, 2005.
Abstract | Links | BibTeX | Tags: MedVR
@inproceedings{alpaslan_quantitative_2005,
title = {Quantitative Comparison of Interaction with Shutter Glasses and Autostereoscopic Displays},
author = {Z. Y. Alpaslan and S. -C. Yeh and Albert Rizzo and Alexander A. Sawchuk},
url = {http://ict.usc.edu/pubs/Quantitative%20Comparison%20of%20Interaction%20with%20Shutter%20Glasses%20and%20Autostereoscopic%20Displays.pdf},
year = {2005},
date = {2005-01-01},
booktitle = {Stereoscopic Displays and Virtual Reality Systems XII Symposium},
address = {San Jose, CA},
abstract = {In this paper we describe experimental measurements and comparison of human interaction with three different types of stereo computer displays. We compare traditional shutter glasses-based viewing with three-dimensional (3D) autostereoscopic viewing on displays such as the Sharp LL-151-3D display and StereoGraphics SG 202 display. The method of interaction is a sphere-shaped "cyberprop" containing an Ascension Flock-of-Birds tracker that allows a user to manipulate objects by imparting the motion of the sphere to the virtual object. The tracking data is processed with OpenGL to manipulate objects in virtual 3D space, from which we synthesize two or more images as seen by virtual cameras observing them. We concentrate on the quantitative measurement and analysis of human performance for interactive object selection and manipulation tasks using standardized and scalable configurations of 3D block objects. The experiments use a series of progressively more complex block configurations that are rendered in stereo on various 3D displays. In general, performing the tasks using shutter glasses required less time as compared to using the autostereoscopic displays. While both male and female subjects performed almost equally fast with shutter glasses, male subjects performed better with the LL-151-3D display, while female subjects performed better with the SG202 display. Interestingly, users generally had a slightly higher efficiency in completing a task set using the two autostereoscopic displays as compared to the shutter glasses, although the differences for all users among the displays was relatively small. There was a preference for shutter glasses compared to autostereoscopic displays in the ease of performing tasks, and glasses were slightly preferred for overall image quality and stereo image quality. However, there was little difference in display preference in physical comfort and overall preference. We present some possible explanations of these results and point out the importance of the autostereoscopic "sweet spot" in relation to the user's head and body position.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {inproceedings}
}
In this paper we describe experimental measurements and comparison of human interaction with three different types of stereo computer displays. We compare traditional shutter glasses-based viewing with three-dimensional (3D) autostereoscopic viewing on displays such as the Sharp LL-151-3D display and StereoGraphics SG 202 display. The method of interaction is a sphere-shaped "cyberprop" containing an Ascension Flock-of-Birds tracker that allows a user to manipulate objects by imparting the motion of the sphere to the virtual object. The tracking data is processed with OpenGL to manipulate objects in virtual 3D space, from which we synthesize two or more images as seen by virtual cameras observing them. We concentrate on the quantitative measurement and analysis of human performance for interactive object selection and manipulation tasks using standardized and scalable configurations of 3D block objects. The experiments use a series of progressively more complex block configurations that are rendered in stereo on various 3D displays. In general, performing the tasks using shutter glasses required less time as compared to using the autostereoscopic displays. While both male and female subjects performed almost equally fast with shutter glasses, male subjects performed better with the LL-151-3D display, while female subjects performed better with the SG202 display. Interestingly, users generally had a slightly higher efficiency in completing a task set using the two autostereoscopic displays as compared to the shutter glasses, although the differences for all users among the displays was relatively small. There was a preference for shutter glasses compared to autostereoscopic displays in the ease of performing tasks, and glasses were slightly preferred for overall image quality and stereo image quality. However, there was little difference in display preference in physical comfort and overall preference. We present some possible explanations of these results and point out the importance of the autostereoscopic "sweet spot" in relation to the user's head and body position.
