Publications
Search
261.
Robertson, R. Kevin; Nakasujja, Noeline; Wong, Matthew; Musisi, Seggane; Katabira, Elly; Parsons, Thomas D.; Ronald, Allan; Sacktor, Ned
Pattern of neuropsychological performance among HIV positive patients in Uganda Journal Article
In: BMC Neurology, 2007.
@article{robertson_pattern_2007,
title = {Pattern of neuropsychological performance among HIV positive patients in Uganda},
author = {R. Kevin Robertson and Noeline Nakasujja and Matthew Wong and Seggane Musisi and Elly Katabira and Thomas D. Parsons and Allan Ronald and Ned Sacktor},
url = {http://ict.usc.edu/pubs/Pattern%20of%20neuropsychological%20performance%20among%20HIV%20positive%20patients%20in%20Uganda.pdf},
year = {2007},
date = {2007-04-01},
journal = {BMC Neurology},
abstract = {Few studies have examined cognitive functioning of HIV positive patients in sub-Saharan Africa. It cannot be assumed that HIV positive patients in Africa exhibit the same declines as patients in high-resource settings, since there are differences that may influence cognitive functioning including nutrition, history of concomitant disease, and varying HIV strains, among other possibilities. Part of the difficulty of specifying abnormalities in neuropsychological functioning among African HIV positive patients is that there are no readily available African normative databases. The purpose of the current study was to evaluate the pattern of neuropsychological performance in a sample of HIV positive patients in comparison to HIV negative control subjects in Uganda. Methods: The neuropsychological test scores of 110 HIV positive patients (WHO Stage 2},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Few studies have examined cognitive functioning of HIV positive patients in sub-Saharan Africa. It cannot be assumed that HIV positive patients in Africa exhibit the same declines as patients in high-resource settings, since there are differences that may influence cognitive functioning including nutrition, history of concomitant disease, and varying HIV strains, among other possibilities. Part of the difficulty of specifying abnormalities in neuropsychological functioning among African HIV positive patients is that there are no readily available African normative databases. The purpose of the current study was to evaluate the pattern of neuropsychological performance in a sample of HIV positive patients in comparison to HIV negative control subjects in Uganda. Methods: The neuropsychological test scores of 110 HIV positive patients (WHO Stage 2
262.
Yeh, Shih-Ching; Rizzo, Albert; McLaughlin, Margaret; Parsons, Thomas D.
In: Studies in Health Technology and Informatics, vol. 125, pp. 506–511, 2007.
@article{yeh_vr_2007,
title = {VR Enhanced Upper Extremity Motor Training for Post-Stroke Rehabilitation: Task Design, Clinical Experiment and Visualization on Performance and Progress},
author = {Shih-Ching Yeh and Albert Rizzo and Margaret McLaughlin and Thomas D. Parsons},
url = {http://ict.usc.edu/pubs/VR%20Enhanced%20Upper%20Extremity%20Motor%20Training%20for%20Post-Stroke%20Rehabilitation-%20Task%20Design,%20Clinical%20Experiment%20and%20Visualization%20on%20Performance%20and%20Progress.pdf},
year = {2007},
date = {2007-01-01},
journal = {Studies in Health Technology and Informatics},
volume = {125},
pages = {506–511},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
263.
Yeh, Shih-Ching; Stewart, Jill; McLaughlin, Margaret; Parsons, Thomas D.; Winstein, Carolee J.; Rizzo, Albert
Evaluation Approach for Post-stroke Rehabilitation Via Virtual Reality Aided Motor Training Proceedings Article
In: Lecture Notes in Computer Science, pp. 378–387, 2007, 2007.
@inproceedings{yeh_evaluation_2007,
title = {Evaluation Approach for Post-stroke Rehabilitation Via Virtual Reality Aided Motor Training},
author = {Shih-Ching Yeh and Jill Stewart and Margaret McLaughlin and Thomas D. Parsons and Carolee J. Winstein and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Evaluation%20Approach%20for%20Post-stroke%20Rehabilitation%20Via%20Virtual%20Reality%20Aided%20Motor%20Training.pdf},
year = {2007},
date = {2007-01-01},
booktitle = {Lecture Notes in Computer Science},
pages = {378–387},
address = {2007},
abstract = {This paper introduces an evaluation approach that was applied to clinical data collected from a virtual reality aided motor training program for post-stroke rehabilitation. The goal of the proposed evaluation approach is to diagnose the patient's current status (performance) and detect change in status over time (progression). Three measures, performance time, movement efficiency, and movement speed, were defined to represent kinematic features of reaching. 3-D performance maps and progression maps were generated based on each kinematic measure to visualize a single patient's behavior. The case study revealed the patient's current status as to direction and range of upper extremity reach ability, composed of pitch, yaw and arm length. Further, progression was found and visualized quantitatively over a series of practice sessions.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
This paper introduces an evaluation approach that was applied to clinical data collected from a virtual reality aided motor training program for post-stroke rehabilitation. The goal of the proposed evaluation approach is to diagnose the patient's current status (performance) and detect change in status over time (progression). Three measures, performance time, movement efficiency, and movement speed, were defined to represent kinematic features of reaching. 3-D performance maps and progression maps were generated based on each kinematic measure to visualize a single patient's behavior. The case study revealed the patient's current status as to direction and range of upper extremity reach ability, composed of pitch, yaw and arm length. Further, progression was found and visualized quantitatively over a series of practice sessions.
264.
Kenny, Patrick G.; Parsons, Thomas D.; Gratch, Jonathan; Leuski, Anton; Rizzo, Albert
Virtual Patients for Clinical Therapist Skills Training Proceedings Article
In: Lecture Notes in Artificial Intelligence; Proceedings of the 7th International Conference on Intelligent Virtual Agents (IVA), pp. 197–210, Paris, France, 2007.
@inproceedings{kenny_virtual_2007-1,
title = {Virtual Patients for Clinical Therapist Skills Training},
author = {Patrick G. Kenny and Thomas D. Parsons and Jonathan Gratch and Anton Leuski and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Virtual%20Patients%20for%20Clinical%20Therapist%20Skills%20Training.pdf},
year = {2007},
date = {2007-01-01},
booktitle = {Lecture Notes in Artificial Intelligence; Proceedings of the 7th International Conference on Intelligent Virtual Agents (IVA)},
volume = {4722},
pages = {197–210},
address = {Paris, France},
abstract = {Virtual humans offer an exciting and powerful potential for rich interactive experiences. Fully embodied virtual humans are growing in capability, ease, and utility. As a result, they present an opportunity for expanding research into burgeoning virtual patient medical applications. In this paper we consider the ways in which one may go about building and applying virtual human technology to the virtual patient domain. Specifically we aim to show that virtual human technology may be used to help develop the interviewing and diagnostics skills of developing clinicians. Herein we proffer a description of our iterative design process and preliminary results to show that virtual patients may be a useful adjunct to psychotherapy education.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
Virtual humans offer an exciting and powerful potential for rich interactive experiences. Fully embodied virtual humans are growing in capability, ease, and utility. As a result, they present an opportunity for expanding research into burgeoning virtual patient medical applications. In this paper we consider the ways in which one may go about building and applying virtual human technology to the virtual patient domain. Specifically we aim to show that virtual human technology may be used to help develop the interviewing and diagnostics skills of developing clinicians. Herein we proffer a description of our iterative design process and preliminary results to show that virtual patients may be a useful adjunct to psychotherapy education.
265.
Parsons, Thomas D.; Bowerly, Todd; Buckwalter, John Galen; Rizzo, Albert
In: Child Neuropsychology, vol. 13, pp. 363–381, 2007.
@article{parsons_controlled_2007,
title = {A controlled clinical comparison of attention performance in children with ADHD in a virtual reality classroom compared to standard neuropsychological methods},
author = {Thomas D. Parsons and Todd Bowerly and John Galen Buckwalter and Albert Rizzo},
url = {http://ict.usc.edu/pubs/A%20CONTROLLED%20CLINICAL%20COMPARISON%20OF%20ATTENTION%20PERFORMANCE%20IN%20CHILDREN%20WITH%20ADHD%20IN%20A%20VIRTUAL%20REALITY%20CLASSROOM%20COMPARED%20TO%20STANDARD%20NEUROPSYCHOLOGICAL%20METHODS.pdf},
doi = {10.1080/13825580600943473},
year = {2007},
date = {2007-01-01},
journal = {Child Neuropsychology},
volume = {13},
pages = {363–381},
abstract = {In this initial pilot study, a controlled clinical comparison was made of attention performance in children with attention deficit-hyperactivity disorder (ADHD) in a virtual reality (VR) classroom. Ten boys diagnosed with ADHD and ten normal control boys participated in the study. Groups did not significantly differ in mean age, grade level, ethnicity, or handedness. No participants reported simulator sickness following VR exposure. Children with ADHD exhibited more omission errors, commission errors, and overall body movement than normal control children in the VR classroom. Children with ADHD were more impacted by distraction in the VR classroom. VR classroom measures were correlated with traditional ADHD assessment tools and the flatscreen CPT. Of note, the small sample size incorporated in each group and higher WISC-III scores of normal controls might have some bearing on the overall interpretation of results. These data suggested that the Virtual Classroom had good potential for controlled performance assessment within an ecologically valid environment and appeared to parse out significant effects due to the presence of distraction stimuli.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
In this initial pilot study, a controlled clinical comparison was made of attention performance in children with attention deficit-hyperactivity disorder (ADHD) in a virtual reality (VR) classroom. Ten boys diagnosed with ADHD and ten normal control boys participated in the study. Groups did not significantly differ in mean age, grade level, ethnicity, or handedness. No participants reported simulator sickness following VR exposure. Children with ADHD exhibited more omission errors, commission errors, and overall body movement than normal control children in the VR classroom. Children with ADHD were more impacted by distraction in the VR classroom. VR classroom measures were correlated with traditional ADHD assessment tools and the flatscreen CPT. Of note, the small sample size incorporated in each group and higher WISC-III scores of normal controls might have some bearing on the overall interpretation of results. These data suggested that the Virtual Classroom had good potential for controlled performance assessment within an ecologically valid environment and appeared to parse out significant effects due to the presence of distraction stimuli.
266.
Miller, Karen J.; Parsons, Thomas D.; Whybrow, Peter C.; Herle, Katja; Rasgon, Natalie; Herle, Andre; Martinez, Dorothy; Silverman, Dan H.; Bauer, Michael
Verbal Memory Retrieval Deficits Associated With Untreated Hypothyroidism Journal Article
In: Journal of Neuropsychiatry and Clinical Neurosciences, vol. 19, no. 2, pp. 132–136, 2007.
@article{miller_verbal_2007,
title = {Verbal Memory Retrieval Deficits Associated With Untreated Hypothyroidism},
author = {Karen J. Miller and Thomas D. Parsons and Peter C. Whybrow and Katja Herle and Natalie Rasgon and Andre Herle and Dorothy Martinez and Dan H. Silverman and Michael Bauer},
url = {http://ict.usc.edu/pubs/Verbal%20Memory%20Retrieval%20Deficits%20Associated%20With%20Untreated%20Hypothyroidism.pdf},
year = {2007},
date = {2007-01-01},
journal = {Journal of Neuropsychiatry and Clinical Neurosciences},
volume = {19},
number = {2},
pages = {132–136},
abstract = {The effects of inadequate thyroid hormone availability to the brain on adult cognitive function are poorly understood. This study assessed the effects of hypothyroidism on cognitive function using a standard neuropsychological battery in 14 patients suffering from untreated hypothyroidism and complaining of subjective cognitive difï¬culties in comparison with 10 age-matched healthy comparison subjects. Signiï¬cant differences between groups were limited to verbal memory retrieval as measured by the California Verbal Learning Test (CVLT). On short delay free recall, long delay free recall, and long delay cued recall, signiï¬cant differences remained between groups despite the limited statistical power of this study. There were no signiï¬cant results found between groups on attentional or nonverbal tasks. Results suggest that hypothyroid-related memory deï¬cits are not attributable to an attentional deï¬cit but rather to speciï¬c retrieval deï¬cits.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The effects of inadequate thyroid hormone availability to the brain on adult cognitive function are poorly understood. This study assessed the effects of hypothyroidism on cognitive function using a standard neuropsychological battery in 14 patients suffering from untreated hypothyroidism and complaining of subjective cognitive difï¬culties in comparison with 10 age-matched healthy comparison subjects. Signiï¬cant differences between groups were limited to verbal memory retrieval as measured by the California Verbal Learning Test (CVLT). On short delay free recall, long delay free recall, and long delay cued recall, signiï¬cant differences remained between groups despite the limited statistical power of this study. There were no signiï¬cant results found between groups on attentional or nonverbal tasks. Results suggest that hypothyroid-related memory deï¬cits are not attributable to an attentional deï¬cit but rather to speciï¬c retrieval deï¬cits.