Rizzo, Albert; Pair, Jarrell; McNerney, Peter J.; Eastlund, Ernie; Manson, Brian; Gratch, Jonathan; Hill, Randall W.; Swartout, William
Development of a VR Therapy Application for Iraq War Military Personnel with PTSD Book Section
In: Studies in Health Technology and Informatics, vol. 111, no. 13, pp. 407+413, 13th Annual Medicine Meets Virtual Reality Conference, Long Beach, CA, 2005.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans
@incollection{rizzo_development_2005-1,
title = {Development of a VR Therapy Application for Iraq War Military Personnel with PTSD},
author = {Albert Rizzo and Jarrell Pair and Peter J. McNerney and Ernie Eastlund and Brian Manson and Jonathan Gratch and Randall W. Hill and William Swartout},
url = {http://ict.usc.edu/pubs/Development%20of%20a%20VR%20Therapy%20Application%20for%20Iraq%20War%20Veterans%20with%20PTSD.pdf},
year = {2005},
date = {2005-01-01},
booktitle = {Studies in Health Technology and Informatics},
volume = {111},
number = {13},
pages = {407+413},
address = {13th Annual Medicine Meets Virtual Reality Conference, Long Beach, CA},
series = {Medicine Meets Virtual Reality},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 returning Iraq War military personnel are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure therapy has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to specify the rationale, design and development of an Iraq War PTSD VR application that is being created from the virtual assets that were initially developed for theX-Box game entitled Full Spectrum Warrior which was inspired by a combat tactical training simulation, Full Spectrum Command.},
keywords = {MedVR, Virtual Humans},
pubstate = {published},
tppubtype = {incollection}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 returning Iraq War military personnel are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure therapy has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to specify the rationale, design and development of an Iraq War PTSD VR application that is being created from the virtual assets that were initially developed for theX-Box game entitled Full Spectrum Warrior which was inspired by a combat tactical training simulation, Full Spectrum Command.
Parsons, Thomas D.; Rizzo, Albert; Zaag, Cheryl; McGee, Jocelyn; Buckwalter, John Galen
Gender Differences and Cognition Among Older Adults Journal Article
In: Aging, Neuropsychology, and Cognition, vol. 12, pp. 78–88, 2005.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_gender_2005,
title = {Gender Differences and Cognition Among Older Adults},
author = {Thomas D. Parsons and Albert Rizzo and Cheryl Zaag and Jocelyn McGee and John Galen Buckwalter},
url = {http://ict.usc.edu/pubs/Gender%20Differences%20and%20Cognition%20Among%20Older%20Adults.pdf},
year = {2005},
date = {2005-01-01},
journal = {Aging, Neuropsychology, and Cognition},
volume = {12},
pages = {78–88},
abstract = {The more replicated findings about gender difference in cognitive performance suggest female superiority on visuomotor speed and language ability and male superiority on mechanical and visuospatial tasks. Generally, group strengths found in the early school years become more established at adolescence and remain stable through adulthood. The current study tested whether the patterns established in the early years remained among 30 adult subjects. We also utilized a series of exploratory analyses to determine if observed gender differences were impacted by the covariance present between all cognitive tests. Results suggest that although the patterns established in the early years remain stable through time for males, the established patterns for females are altered with age. Our findings are compelling in supporting a male advantage on visuospatial tasks among older adults. These findings are discussed in terms of common variance between test instruments as a possible source of difference. Our finding that the gender effect tended to increase when common variance was controlled argues that this methodology may enhance the ability to detect domain specific effects.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The more replicated findings about gender difference in cognitive performance suggest female superiority on visuomotor speed and language ability and male superiority on mechanical and visuospatial tasks. Generally, group strengths found in the early school years become more established at adolescence and remain stable through adulthood. The current study tested whether the patterns established in the early years remained among 30 adult subjects. We also utilized a series of exploratory analyses to determine if observed gender differences were impacted by the covariance present between all cognitive tests. Results suggest that although the patterns established in the early years remain stable through time for males, the established patterns for females are altered with age. Our findings are compelling in supporting a male advantage on visuospatial tasks among older adults. These findings are discussed in terms of common variance between test instruments as a possible source of difference. Our finding that the gender effect tended to increase when common variance was controlled argues that this methodology may enhance the ability to detect domain specific effects.
Robertson, R. Kevin; Mielke, Jens; Appiah, Kuku; Hall, Colin D.; Price, Richard W.; Kumwenda, Johnstone; Kanyama, Cecelia; Amod, Farida; Marra, Christina; Taylor, Terrie; Lalloo, Umesh; Jelsma, Jennifer; Holding, Penny; Boivin, Michael; Birbeck, Gretchen; Nakasujja, Noeline; Sanne, Ian; Parsons, Thomas D.; Parente, Amanda; Tucker, Karen A.