267.
Robertson, R. Kevin; Parsons, Thomas D.; Rogers, Steven A.; Braaten, Alyssa J.; Robertson, Wendy T.; Wilson, Susan; Hall, Colin D.
Assessing health-related quality of life in NeuroAIDS: some psychometric properties of the Neurological Quality of Life Questionnaire (NeuroQOL) Journal Article
In: Journal of Clinical Neuroscience, vol. 14, pp. 416+423, 2007.
@article{robertson_assessing_2007,
title = {Assessing health-related quality of life in NeuroAIDS: some psychometric properties of the Neurological Quality of Life Questionnaire (NeuroQOL)},
author = {R. Kevin Robertson and Thomas D. Parsons and Steven A. Rogers and Alyssa J. Braaten and Wendy T. Robertson and Susan Wilson and Colin D. Hall},
url = {http://ict.usc.edu/pubs/Assessing%20health-related%20quality%20of%20life%20in%20NeuroAIDS-%20some%20psychometric%20properties%20of%20the%20Neurological%20Quality%20of%20Life%20Questionnaire%20(NeuroQOL).pdf},
year = {2007},
date = {2007-01-01},
journal = {Journal of Clinical Neuroscience},
volume = {14},
pages = {416+423},
abstract = {Several studies were undertaken to assess the psychometric properties (reliability and initial convergent and discriminant construct validity) of the Neurological Quality of Life Questionnaire (NeuroQOL). The NeuroQOL contains 114 items answered in self report Likert format, with higher scores reflecting better quality of life. Study one compared the questionnaire with existing quality of life measures (Symptom Distress Scale, Sickness Impact Profile) and disease stage, psychological, neuropsychological and neurological measures, and a significant correlation was also fount with each domain. The internal consistency reliability (alpha = 0.96), split half reliability (r12 = 0.97), and test-retest reliability (coefficients were 0.78 for 6 months and 0.67 for one year intervals between test and retest) were all found to high and adequately stable. Overall, these results indicate acceptable reliability and initial construct valididty for the NeuroQOL.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Several studies were undertaken to assess the psychometric properties (reliability and initial convergent and discriminant construct validity) of the Neurological Quality of Life Questionnaire (NeuroQOL). The NeuroQOL contains 114 items answered in self report Likert format, with higher scores reflecting better quality of life. Study one compared the questionnaire with existing quality of life measures (Symptom Distress Scale, Sickness Impact Profile) and disease stage, psychological, neuropsychological and neurological measures, and a significant correlation was also fount with each domain. The internal consistency reliability (alpha = 0.96), split half reliability (r12 = 0.97), and test-retest reliability (coefficients were 0.78 for 6 months and 0.67 for one year intervals between test and retest) were all found to high and adequately stable. Overall, these results indicate acceptable reliability and initial construct valididty for the NeuroQOL.
268.
Rizzo, Albert; Graap, Ken; McLay, Robert N.; Perlman, Karen; Rothbaum, Barbara O.; Reger, Greg; Parsons, Thomas D.; Difede, JoAnn; Pair, Jarrell
Virtual Iraq: Initial Case Reports from a VR Exposure Therapy Application for Combat-Related Post Traumatic Stress Disorder Journal Article
In: Virtual Rehabilitation, vol. 27, pp. 124–130, 2007.
@article{rizzo_virtual_2007,
title = {Virtual Iraq: Initial Case Reports from a VR Exposure Therapy Application for Combat-Related Post Traumatic Stress Disorder},
author = {Albert Rizzo and Ken Graap and Robert N. McLay and Karen Perlman and Barbara O. Rothbaum and Greg Reger and Thomas D. Parsons and JoAnn Difede and Jarrell Pair},
url = {http://ict.usc.edu/pubs/Virtual%20Iraq-%20Initial%20Case%20Reports%20from%20a%20VR%20Exposure%20Therapy%20Application%20for%20Combat-Related%20Post%20Traumatic%20Stress%20Disorder.pdf},
year = {2007},
date = {2007-01-01},
journal = {Virtual Rehabilitation},
volume = {27},
pages = {124–130},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale and brief description of a Virtual Iraq PTSD VR therapy application and present initial findings from two successfully treated patients. The VR treatment environment was created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far, Virtual Iraq consists of a series of customizable virtual scenarios designed to represent relevant Middle Eastern VR contexts for exposure therapy, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system deployed in Iraq and tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center and the results from two successfully treated patients are presented along with a delineation of our future plans for research and clinical care using this application.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale and brief description of a Virtual Iraq PTSD VR therapy application and present initial findings from two successfully treated patients. The VR treatment environment was created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far, Virtual Iraq consists of a series of customizable virtual scenarios designed to represent relevant Middle Eastern VR contexts for exposure therapy, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system deployed in Iraq and tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center and the results from two successfully treated patients are presented along with a delineation of our future plans for research and clinical care using this application.
269.
Parsons, Thomas D.; Rizzo, Albert; Bamattre, Jacob; Brennan, John
Virtual Reality Cognitive Performance Assessment Test Journal Article
In: Annual Review of CyberTherapy and Telemedicine, 2007.
@article{parsons_virtual_2007,
title = {Virtual Reality Cognitive Performance Assessment Test},
author = {Thomas D. Parsons and Albert Rizzo and Jacob Bamattre and John Brennan},
url = {http://ict.usc.edu/pubs/Virtual%20Reality%20Cognitive%20Performance%20Assessment%20Test.pdf},
year = {2007},
date = {2007-01-01},
journal = {Annual Review of CyberTherapy and Telemedicine},
abstract = {Virtual Reality Cognitive Performance Assessment Test (VRCPAT) is a virtual environment based measure of learning and memory. We examined convergent and discriminant validity and hypothesized that the VRCPAT’s Total Learning and Memory scores would correlate with other neuropsychological measures involving learning and memory, but not with measures involving potential confounds (i.e., Executive Functions; Attention; and Processing Speed). Using a sequential hierarchical strategy, each stage of test development did not proceed until specified criteria were met. The 15 minute VRCPAT battery and a 1.5 hour in-person neuropsychological assessment were conducted with a randomly selected sample of 20 healthy adults that included equivalent distributions of men and women from ethnically diverse populations. Results supported both convergent and discriminant validity. That is, findings suggest that the VRCPAT measures a capacity that is 1) consistent with that assessed by traditional paper and pencil measures involving learning and memory; and 2) inconsistent with that assessed by traditional paper and pencil measures assessing neurocognitive domains traditionally assumed to be other than learning and memory. We conclude that the VRCPAT is a valid test that provides a unique opportunity to reliably and efficiently study memory function within an ecologically valid environment.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Virtual Reality Cognitive Performance Assessment Test (VRCPAT) is a virtual environment based measure of learning and memory. We examined convergent and discriminant validity and hypothesized that the VRCPAT’s Total Learning and Memory scores would correlate with other neuropsychological measures involving learning and memory, but not with measures involving potential confounds (i.e., Executive Functions; Attention; and Processing Speed). Using a sequential hierarchical strategy, each stage of test development did not proceed until specified criteria were met. The 15 minute VRCPAT battery and a 1.5 hour in-person neuropsychological assessment were conducted with a randomly selected sample of 20 healthy adults that included equivalent distributions of men and women from ethnically diverse populations. Results supported both convergent and discriminant validity. That is, findings suggest that the VRCPAT measures a capacity that is 1) consistent with that assessed by traditional paper and pencil measures involving learning and memory; and 2) inconsistent with that assessed by traditional paper and pencil measures assessing neurocognitive domains traditionally assumed to be other than learning and memory. We conclude that the VRCPAT is a valid test that provides a unique opportunity to reliably and efficiently study memory function within an ecologically valid environment.
270.
Parsons, Thomas D.; Rogers, Steven A.; Hall, Colin D.; Robertson, R. Kevin
Motor Based Assessment of Neurocognitive Functioning in Resource-Limited International Settings. Journal Article
In: Journal of Clinical and Experimental Neuropsychology, vol. 29, pp. 59–66, 2007.
@article{parsons_motor_2007,
title = {Motor Based Assessment of Neurocognitive Functioning in Resource-Limited International Settings.},
author = {Thomas D. Parsons and Steven A. Rogers and Colin D. Hall and R. Kevin Robertson},
url = {http://ict.usc.edu/pubs/Motor%20based%20assessment%20of%20neurocognitive%20functioning%20in%20resource-limited%20Iinternational%20settings.pdf},
year = {2007},
date = {2007-01-01},
journal = {Journal of Clinical and Experimental Neuropsychology},
volume = {29},
pages = {59–66},
abstract = {This study compared variance accounted for by neuropsychological tests in both a brief motor battery and in a comprehensive neuropsychological battery. 327 HIV + subjects received a comprehensive cognitive battery and a shorter battery (Timed Gait, Grooved Pegboard, and Fingertapping). A significant correlation existed between the motor component tests and the more comprehensive battery (52% of variance). Adding Digit symbol and Trailmaking increased the amount of variance accounted for (73%). Motor battery sensitivity to impairment diagnosis was 0.79 and specificity was 0.76. A motor battery may have broader utility to diagnose and monitor HIV related neurocognitive disorders in international settings.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
This study compared variance accounted for by neuropsychological tests in both a brief motor battery and in a comprehensive neuropsychological battery. 327 HIV + subjects received a comprehensive cognitive battery and a shorter battery (Timed Gait, Grooved Pegboard, and Fingertapping). A significant correlation existed between the motor component tests and the more comprehensive battery (52% of variance). Adding Digit symbol and Trailmaking increased the amount of variance accounted for (73%). Motor battery sensitivity to impairment diagnosis was 0.79 and specificity was 0.76. A motor battery may have broader utility to diagnose and monitor HIV related neurocognitive disorders in international settings.
271.
Iudicello, Jennifer E.; Woods, Steven Paul; Parsons, Thomas D.; Moran, Lisa M.; Carey, Catherine L.; Grant, Igor
Verbal fluency in HIV infection: A meta-analytic review Journal Article
In: Journal of the International Neuropsychological Society, vol. 13, pp. 183–189, 2007.
@article{iudicello_verbal_2007,
title = {Verbal fluency in HIV infection: A meta-analytic review},
author = {Jennifer E. Iudicello and Steven Paul Woods and Thomas D. Parsons and Lisa M. Moran and Catherine L. Carey and Igor Grant},
url = {http://ict.usc.edu/pubs/Verbal%20fluency%20in%20HIV%20infection-%20A%20meta-analytic%20review.pdf},
doi = {10.10170S1355617707070221},
year = {2007},
date = {2007-01-01},
journal = {Journal of the International Neuropsychological Society},
volume = {13},
pages = {183–189},
abstract = {Given the largely prefrontostriatal neuropathogenesis of HIV-associated neurobehavioral deficits, it is often presumed that HIV infection leads to greater impairment on letter versus category fluency. A meta-analysis of the HIV verbal fluency literature was conducted (k 5 37, n 5 7110) to assess this hypothesis and revealed generally small effect sizes for both letter and category fluency, which increased in magnitude with advancing HIV disease severity. Across all studies, the mean effect size of category fluency was slightly larger than that of letter fluency. However, the discrepancy between category and letter fluency dissipated in a more conservative analysis of only those studies that included both tests. Thus, HIV-associated impairments in letter and category fluency are of similar magnitude, suggesting that mild word generation deficits are evident in HIV, regardless of whether traditional letter or semantic cues are used to guide the word search and retrieval process.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Given the largely prefrontostriatal neuropathogenesis of HIV-associated neurobehavioral deficits, it is often presumed that HIV infection leads to greater impairment on letter versus category fluency. A meta-analysis of the HIV verbal fluency literature was conducted (k 5 37, n 5 7110) to assess this hypothesis and revealed generally small effect sizes for both letter and category fluency, which increased in magnitude with advancing HIV disease severity. Across all studies, the mean effect size of category fluency was slightly larger than that of letter fluency. However, the discrepancy between category and letter fluency dissipated in a more conservative analysis of only those studies that included both tests. Thus, HIV-associated impairments in letter and category fluency are of similar magnitude, suggesting that mild word generation deficits are evident in HIV, regardless of whether traditional letter or semantic cues are used to guide the word search and retrieval process.