Assessment of neuroAIDS in Africa Journal Article
In: Journal of NeuroVirology, vol. 11, no. S1, pp. 7–16, 2005.
Abstract | Links | BibTeX | Tags: MedVR
@article{robertson_assessment_2005,
title = {Assessment of neuroAIDS in Africa},
author = {R. Kevin Robertson and Jens Mielke and Kuku Appiah and Colin D. Hall and Richard W. Price and Johnstone Kumwenda and Cecelia Kanyama and Farida Amod and Christina Marra and Terrie Taylor and Umesh Lalloo and Jennifer Jelsma and Penny Holding and Michael Boivin and Gretchen Birbeck and Noeline Nakasujja and Ian Sanne and Thomas D. Parsons and Amanda Parente and Karen A. Tucker},
url = {http://ict.usc.edu/pubs/Assessment%20of%20neuroAIDS%20in%20Africa.pdf},
year = {2005},
date = {2005-01-01},
journal = {Journal of NeuroVirology},
volume = {11},
number = {S1},
pages = {7–16},
abstract = {In June of 2004, the Center for AIDS Mental Health Research, National Institute of Mental Health sponsored a conference on the Assessment of NeuroAIDS in Africa, which was held in Blantrye, Malawai. The conference presentations summarized here highlight the need for research on NeuroAIDS in Africa and methods for assessing HIV-related neurological diseases (Robertson, 2004).},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
In June of 2004, the Center for AIDS Mental Health Research, National Institute of Mental Health sponsored a conference on the Assessment of NeuroAIDS in Africa, which was held in Blantrye, Malawai. The conference presentations summarized here highlight the need for research on NeuroAIDS in Africa and methods for assessing HIV-related neurological diseases (Robertson, 2004).
Rizzo, Albert; Morie, Jacquelyn; Williams, Josh; Pair, Jarrell; Buckwalter, John Galen
Human Emotional State and its Relevance for Military VR Training Proceedings Article
In: Proceedings of the 11th International Conference on Human-Computer Interaction, Las Vegas, NV, 2005.
Abstract | Links | BibTeX | Tags: MedVR, Virtual Humans, Virtual Worlds
@inproceedings{rizzo_human_2005,
title = {Human Emotional State and its Relevance for Military VR Training},
author = {Albert Rizzo and Jacquelyn Morie and Josh Williams and Jarrell Pair and John Galen Buckwalter},
url = {http://ict.usc.edu/pubs/Human%20Emotional%20State%20and%20its%20Relevance%20for%20Military%20VR%20Training.pdf},
year = {2005},
date = {2005-01-01},
booktitle = {Proceedings of the 11th International Conference on Human-Computer Interaction},
address = {Las Vegas, NV},
abstract = {Combat environments by their nature can produce a dramatic range of emotional responses in military personnel. When immersed in the emotional "fog of war," the potential exists for optimal human decision-making and performance of goal-directed activities to be seriously compromised. This may be especially true when combat training is conducted under conditions that lack emotional engagement by the soldier. Real world military training often naturally includes stress induction that aims to promote a similarity of internal emotional stimulus cues with what is expected to be present on the battlefield. This approach to facilitating optimal training effectiveness is supported by a long history of learning theory research. Current Virtual Reality military training approaches are noteworthy in their emphasis on creating hi-fidelity graphic and audio realism with the aim to foster better transfer of training. However, less emphasis is typically placed on the creation of emotionally evocative virtual training scenarios that can induce emotional stress in a manner similar to what is typically experienced under real world training conditions. As well, emotional issues in the post-combat aftermath need to be addressed, as can be seen in the devastating emotional difficulties that occur in some military personnel following combat. This is evidenced by the number of recent medical reports that suggest the incidence of "Vietnam-levels" of combat-related Post Traumatic Stress Disorder symptomatology in returning military personnel from the Iraq conflict. In view of these issues, the USC Institute for Creative Technologies (ICT) has initiated a research program to study emotional issues that are relevant to VR military applications. This paper will present the rationale and status of two ongoing VR research programs at the ICT that address sharply contrasting ends of the emotional spectrum relevant to the military: 1. The Sensory Environments Evaluation (SEE) Project is examining basic factors that underlie emotion as it occurs within VR training environments and how this could impact transfer of training, and 2. The Full Spectrum Warrior (FSW) Post Traumatic Stress Disorder Project which is currently in the process of converting the existing FSW combat tactical simulation training scenario (and X-Box game) into a VR treatment system for the conduct of graduated exposure therapy in Iraq war military personnel with Post Traumatic Stress Disorder.},
keywords = {MedVR, Virtual Humans, Virtual Worlds},
pubstate = {published},
tppubtype = {inproceedings}
}
Combat environments by their nature can produce a dramatic range of emotional responses in military personnel. When immersed in the emotional "fog of war," the potential exists for optimal human decision-making and performance of goal-directed activities to be seriously compromised. This may be especially true when combat training is conducted under conditions that lack emotional engagement by the soldier. Real world military training often naturally includes stress induction that aims to promote a similarity of internal emotional stimulus cues with what is expected to be present on the battlefield. This approach to facilitating optimal training effectiveness is supported by a long history of learning theory research. Current Virtual Reality military training approaches are noteworthy in their emphasis on creating hi-fidelity graphic and audio realism with the aim to foster better transfer of training. However, less emphasis is typically placed on the creation of emotionally evocative virtual training scenarios that can induce emotional stress in a manner similar to what is typically experienced under real world training conditions. As well, emotional issues in the post-combat aftermath need to be addressed, as can be seen in the devastating emotional difficulties that occur in some military personnel following combat. This is evidenced by the number of recent medical reports that suggest the incidence of "Vietnam-levels" of combat-related Post Traumatic Stress Disorder symptomatology in returning military personnel from the Iraq conflict. In view of these issues, the USC Institute for Creative Technologies (ICT) has initiated a research program to study emotional issues that are relevant to VR military applications. This paper will present the rationale and status of two ongoing VR research programs at the ICT that address sharply contrasting ends of the emotional spectrum relevant to the military: 1. The Sensory Environments Evaluation (SEE) Project is examining basic factors that underlie emotion as it occurs within VR training environments and how this could impact transfer of training, and 2. The Full Spectrum Warrior (FSW) Post Traumatic Stress Disorder Project which is currently in the process of converting the existing FSW combat tactical simulation training scenario (and X-Box game) into a VR treatment system for the conduct of graduated exposure therapy in Iraq war military personnel with Post Traumatic Stress Disorder.
Rizzo, Albert; Klimchuck, Dean; Mitura, Roman; Bowerly, Todd; Buckwalter, John Galen; Kerns, Kim; Randall, Karherine; Adams, Rebecca; Finn, Paul; Tarnanas, Ioannis; Sirbu, Cristian; Ollendick, Thomas H.; Yeh, Shih-Ching
A Virtual Reality Scenario for All Seasons: The Virtual Classroom Proceedings Article
In: Proceedings of the 11th International Conference on Human Computer Interaction, Las Vegas, NV, 2005.