272.
Macedonio, Mary F.; Parsons, Thomas D.; Digiuseppe, Raymond A.; Wiederhold, Brenda K.; Rizzo, Albert
Immersiveness and Physiological Arousal within Panoramic Video-Based Virtual Reality Journal Article
In: CyberPsychology and Behavior, vol. 10, no. 4, pp. 508–515, 2007.
@article{macedonio_immersiveness_2007,
title = {Immersiveness and Physiological Arousal within Panoramic Video-Based Virtual Reality},
author = {Mary F. Macedonio and Thomas D. Parsons and Raymond A. Digiuseppe and Brenda K. Wiederhold and Albert Rizzo},
url = {http://ict.usc.edu/pubs/Immersiveness%20and%20Physiological%20Arousal%20within%20Panoramic%20Video-Based%20Virtual%20Reality.pdf},
year = {2007},
date = {2007-01-01},
journal = {CyberPsychology and Behavior},
volume = {10},
number = {4},
pages = {508–515},
abstract = {In this paper, we discuss findings from a study that used panoramic video-based virtual environments (PVVEs) to induce self-reported anger. The study assessed "immersiveness" and physiological correlates of anger arousal (i.e., heart rate, blood pressure, galvanic skin response [GSR], respiration, and skin temperature). Results indicate that over time, panoramic video-based virtual scenarios can be, at the very least, physiologically arousing. Further, it can be affirmed from the results that hypnotizability, as defined by the applied measures, interacts with group on physiological arousal measures. Hence, physiological arousal appeared to be moderated by participant hypnotizability and absorption levels.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
In this paper, we discuss findings from a study that used panoramic video-based virtual environments (PVVEs) to induce self-reported anger. The study assessed "immersiveness" and physiological correlates of anger arousal (i.e., heart rate, blood pressure, galvanic skin response [GSR], respiration, and skin temperature). Results indicate that over time, panoramic video-based virtual scenarios can be, at the very least, physiologically arousing. Further, it can be affirmed from the results that hypnotizability, as defined by the applied measures, interacts with group on physiological arousal measures. Hence, physiological arousal appeared to be moderated by participant hypnotizability and absorption levels.
273.
Buckwalter, John Galen; Geiger, A. M.; Parsons, Thomas D.; Handler, J.; Howes, J.; Lehmer, R. R.
Cognitive Effects of Short-term Use of Raloxifene: A Randomized Clinical Trial Journal Article
In: International Journal of Neuroscience, vol. 117, pp. 1579–1590, 2007.
@article{buckwalter_cognitive_2007,
title = {Cognitive Effects of Short-term Use of Raloxifene: A Randomized Clinical Trial},
author = {John Galen Buckwalter and A. M. Geiger and Thomas D. Parsons and J. Handler and J. Howes and R. R. Lehmer},
url = {http://ict.usc.edu/pubs/Cognitive%20Effects%20of%20Short-term%20Use%20of%20Raloxifene-%20A%20Randomized%20Clinical%20Trial.pdf},
year = {2007},
date = {2007-01-01},
journal = {International Journal of Neuroscience},
volume = {117},
pages = {1579–1590},
abstract = {Two questions regarding findings from the Women's Health Initiative are (1) What is the effect of various hormonal regimens including selective estrogen receptor modulators? and (2) Is the negative effect on cognitive functioning related to the older age (65+years) if the women? This study addresses these two questions in a short-term randomized trial of the effects of raloxifene versus alendronate on cognition. The study found only one significant interaction where the raloxifene and alendronate group changed differently across the two testing occasions. Hence, raloxifene does not have any impact, positive or negative, on short-term cognitive functioning when compared to alendronate.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Two questions regarding findings from the Women's Health Initiative are (1) What is the effect of various hormonal regimens including selective estrogen receptor modulators? and (2) Is the negative effect on cognitive functioning related to the older age (65+years) if the women? This study addresses these two questions in a short-term randomized trial of the effects of raloxifene versus alendronate on cognition. The study found only one significant interaction where the raloxifene and alendronate group changed differently across the two testing occasions. Hence, raloxifene does not have any impact, positive or negative, on short-term cognitive functioning when compared to alendronate.
274.
Robertson, R. Kevin; Smurzynski, Marlene; Parsons, Thomas D.; Wu, Kunling; Bosch, Ronald J.; Wu, Julia; McArthur, Justin C.; Collier, Ann C.; Evans, Scott R.; Ellis, Ron J.
The Prevalence and Incidence of Neurocognitive Impairment in the HAART Era Journal Article
In: AIDS, vol. 21, pp. 1915–1921, 2007, ISSN: 0269-9370.