Abstract | Links | BibTeX | Tags: MedVR
@inproceedings{rizzo_virtual_2005,
title = {A Virtual Reality Scenario for All Seasons: The Virtual Classroom},
author = {Albert Rizzo and Dean Klimchuck and Roman Mitura and Todd Bowerly and John Galen Buckwalter and Kim Kerns and Karherine Randall and Rebecca Adams and Paul Finn and Ioannis Tarnanas and Cristian Sirbu and Thomas H. Ollendick and Shih-Ching Yeh},
url = {http://ict.usc.edu/pubs/A%20Virtual%20Reality%20Scenario%20for%20All%20Seasons-%20The%20Virtual%20Classroom%20(HCI).pdf},
year = {2005},
date = {2005-01-01},
booktitle = {Proceedings of the 11th International Conference on Human Computer Interaction},
address = {Las Vegas, NV},
abstract = {Rather than relying on costly physical mock-ups of functional assessment and rehabilitation environments, VR offers the option to produce and distribute identical "standard" environments. Within such digital assessment and rehabilitation scenarios, normative data can be accumulated for performance comparisons needed for assessment, diagnosis and for training purposes. As well, in this manner, reusable archetypic virtual environments constructed for one purpose, could also be applied for clinical applications addressing other purposes. This has now been done with the Virtual Classroom scenario. While originally developed as a controlled stimulus environment in which attention processes could be systematically assessed in children while in the presence of varying levels of distraction, the system is now finding use for other clinical targets. Such applications that are being developed and tested using the Virtual Classroom for other purposes include: 1. Expansion of the range of attention assessment tests (i.e., a _Stroop` Interference testing system for all ages). 2. A wide field of view system to study eye tracking under distracting conditions with ADHD children using an Elumens VisionStation®. 3. Development of the Virtual Classroom as a tool for anxiety assessment and graduated exposure therapy for children with Social Anxiety Disorder. 4. An extension to the class to include a maze of halls leading out of the school for an earthquake safety training application with persons with developmental and learning disabilities.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {inproceedings}
}
Rather than relying on costly physical mock-ups of functional assessment and rehabilitation environments, VR offers the option to produce and distribute identical "standard" environments. Within such digital assessment and rehabilitation scenarios, normative data can be accumulated for performance comparisons needed for assessment, diagnosis and for training purposes. As well, in this manner, reusable archetypic virtual environments constructed for one purpose, could also be applied for clinical applications addressing other purposes. This has now been done with the Virtual Classroom scenario. While originally developed as a controlled stimulus environment in which attention processes could be systematically assessed in children while in the presence of varying levels of distraction, the system is now finding use for other clinical targets. Such applications that are being developed and tested using the Virtual Classroom for other purposes include: 1. Expansion of the range of attention assessment tests (i.e., a _Stroop` Interference testing system for all ages). 2. A wide field of view system to study eye tracking under distracting conditions with ADHD children using an Elumens VisionStation®. 3. Development of the Virtual Classroom as a tool for anxiety assessment and graduated exposure therapy for children with Social Anxiety Disorder. 4. An extension to the class to include a maze of halls leading out of the school for an earthquake safety training application with persons with developmental and learning disabilities.
Grote, Christopher L.; Parsons, Thomas D.
Threats to the Livelihood of the Forensic Neuropsychological Practice: Avoiding Ethical Misconduct Journal Article
In: Journal of Forensic Neuropsychology, vol. 4, no. 3, pp. 79–93, 2005.
Abstract | Links | BibTeX | Tags: MedVR
@article{grote_threats_2005,
title = {Threats to the Livelihood of the Forensic Neuropsychological Practice: Avoiding Ethical Misconduct},
author = {Christopher L. Grote and Thomas D. Parsons},
url = {http://ict.usc.edu/pubs/Threats%20to%20the%20Livelihood%20of%20the%20Forensic%20Neuropsychological%20Practice-%20Avoiding%20Ethical%20Misconduct.pdf},
doi = {10.1300/J151v04n03_06},
year = {2005},
date = {2005-01-01},
journal = {Journal of Forensic Neuropsychology},
volume = {4},
number = {3},
pages = {79–93},
abstract = {We review six diverse issues that have the potential of devaluing our profession, in that ethical missteps could lead to the perception or reality that the work of forensic neuropsychologists is "for sale." By resisting temptations or overtures to engage in inappropriate conduct, such as attacking colleagues or failing to recognize how our own biases might influence our behavior or opinions, neuropsychologists strive to create a work product that enhances the reputation of our profession and makes a positive contribution to the public-at-large.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
We review six diverse issues that have the potential of devaluing our profession, in that ethical missteps could lead to the perception or reality that the work of forensic neuropsychologists is "for sale." By resisting temptations or overtures to engage in inappropriate conduct, such as attacking colleagues or failing to recognize how our own biases might influence our behavior or opinions, neuropsychologists strive to create a work product that enhances the reputation of our profession and makes a positive contribution to the public-at-large.