@article{robertson_prevalence_2007,
title = {The Prevalence and Incidence of Neurocognitive Impairment in the HAART Era},
author = {R. Kevin Robertson and Marlene Smurzynski and Thomas D. Parsons and Kunling Wu and Ronald J. Bosch and Julia Wu and Justin C. McArthur and Ann C. Collier and Scott R. Evans and Ron J. Ellis},
url = {http://ict.usc.edu/pubs/The%20prevalence%20and%20incidence%20of%20neurocognitive%20impairment%20in%20the%20HAART%20era.pdf},
issn = {0269-9370},
year = {2007},
date = {2007-01-01},
journal = {AIDS},
volume = {21},
pages = {1915–1921},
abstract = {Objectives: HAART suppresses HIV viral replication and restores immune function. The effects of HAART on neurological disease are less well understood. The aim of this study was to assess the prevalence and incidence of neurocognitive impairment in individuals who initiated HAART as part of an AIDS clinical trial. Design: A prospective cohort study of HIV-positive patients enrolled in randomized antiretroviral trials, the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) study. Methods: We examined the association between baseline and demographic characteristics and neurocognitive impairment among 1160 subjects enrolled in the ALLRT study. Results: A history of immunosuppression (nadir CD4 cell count textbackslashtextbackslashtextbackslashtextbackslashtextless 200 cells/ml) was associated with an increase in prevalent neurocognitive impairment. There were no signiï¬cant virological and immunological predictors of incident neurocognitive impairment. Current immune status (low CD4 cell count) was associated with sustained prevalent impairment. Conclusion: The association of previous advanced immunosuppression with prevalent and sustained impairment suggests that there is a non-reversible component of neural injury that tracks with a history of disease progression. The association of sustained impairment with worse current immune status (low CD4 cell count) suggests that restoring immunocompetence increases the likelihood of neurocognitive recovery. Finally, the lack of association between incident neurocognitive impairment and virological and immunological indicators implies that neural injury continues in some patients regardless of the success of antiretroviral therapy on these laboratory measures.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Objectives: HAART suppresses HIV viral replication and restores immune function. The effects of HAART on neurological disease are less well understood. The aim of this study was to assess the prevalence and incidence of neurocognitive impairment in individuals who initiated HAART as part of an AIDS clinical trial. Design: A prospective cohort study of HIV-positive patients enrolled in randomized antiretroviral trials, the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) study. Methods: We examined the association between baseline and demographic characteristics and neurocognitive impairment among 1160 subjects enrolled in the ALLRT study. Results: A history of immunosuppression (nadir CD4 cell count textbackslashtextbackslashtextbackslashtextbackslashtextless 200 cells/ml) was associated with an increase in prevalent neurocognitive impairment. There were no signiï¬cant virological and immunological predictors of incident neurocognitive impairment. Current immune status (low CD4 cell count) was associated with sustained prevalent impairment. Conclusion: The association of previous advanced immunosuppression with prevalent and sustained impairment suggests that there is a non-reversible component of neural injury that tracks with a history of disease progression. The association of sustained impairment with worse current immune status (low CD4 cell count) suggests that restoring immunocompetence increases the likelihood of neurocognitive recovery. Finally, the lack of association between incident neurocognitive impairment and virological and immunological indicators implies that neural injury continues in some patients regardless of the success of antiretroviral therapy on these laboratory measures.
275.
Rizzo, Albert; Pair, Jarrell; Parsons, Thomas D.; Liewer, Matt; Graap, Ken; Difede, JoAnn; Rothbaum, Barbara O.; Reger, Greg; Roy, Michael
A Virtual Reality Therapy Application for OEF/OIF Combat-related Post Traumatic Stress Disorder Proceedings Article
In: Proceedings of the 25th Army Science Conference, Orlando, FL, 2006.
@inproceedings{rizzo_virtual_2006-1,
title = {A Virtual Reality Therapy Application for OEF/OIF Combat-related Post Traumatic Stress Disorder},
author = {Albert Rizzo and Jarrell Pair and Thomas D. Parsons and Matt Liewer and Ken Graap and JoAnn Difede and Barbara O. Rothbaum and Greg Reger and Michael Roy},
url = {http://ict.usc.edu/pubs/A%20VIRTUAL%20REALITY%20THERAPY%20APPLICATION%20FOR%20OEF%20OIF%20COMBAT-RELATED%20POST%20TRAUMATIC%20STRESS%20DISORDER.pdf},
year = {2006},
date = {2006-11-01},
booktitle = {Proceedings of the 25th Army Science Conference},
address = {Orlando, FL},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system in Iraq tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center. Other sites are preparing to use the application for a variety of PTSD and VR research purposes.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experience including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that at least 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) delivered exposure therapy for PTSD has been used with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-centered design feedback needed to iteratively evolve the system was gathered from returning Iraq War veterans in the USA and from a system in Iraq tested by an Army Combat Stress Control Team. Clinical trials are currently underway at Camp Pendleton and at the San Diego Naval Medical Center. Other sites are preparing to use the application for a variety of PTSD and VR research purposes.
276.
Marsella, Stacy C.; Carnicke, Sharon Marie; Gratch, Jonathan; Okhmatovskaia, Anna; Rizzo, Albert
An Exploration of Delsartes Structural Acting System Proceedings Article
In: Proceedings of the 6th International Conference on Intelligent Virtual Agents (IVA), pp. 80–92, Marina del Rey, CA, 2006.
@inproceedings{marsella_exploration_2006,
title = {An Exploration of Delsartes Structural Acting System},
author = {Stacy C. Marsella and Sharon Marie Carnicke and Jonathan Gratch and Anna Okhmatovskaia and Albert Rizzo},
url = {http://ict.usc.edu/pubs/An%20Exploration%20of%20Delsarte%E2%80%99s%20Structural%20Acting%20System.pdf},
year = {2006},
date = {2006-08-01},
booktitle = {Proceedings of the 6th International Conference on Intelligent Virtual Agents (IVA)},
pages = {80–92},
address = {Marina del Rey, CA},
abstract = {The designers of virtual agents often draw on a large research literature in psychology, linguistics and human ethology to design embodied agents that can interact with people. In this paper, we consider a structural acting system developed by Francois Delsarte as a possible resource in designing the nonverbal behavior of embodied agents. Using human subjects,we evaluate one component of the system, Delsarte's Cube, that addresses the meaning of differing attitudes of the hand in gestures.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
The designers of virtual agents often draw on a large research literature in psychology, linguistics and human ethology to design embodied agents that can interact with people. In this paper, we consider a structural acting system developed by Francois Delsarte as a possible resource in designing the nonverbal behavior of embodied agents. Using human subjects,we evaluate one component of the system, Delsarte's Cube, that addresses the meaning of differing attitudes of the hand in gestures.