2004
Parsons, Thomas D.; Thompson, E.; Buckwalter, John Galen; Bluestein, Brendon
Pregnancy History and Cognition During and After Pregnancy Journal Article
In: International Journal of Neuroscience, vol. 114, pp. 1099–1110, 2004, ISSN: 0020-7454.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_pregnancy_2004,
title = {Pregnancy History and Cognition During and After Pregnancy},
author = {Thomas D. Parsons and E. Thompson and John Galen Buckwalter and Brendon Bluestein},
url = {http://ict.usc.edu/pubs/Pregnancy%20History%20and%20Cognition%20During%20and%20After%20Pregnancy.pdf},
doi = {10.1080/00207450490475544},
issn = {0020-7454},
year = {2004},
date = {2004-01-01},
journal = {International Journal of Neuroscience},
volume = {114},
pages = {1099–1110},
abstract = {An increasing body of literature confirms anecdotal reports that cognitive changes occur during pregnancy. This article assessed whether prior pregnancy, which alters a woman's subsequent hormonal environment, is associated with a specific cognitive profile during and after pregnancy. Seven primigravids and nine multigravids were compared, equivalent for age and education. No differences between groups were found during pregnancy. After delivery, multigravids performed better than primigravids on verbal memory tasks. After controlling for mood, a significant difference in verbal memory remained. A neuroadaptive mechanism may develop after first pregnancy that increases the ability to recover from some cognitive deficits after later pregnancies.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
An increasing body of literature confirms anecdotal reports that cognitive changes occur during pregnancy. This article assessed whether prior pregnancy, which alters a woman's subsequent hormonal environment, is associated with a specific cognitive profile during and after pregnancy. Seven primigravids and nine multigravids were compared, equivalent for age and education. No differences between groups were found during pregnancy. After delivery, multigravids performed better than primigravids on verbal memory tasks. After controlling for mood, a significant difference in verbal memory remained. A neuroadaptive mechanism may develop after first pregnancy that increases the ability to recover from some cognitive deficits after later pregnancies.
Parsons, Thomas D.; Larson, Peter; Kratz, Kris; Thiebaux, Marcus; Bluestein, Brendon; Buckwalter, John Galen; Rizzo, Albert
Sex differences in mental rotation and spatial rotation in a virtual environment Journal Article
In: Neuropsychologia, vol. 42, pp. 555–562, 2004.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_sex_2004,
title = {Sex differences in mental rotation and spatial rotation in a virtual environment},
author = {Thomas D. Parsons and Peter Larson and Kris Kratz and Marcus Thiebaux and Brendon Bluestein and John Galen Buckwalter and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Sex%20differences%20in%20mental%20rotation%20and%20spatial%20rotation%20in%20a%20virtual%20environment.pdf},
doi = {10.1016/j.neuropsychologia.2003.08.014},
year = {2004},
date = {2004-01-01},
journal = {Neuropsychologia},
volume = {42},
pages = {555–562},
abstract = {The visuospatial ability referred to as mental rotation has been shown to produce one of the largest and most consistent sex differences, in favor of males, in the cognitive literature. The current study utilizes both a paper-and-pencil version of the mental rotations test (MRT) and a virtual environment for investigating rotational ability among 44 adult subjects. Results replicate sex differences traditionally seen on paper-and-pencil measures, while no sex effects were observed in the virtual environment. These ï¬ndings are discussed in terms of task demands and motor involvement. Sex differences were also seen in the patterns of correlations between rotation tasks and other neuropsychological measures. Current results suggest men may rely more on left hemisphere processing than women when engaged in rotational tasks. © 2003 Elsevier Ltd. All rights reserved.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The visuospatial ability referred to as mental rotation has been shown to produce one of the largest and most consistent sex differences, in favor of males, in the cognitive literature. The current study utilizes both a paper-and-pencil version of the mental rotations test (MRT) and a virtual environment for investigating rotational ability among 44 adult subjects. Results replicate sex differences traditionally seen on paper-and-pencil measures, while no sex effects were observed in the virtual environment. These ï¬ndings are discussed in terms of task demands and motor involvement. Sex differences were also seen in the patterns of correlations between rotation tasks and other neuropsychological measures. Current results suggest men may rely more on left hemisphere processing than women when engaged in rotational tasks. © 2003 Elsevier Ltd. All rights reserved.
Parsons, Thomas D.; Rizzo, Albert; Buckwalter, John Galen
Backpropagation and Regression: Comparative Utility for Neuropsychologists Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 26, no. 1, pp. 95–104, 2004.
Abstract | Links | BibTeX | Tags: MedVR
@article{parsons_backpropagation_2004,
title = {Backpropagation and Regression: Comparative Utility for Neuropsychologists},
author = {Thomas D. Parsons and Albert Rizzo and John Galen Buckwalter},
url = {http://ict.usc.edu/pubs/Backpropagation%20and%20Regression-%20Comparative%20Utility%20for%20Neuropsychologists.pdf},
year = {2004},
date = {2004-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {26},
number = {1},
pages = {95–104},
abstract = {The aim of this research was to compare the data analytic applicability of a backpropagated neural network with that of regression analysis. Thirty individuals between the ages of 64 and 86 (Mean age = 73.6; Mean years education = 15.4; % women = 50) participated in a study designed to validate a new test of spatial ability administered in virtual reality. As part of this project a standard neuropsychological battery was administered. Results from the multiple regression model (R2 = .21, p textbackslashtextbackslashtextbackslashtextbackslashtextless .28; Standard Error = 18.01) were compared with those of a backpropagated ANN (R2 = .39, p textbackslashtextbackslashtextbackslashtextbackslashtextless .02; Standard Error = 13.07). This 18% increase in prediction of a common neuropsychological problem demonstrated that an ANN has the potential to outperform a regression.},
keywords = {MedVR},
pubstate = {published},
tppubtype = {article}
}
The aim of this research was to compare the data analytic applicability of a backpropagated neural network with that of regression analysis. Thirty individuals between the ages of 64 and 86 (Mean age = 73.6; Mean years education = 15.4; % women = 50) participated in a study designed to validate a new test of spatial ability administered in virtual reality. As part of this project a standard neuropsychological battery was administered. Results from the multiple regression model (R2 = .21, p textbackslashtextbackslashtextbackslashtextbackslashtextless .28; Standard Error = 18.01) were compared with those of a backpropagated ANN (R2 = .39, p textbackslashtextbackslashtextbackslashtextbackslashtextless .02; Standard Error = 13.07). This 18% increase in prediction of a common neuropsychological problem demonstrated that an ANN has the potential to outperform a regression.
0000
Hartholt, Arno; Mozgai, Sharon
From Combat to COVID-19 – Managing the Impact of Trauma Using Virtual Reality Journal Article
In: pp. 35, 0000.
Abstract | BibTeX | Tags: DTIC, MedVR, Virtual Humans, VR
@article{hartholt_combat_nodate,
title = {From Combat to COVID-19 – Managing the Impact of Trauma Using Virtual Reality},
author = {Arno Hartholt and Sharon Mozgai},
pages = {35},
abstract = {Research has documented the efficacy of clinical applications that leverage Virtual Reality (VR) for assessment and treatment purposes across a wide range of domains, including pain, phobias, and posttraumatic stress disorder (PTSD). As the field of Clinical VR matures, it is important to review its origins and examine how these initial explorations have progressed, what gaps remain, and what opportunities the community can pursue. We do this by reflecting on our personal scientific journey against the backdrop of the field in general. In particular, this paper discusses how a clinical research program that was initially designed to deliver trauma-focused VR exposure therapy (VRET) for combat-related PTSD has been evolved to expand its impact and address a wider range of trauma sources. Such trauma sources include sexual trauma and the needs of first responders and healthcare professionals serving on the frontlines of the COVID-19 pandemic. We provide an overview of the field and its general trends, discuss the genesis of our research agenda and its current status, and summarize upcoming opportunities, together with common challenges and lessons learned.},
keywords = {DTIC, MedVR, Virtual Humans, VR},
pubstate = {published},
tppubtype = {article}
}
Research has documented the efficacy of clinical applications that leverage Virtual Reality (VR) for assessment and treatment purposes across a wide range of domains, including pain, phobias, and posttraumatic stress disorder (PTSD). As the field of Clinical VR matures, it is important to review its origins and examine how these initial explorations have progressed, what gaps remain, and what opportunities the community can pursue. We do this by reflecting on our personal scientific journey against the backdrop of the field in general. In particular, this paper discusses how a clinical research program that was initially designed to deliver trauma-focused VR exposure therapy (VRET) for combat-related PTSD has been evolved to expand its impact and address a wider range of trauma sources. Such trauma sources include sexual trauma and the needs of first responders and healthcare professionals serving on the frontlines of the COVID-19 pandemic. We provide an overview of the field and its general trends, discuss the genesis of our research agenda and its current status, and summarize upcoming opportunities, together with common challenges and lessons learned.