277.
Parsons, Thomas D.; Rogers, Steven A.; Braaten, Alyssa J.; Woods, Steven Paul; Tröster, Alexander I.
Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis Journal Article
In: Lancet Neurology, vol. 5, pp. 578–588, 2006.
@article{parsons_cognitive_2006,
title = {Cognitive sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a meta-analysis},
author = {Thomas D. Parsons and Steven A. Rogers and Alyssa J. Braaten and Steven Paul Woods and Alexander I. Tröster},
url = {http://ict.usc.edu/pubs/Cognitive%20sequelae%20of%20subthalamic%20nucleus%20deep%20brain%20stimulation%20in%20Parkinson%E2%80%99s%20disease-%20a%20meta-analysis.pdf},
year = {2006},
date = {2006-06-01},
journal = {Lancet Neurology},
volume = {5},
pages = {578–588},
abstract = {Summary: Background Deep brain stimulation of the subthalamic nucleus (STN DBS) is an increasingly common treatment for Parkinson's disease. Qualitative reviews have concluded that diminished verbal fluency is common after STN DBS, but that changes in global cognitive abilities, attention, executive functions, and memory are only inconsistently observed and, when present, often nominal or transient. We did a quantitative meta-analysis to improve understanding of the variability and clinical signiï¬cance of cognitive dysfunction after STN DBS. Methods: We searched MedLine, PsycLIT, and ISI Web of Science electronic databases for articles published between 1990 and 2006, and extracted information about number of patients, exclusion criteria, conï¬rmation of target by microelectrode recording, veriï¬cation of electrode placement via radiographic means, stimulation parameters, assessment time points, assessment measures, whether patients were on levodopa or dopaminomimetics, and summary statistics needed for computation of effect sizes. We used the random-effects meta-analytical model to assess continuous outcomes before and after STN DBS. Findings: Of 40 neuropsychological studies identiï¬ed, 28 cohort studies (including 612 patients) were eligible for inclusion in the meta-analysis. After adjusting for heterogeneity of variance in study effect sizes, the random effects meta-analysis revealed signiï¬cant, albeit small, declines in executive functions and verbal learning and memory. Moderate declines were only reported in semantic (Cohen's d 0·73) and phonemic verbal fluency (0·51). Changes in verbal fluency were not related to patient age, disease duration, stimulation parameters, or change in dopaminomimetic dose after surgery. Interpretation: STN DBS, in selected patients, seems relatively safe from a cognitive standpoint. However, diffculty in identiï¬cation of factors underlying changes in verbal fluency draws attention to the need for uniform and detailed reporting of patient selection, demographic, disease, treatment, surgical, stimulation, and clinical outcome parameters.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Summary: Background Deep brain stimulation of the subthalamic nucleus (STN DBS) is an increasingly common treatment for Parkinson's disease. Qualitative reviews have concluded that diminished verbal fluency is common after STN DBS, but that changes in global cognitive abilities, attention, executive functions, and memory are only inconsistently observed and, when present, often nominal or transient. We did a quantitative meta-analysis to improve understanding of the variability and clinical signiï¬cance of cognitive dysfunction after STN DBS. Methods: We searched MedLine, PsycLIT, and ISI Web of Science electronic databases for articles published between 1990 and 2006, and extracted information about number of patients, exclusion criteria, conï¬rmation of target by microelectrode recording, veriï¬cation of electrode placement via radiographic means, stimulation parameters, assessment time points, assessment measures, whether patients were on levodopa or dopaminomimetics, and summary statistics needed for computation of effect sizes. We used the random-effects meta-analytical model to assess continuous outcomes before and after STN DBS. Findings: Of 40 neuropsychological studies identiï¬ed, 28 cohort studies (including 612 patients) were eligible for inclusion in the meta-analysis. After adjusting for heterogeneity of variance in study effect sizes, the random effects meta-analysis revealed signiï¬cant, albeit small, declines in executive functions and verbal learning and memory. Moderate declines were only reported in semantic (Cohen's d 0·73) and phonemic verbal fluency (0·51). Changes in verbal fluency were not related to patient age, disease duration, stimulation parameters, or change in dopaminomimetic dose after surgery. Interpretation: STN DBS, in selected patients, seems relatively safe from a cognitive standpoint. However, diffculty in identiï¬cation of factors underlying changes in verbal fluency draws attention to the need for uniform and detailed reporting of patient selection, demographic, disease, treatment, surgical, stimulation, and clinical outcome parameters.
278.
Parsons, Thomas D.; Tucker, Karen A.; Hall, Colin D.; Robertson, Wendy T.; Eron, Joseph J.; Fried, Michael W.; Robertson, R. Kevin
Neurocognitive functioning and HAART in HIV and hepatitis C virus co-infection Journal Article
In: AIDS, vol. 20, pp. 1591–1595, 2006.
@article{parsons_neurocognitive_2006,
title = {Neurocognitive functioning and HAART in HIV and hepatitis C virus co-infection},
author = {Thomas D. Parsons and Karen A. Tucker and Colin D. Hall and Wendy T. Robertson and Joseph J. Eron and Michael W. Fried and R. Kevin Robertson},
url = {http://ict.usc.edu/pubs/Neurocognitive%20functioning%20and%20HAART%20in%20HIV%20and%20hepatitis%20C%20virus%20co-infection.pdf},
year = {2006},
date = {2006-05-01},
journal = {AIDS},
volume = {20},
pages = {1591–1595},
abstract = {Objectives: This study examined the effects of HAART on neurocognitive functioning in persons with hepatitis C virus (HCV) and HIV co-infection. Design: A prospective study examining neurocognitive performance before and after HAART initiation. Method: Participant groups included a mono-infected group (45 HIV/HCV-participants) and a co-infected group (20 HIV/HCV participants). A neuropsychological battery (attention/concentration, psychomotor speed, executive functioning, verbal memory, visual memory, ï¬ne motor, and gross motor functioning) was used to evaluate all participants. After 6 months of HAART, 31 HIV mono-infected and 13 HCV/ HIV co-infected participants were reevaluated. Results: Neurocognitive functioning by domain revealed signiï¬cantly worse performance in the co-infected group when compared to the monoinfected group on domains of visual memory and ï¬ne motor functioning. Assessment of neurocognitive functioning after antiretroviral therapy revealed that the co-infected group was no longer performing worse than the monoinfected group. Conclusions: The ï¬ndings of the current study suggest that persons with HCV/HIV co-infection may have greater neurocognitive declines than persons with HIV infection alone. HCV/HIV co-infection may accelerate the progression of HIV related neurocognitive decline.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Objectives: This study examined the effects of HAART on neurocognitive functioning in persons with hepatitis C virus (HCV) and HIV co-infection. Design: A prospective study examining neurocognitive performance before and after HAART initiation. Method: Participant groups included a mono-infected group (45 HIV/HCV-participants) and a co-infected group (20 HIV/HCV participants). A neuropsychological battery (attention/concentration, psychomotor speed, executive functioning, verbal memory, visual memory, ï¬ne motor, and gross motor functioning) was used to evaluate all participants. After 6 months of HAART, 31 HIV mono-infected and 13 HCV/ HIV co-infected participants were reevaluated. Results: Neurocognitive functioning by domain revealed signiï¬cantly worse performance in the co-infected group when compared to the monoinfected group on domains of visual memory and ï¬ne motor functioning. Assessment of neurocognitive functioning after antiretroviral therapy revealed that the co-infected group was no longer performing worse than the monoinfected group. Conclusions: The ï¬ndings of the current study suggest that persons with HCV/HIV co-infection may have greater neurocognitive declines than persons with HIV infection alone. HCV/HIV co-infection may accelerate the progression of HIV related neurocognitive decline.
279.
Rizzo, Albert; Pair, Jarrell; Graap, Ken; Manson, Brian; McNerney, Peter J.; Wiederhold, Brenda K.; Wiederhold, Mark; Spira, James
A Virtual Reality Exposure Therapy Application for Iraq War Military Personnel with Post Traumatic Stress Disorder: From Training to Toy to Treatment Proceedings Article
In: NATO Advanced Research Workshop on Novel Approached to the Diagnosis and Treatment of Posttraumatic Stress Disorder, 2006.
@inproceedings{rizzo_virtual_2006,
title = {A Virtual Reality Exposure Therapy Application for Iraq War Military Personnel with Post Traumatic Stress Disorder: From Training to Toy to Treatment},
author = {Albert Rizzo and Jarrell Pair and Ken Graap and Brian Manson and Peter J. McNerney and Brenda K. Wiederhold and Mark Wiederhold and James Spira},
url = {http://ict.usc.edu/pubs/A%20Virtual%20Reality%20Exposure%20Therapy%20Application%20for%20Iraq%20War%20Military%20Personnel%20with%20Post%20Traumatic%20Stress%20Disorder-%20From%20Training%20to%20Toy%20to%20Treatment.pdf},
year = {2006},
date = {2006-03-01},
booktitle = {NATO Advanced Research Workshop on Novel Approached to the Diagnosis and Treatment of Posttraumatic Stress Disorder},
abstract = {Post Traumatic Stress Disorder is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to specify the rationale, design and development of a Virtual Iraq PTSD VR application that has been created from the virtual assets that were initially developed for a combat tactical training simulation, which then served as the inspiration for the X-Box game entitled Full Spectrum Warrior.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to specify the rationale, design and development of a Virtual Iraq PTSD VR application that has been created from the virtual assets that were initially developed for a combat tactical training simulation, which then served as the inspiration for the X-Box game entitled Full Spectrum Warrior.
280.
Pair, Jarrell; Allen, Brian; Dautricourt, Matthieu; Treskunov, Anton; Liewer, Matt; Graap, Ken; Reger, Greg; Rizzo, Albert
A Virtual Reality Exposure Therapy Application for Iraq War Post Traumatic Stress Disorder Proceedings Article
In: Proceedings of the IEEE VR 2006 Conference, pp. 64–71, Alexandria, VA, 2006.
@inproceedings{pair_virtual_2006,
title = {A Virtual Reality Exposure Therapy Application for Iraq War Post Traumatic Stress Disorder},
author = {Jarrell Pair and Brian Allen and Matthieu Dautricourt and Anton Treskunov and Matt Liewer and Ken Graap and Greg Reger and Albert Rizzo},
url = {http://ict.usc.edu/pubs/A%20Virtual%20Reality%20Exposure%20Therapy%20Application%20for%20Iraq%20War%20Post%20Traumatic%20Stress%20Disorder.pdf},
year = {2006},
date = {2006-03-01},
booktitle = {Proceedings of the IEEE VR 2006 Conference},
pages = {64–71},
address = {Alexandria, VA},
abstract = {Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-Centered tests with the application are currently underway at the Naval Medical Center–San Diego and within an Army Combat Stress Control Team in Iraq with clinical trials scheduled to commence in February 2006.},
keywords = {},
pubstate = {published},
tppubtype = {inproceedings}
}
Post Traumatic Stress Disorder (PTSD) is reported to be caused by traumatic events that are outside the range of usual human experiences including (but not limited to) military combat, violent personal assault, being kidnapped or taken hostage and terrorist attacks. Initial data suggests that 1 out of 6 Iraq War veterans are exhibiting symptoms of depression, anxiety and PTSD. Virtual Reality (VR) exposure treatment has been used in previous treatments of PTSD patients with reports of positive outcomes. The aim of the current paper is to present the rationale, technical specifications, application features and user-centered design process for the development of a Virtual Iraq PTSD VR therapy application. The VR treatment environment is being created via the recycling of virtual graphic assets that were initially built for the U.S. Army-funded combat tactical simulation scenario and commercially successful X-Box game, Full Spectrum Warrior, in addition to other available and newly created assets. Thus far we have created a series of customizable virtual scenarios designed to represent relevant contexts for exposure therapy to be conducted in VR, including a city and desert road convoy environment. User-Centered tests with the application are currently underway at the Naval Medical Center–San Diego and within an Army Combat Stress Control Team in Iraq with clinical trials scheduled to commence in February 2006.
Filter
Sorry, no publications matched your criteria.